[Term]
id: PR:000025411
name: TGF-beta receptor type-1 proteolytic cleavage product
def: "A TGF-beta receptor type-1 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "TGFBR1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000000047 ! TGF-beta receptor type-1

[Term]
id: PR:000049432
name: TGF-beta receptor type-1, signal peptide removed form (human)
def: "A TGF-beta receptor type-1 (human) that has had the signal peptide removed. UniProtKB:P36897, 34-503." [PRO:DNx, Reactome:R-HSA-170839]
comment: Category=organism-modification.
synonym: "PRO_0000024423" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTGFBR1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897, 34-503" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-170839 "PR:000049432 located_in GO:0005886"
intersection_of: PR:P36897 ! TGF-beta receptor type-1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049433
name: TGF-beta receptor type-1, signal peptide removed ubiquitinated form (human)
def: "A TGF-beta receptor type-1 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:P36897, 34-503, MOD:01148." [PRO:DNx, Reactome:R-HSA-8869461]
comment: Category=organism-modification.
synonym: "hTGFBR1/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000024423, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P36897, 34-503, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8869461 "PR:000049433 located_in GO:0005886"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:P36897 ! TGF-beta receptor type-1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q64729-2
name: TGF-beta receptor type-1 isoform m2 (mouse)
def: "A TGF-beta receptor type-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64729-2." [PRO:DNx, UniProtKB:Q64729]
comment: Category=organism-sequence.
synonym: "mTGFBR1/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64729-2
is_a: PR:Q64729 ! TGF-beta receptor type-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000003173
name: TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated and ubiquitinated form
def: "A TGF-beta receptor type-1 isoform 1, signal peptide removed form that has been post-translationally modified to include phosphorylated and ubiquitinated residues." [PID:TGFB/TGFBR2/TGFBR1/WWP1/SMAD8, PRO:CNA]
comment: Category=modification.
synonym: "TGFBR1 inactive" BROAD [PRO:DNx]
synonym: "TGFBR1/iso:1/SigPep-/PhosUbiq+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:000000522 ! TGF-beta receptor type-1 isoform 1, signal peptide removed form

[Term]
id: PR:000000189
name: TGF-beta receptor type-1 sequence variant K232E (human)
def: "A TGF-beta receptor type-1 (human) that has a Glu residue at the position equivalent to Lys-232 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Lys-232, CHEBI:29972." [PMID:16928994, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:K232E" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Lys-232, CHEBI:29972" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 2 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_029481
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000188
name: TGF-beta receptor type-1 sequence variant 11 (human)
def: "A TGF-beta receptor type-1 (human) that has a three-residue deletion at the position equivalent to region 24-26 of the amino acid sequence represented by UniProtKB:P36897-1. UniProtKB:P36897, 1-23, 27-503." [PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: This deletion is within the signal peptide.
synonym: "hTGFBR1/var:11" EXACT PRO-short-label [PRO:DNx]
synonym: "TGFBR1*6A (human)" RELATED []
synonym: "UniProtKB:P36897, 1-23, 27-503" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P36897-1, 1-23, 27-503" NARROW PRO-proteoform-std [PRO:DAN]
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036432
name: TGF-beta receptor type-1 isoform 1, signal peptide removed form (human)
def: "A TGF-beta receptor type-1 isoform 1, signal peptide removed form in human. UniProtKB:P36897-1, 25-503." [PMID:8242743, PRO:CNA]
comment: Category=organism-modification.
synonym: "hTGFBR1/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, 25-503" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000522 ! TGF-beta receptor type-1 isoform 1, signal peptide removed form

[Term]
id: PR:000000047
name: TGF-beta receptor type-1
def: "A TGF-beta superfamily receptor type-1 that is a translation product of the human TGFBR1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "ALK5" RELATED Gene-based []
synonym: "ESK2" EXACT []
synonym: "SKR4" RELATED Gene-based []
synonym: "ALK-5" EXACT []
synonym: "TGFBR1" EXACT PRO-short-label [PRO:DNx]
synonym: "TGFR-1" BROAD []
synonym: "TbetaR-I" BROAD []
synonym: "TGF-beta receptor type I" BROAD []
synonym: "TGF-beta type I receptor" BROAD []
synonym: "activin receptor-like kinase 5" EXACT []
synonym: "serine/threonine-protein kinase receptor R4" EXACT []
synonym: "transforming growth factor-beta receptor type I" BROAD []
xref: IUPHARobj:1788
is_a: PR:000000006 ! TGF-beta superfamily receptor type-1

[Term]
id: PR:000036434
name: TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse)
def: "A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in mouse. UniProtKB:Q64729-1, 23-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PMID:12065756, PRO:CNA]
comment: Category=organism-modification.
synonym: "mTGFBR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q64729-1, 23-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000523 ! TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000000185
name: TGF-beta receptor type-1 isoform 1
def: "A TGF-beta receptor type-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36897-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "TGFBR1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000047 ! TGF-beta receptor type-1

