[Term]
id: PR:000000017
name: interferon gamma
def: "A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions." [PRO:CNA]
comment: Category=gene.
synonym: "IFNG" EXACT PRO-short-label [PRO:DNx]
synonym: "IFN-gamma" EXACT []
synonym: "immune interferon" EXACT []
xref: PIRSF:PIRSF001936
is_a: PR:000024990 ! type II interferon