[Term]
id: PR:000045317
name: histone H4, initiator methionine removed trimethylated 1 (human)
def: "A histone H4 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-21 of the amino acid sequence represented by UniProtKB:P62805. UniProtKB:P62805, 2-103, Lys-21, MOD:00083." [HIstome_var_Hs:Histone_H4, PMID:15145825, PMID:15765097, PMID:15765097, PMID:20018718, PMID:20495075, PMID:20843831, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H4:H4K20me3" BROAD [HIstome_ptm_Hs:H4K20me3]
synonym: "hH4/InitMet-/Me3:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000158320, Lys-21, MOD:00083" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P62805, 2-103, Lys-21, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5651656 "PR:000045317 located_in GO:0005654"
xref: TDR:13072
is_a: PR:P62805 ! histone H4 (human)
relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine