[Term] id: PR:000000023 name: retinoblastoma-like protein def: "A protein that has a core domain composition consisting of a Retinoblastoma-associated protein A domain (Pfam:PF01858) followed by a Retinoblastoma-associated protein B domain (Pfam:PF01857). The retinoblastoma-like proteins are key regulators of entry into cell division. They are directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF037408 is_a: PR:000000001 ! protein