[Term]
id: PR:000000187
name: TGF-beta receptor type-1 sequence variant 10 (human)
def: "A TGF-beta receptor type-1 (human) that has an insertion of an Ala residue at the position equivalent to Ala-26 of the amino acid sequence represented by UniProtKB:P36897." [PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "TGFBR1*10A" RELATED []
synonym: "hTGFBR1/var:10" EXACT PRO-short-label [PRO:DNx]
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000186
name: TGF-beta receptor type-1 sequence variant T200I (human)
def: "A TGF-beta receptor type-1 (human) that has an Ile residue at the position equivalent to Thr-200 of the amino acid sequence represented by UniProtKB:P36897. UniProtKB:P36897, Thr-200, CHEBI:30009." [PMID:15731757, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:T200I" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897, Thr-200, CHEBI:30009" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "UniProtKB:P36897-1, Thr-200, CHEBI:30009" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 1 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_022344
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000408
name: TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form
def: "A TGF-beta receptor type-1 isoform 1, signal peptide removed form that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "TGFBR1/iso:1/SigPep-/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000000522 ! TGF-beta receptor type-1 isoform 1, signal peptide removed form

[Term]
id: PR:P80204
name: TGF-beta receptor type-1 (rat)
def: "A TGF-beta receptor type-1 that is encoded in the genome of rat." [OMA:P80204, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tgfbr1" RELATED Gene-based [UniProtKB:P80204]
synonym: "rTGFBR1" EXACT PRO-short-label [PRO:DNx]
synonym: "SKR4 (rat)" EXACT [UniProtKB:P80204]
synonym: "TGFR-1 (rat)" EXACT [UniProtKB:P80204]
synonym: "TbetaR-I (rat)" EXACT [UniProtKB:P80204]
synonym: "TGF-beta receptor type I (rat)" EXACT [UniProtKB:P80204]
synonym: "TGF-beta type I receptor (rat)" EXACT [UniProtKB:P80204]
synonym: "serine/threonine-protein kinase receptor R4 (rat)" EXACT [UniProtKB:P80204]
synonym: "transforming growth factor-beta receptor type I (rat)" EXACT [UniProtKB:P80204]
xref: UniProtKB:P80204
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000047 ! TGF-beta receptor type-1
relationship: has_gene_template RGD:3852 ! Tgfbr1 (rat)

[Term]
id: PR:000000523
name: TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
def: "A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form in which the phosphorylation occurs within the GS-motif by TGFBR2. Phosphorylation of any of the Ser or Thr seems to be sufficient to transduce signal, however full activation is achieved when five of these residues are phosphorylated. Example: UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PMID:7774578, PMID:8947046]
comment: Category=modification.
synonym: "TGFBR1 active" EXACT []
synonym: "TGFBR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000408 ! TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000000522
name: TGF-beta receptor type-1 isoform 1, signal peptide removed form
def: "A TGF-beta receptor type-1 isoform 1 that has had the signal peptide removed to yield the mature protein." [PRO:CNA]
comment: Category=modification.
synonym: "TGFBR1 inactive" BROAD [PRO:DNx]
synonym: "TGFBR1/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "TGF-beta receptor type-1 isoform 1 cleaved 1" EXACT []
intersection_of: PR:000000185 ! TGF-beta receptor type-1 isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P36897-1
name: TGF-beta receptor type-1 isoform 1 (human)
def: "A TGF-beta receptor type-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hTGFBR1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36897-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000185 ! TGF-beta receptor type-1 isoform 1

[Term]
id: PR:P36897-3
name: TGF-beta receptor type-1 isoform h3 (human)
def: "A TGF-beta receptor type-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36897-3." [PRO:DNx, UniProtKB:P36897]
comment: Category=organism-sequence.
synonym: "hTGFBR1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36897-3
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P36897-2
name: TGF-beta receptor type-1 isoform h2 (human)
def: "A TGF-beta receptor type-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36897-2." [PRO:DNx, UniProtKB:P36897]
comment: Category=organism-sequence.
synonym: "hTGFBR1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "TGF-beta receptor type-1 isoform B (human)" EXACT [UniProtKB:P36897]
xref: UniProtKB:P36897-2
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000025932
name: TGF-beta receptor type-1, signal peptide removed form
def: "A TGF-beta receptor type-1 that has had the signal peptide removed." [PRO:CNA]
comment: Category=modification.
synonym: "TGFBR1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000047 ! TGF-beta receptor type-1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000025959
name: TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
def: "A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human. Phosphorylation occurs by the action of active TGF-beta receptor type-2 within the GS-motifs. UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PMID:7774578, PMID:8947046]
comment: Category=organism-modification. Kinase=("TGFBR2"; PR:000025962; Ser-165/Thr-185/Thr-186/Ser-187/Ser-189/Ser-191).
synonym: "hTGFBR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-170849 "PR:000025959 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000523 ! TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:P36897
name: TGF-beta receptor type-1 (human)
def: "A TGF-beta receptor type-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P36897]
comment: Category=organism-gene.
synonym: "ALK5" RELATED Gene-based [UniProtKB:P36897]
synonym: "SKR4" RELATED Gene-based [UniProtKB:P36897]
synonym: "TGFBR1" RELATED Gene-based [UniProtKB:P36897]
synonym: "hTGFBR1" EXACT PRO-short-label [PRO:DNx]
synonym: "ALK-5 (human)" EXACT [UniProtKB:P36897]
synonym: "TGFR-1 (human)" EXACT [UniProtKB:P36897]
synonym: "TbetaR-I (human)" EXACT [UniProtKB:P36897]
synonym: "TGF-beta receptor type I (human)" EXACT [UniProtKB:P36897]
synonym: "TGF-beta type I receptor (human)" EXACT [UniProtKB:P36897]
synonym: "activin receptor-like kinase 5 (human)" EXACT [UniProtKB:P36897]
synonym: "serine/threonine-protein kinase receptor R4 (human)" EXACT [UniProtKB:P36897]
synonym: "transforming growth factor-beta receptor type I (human)" EXACT [UniProtKB:P36897]
synonym: "activin A receptor type II-like protein kinase of 53kD (human)" EXACT [UniProtKB:P36897]
xref: DTO:03100523
xref: UniProtKB:P36897
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000047 ! TGF-beta receptor type-1
relationship: has_gene_template HGNC:11772 ! TGFBR1 (human)

