[Term]
id: PR:000000003
name: HLH DNA-binding protein inhibitor
def: "A protein that belongs to the clade D of the bHLH proteins (see PMID:20219281) with a core domain composition consisting of a helix-loop-helix DNA-binding domain (Pfam:PF00010) (HLH), common to the basic HLH family of transcription factors, but lacking the DNA binding domain to the consensus E box response element (CANNTG). By binding to basic HLH transcription factors, proteins in this class regulate gene expression." [PMID:20219281, PRO:CNA]
comment: Category=family.
synonym: "ID protein" RELATED []
synonym: "bHLH clade D" BROAD [PMID:20219281]
synonym: "bHLH class V" BROAD [PMID:8018712]
synonym: "DNA-binding protein inhibitor ID" EXACT []
xref: PIRSF:PIRSF005808
is_a: PR:000000001 ! protein