[Term]
id: PR:Q64729-1
name: TGF-beta receptor type-1 isoform 1 (mouse)
def: "A TGF-beta receptor type-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mTGFBR1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64729-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000185 ! TGF-beta receptor type-1 isoform 1

[Term]
id: PR:000000196
name: TGF-beta receptor type-1 sequence variant R487W (human)
def: "A TGF-beta receptor type-1 (human) that has a Trp residue at the position equivalent to Arg-487 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Arg-487, CHEBI:29954." [PMID:16928994, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:R487W" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Arg-487, CHEBI:29954" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 9 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_029485
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q64729
name: TGF-beta receptor type-1 (mouse)
def: "A TGF-beta receptor type-1 that is encoded in the genome of mouse." [OMA:Q64729, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tgfbr1" RELATED Gene-based [UniProtKB:Q64729]
synonym: "mTGFBR1" EXACT PRO-short-label [PRO:DNx]
synonym: "ESK2 (mouse)" EXACT [UniProtKB:Q64729]
synonym: "TGFR-1 (mouse)" EXACT [UniProtKB:Q64729]
synonym: "TbetaR-I (mouse)" EXACT [UniProtKB:Q64729]
synonym: "TGF-beta receptor type I (mouse)" EXACT [UniProtKB:Q64729]
synonym: "transforming growth factor-beta receptor type I (mouse)" EXACT [UniProtKB:Q64729]
xref: UniProtKB:Q64729
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000047 ! TGF-beta receptor type-1
relationship: has_gene_template MGI:98728 ! Tgfbr1 (mouse)

[Term]
id: PR:000000194
name: TGF-beta receptor type-1 sequence variant R487P (human)
def: "A TGF-beta receptor type-1 (human) that has a Pro residue at the position equivalent to Arg-487 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Arg-487, CHEBI:50342." [PMID:15731757, PMID:16928994, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:R487P" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Arg-487, CHEBI:50342" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 7 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_022347
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000195
name: TGF-beta receptor type-1 sequence variant R487E (human)
def: "A TGF-beta receptor type-1 (human) that has a Glu residue at the position equivalent to Arg-487 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Arg-487, CHEBI:29972." [PMID:16791849, PMID:16928994, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:R487E" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Arg-487, CHEBI:29972" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 8 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_029484
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000192
name: TGF-beta receptor type-1 sequence variant M318R (human)
def: "A TGF-beta receptor type-1 (human) that has an Arg residue at the position equivalent to Met-318 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Met-318, CHEBI:29952." [PMID:15731757, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:M318R" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Met-318, CHEBI:29952" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 5 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_022345
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000193
name: TGF-beta receptor type-1 sequence variant D400G (human)
def: "A TGF-beta receptor type-1 (human) that has a Gly residue at the position equivalent to Asp-400 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Asp-400, CHEBI:29947." [PMID:15731757, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:D400G" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Asp-400, CHEBI:29947" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 6 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_022346
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000190
name: TGF-beta receptor type-1 sequence variant S241L (human)
def: "A TGF-beta receptor type-1 (human) that has a Leu residue at the position equivalent to Ser-241 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Ser-241, CHEBI:30006." [PMID:16596670, PMID:16791849, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:S241L" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Ser-241, CHEBI:30006" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 3 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_029482
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000191
name: TGF-beta receptor type-1 sequence variant N267H (human)
def: "A TGF-beta receptor type-1 (human) that has a His residue at the position equivalent to Asn-267 of the amino acid sequence represented by UniProtKB:P36897-1. Example: UniProtKB:P36897-1, Asn-267, CHEBI:29979." [PMID:16791849, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTGFBR1/var:N267H" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36897-1, Asn-267, CHEBI:29979" NARROW PRO-proteoform-std [PRO:DAN]
synonym: "TGF-beta receptor type-1 sequence variant 4 (human)" EXACT [PRO:DNx]
xref: UniProtKB_VAR:VAR_029483
is_a: PR:P36897 ! TGF-beta receptor type-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens