[Term] id: PR:P37023-1 name: serine/threonine-protein kinase receptor R3 isoform 1 (human) def: "A serine/threonine-protein kinase receptor R3 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hACVRL1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P37023-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000316 ! serine/threonine-protein kinase receptor R3 isoform 1 [Term] id: PR:000000126 name: serine/threonine-protein kinase receptor R3 def: "A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVRL1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "ALK1" RELATED Gene-based [] synonym: "SKR3" EXACT [] synonym: "ALK-1" EXACT [] synonym: "TSR-I" RELATED [] synonym: "ACVRL1" EXACT PRO-short-label [PRO:DNx] synonym: "ACVRLK1" RELATED Gene-based [] synonym: "activin receptor-like kinase 1" EXACT [] synonym: "TGF-B superfamily receptor type I" RELATED [] xref: IUPHARobj:1784 is_a: PR:000000006 ! TGF-beta superfamily receptor type-1 [Term] id: PR:Q61288-1 name: serine/threonine-protein kinase receptor R3 isoform 1 (mouse) def: "A serine/threonine-protein kinase receptor R3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA] comment: Category=organism-sequence. synonym: "mACVRL1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q61288-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000316 ! serine/threonine-protein kinase receptor R3 isoform 1 [Term] id: PR:P37023 name: serine/threonine-protein kinase receptor R3 (human) def: "A serine/threonine-protein kinase receptor R3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P37023] comment: Category=organism-gene. synonym: "ALK1" RELATED Gene-based [UniProtKB:P37023] synonym: "ACVRL1" RELATED Gene-based [UniProtKB:P37023] synonym: "ACVRLK1" RELATED Gene-based [UniProtKB:P37023] synonym: "hACVRL1" EXACT PRO-short-label [PRO:DNx] synonym: "SKR3 (human)" EXACT [UniProtKB:P37023] synonym: "ALK-1 (human)" EXACT [UniProtKB:P37023] synonym: "TSR-I (human)" BROAD [UniProtKB:P37023] synonym: "activin receptor-like kinase 1 (human)" EXACT [UniProtKB:P37023] synonym: "TGF-B superfamily receptor type I (human)" BROAD [UniProtKB:P37023] xref: DTO:03100011 xref: UniProtKB:P37023 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000126 ! serine/threonine-protein kinase receptor R3 relationship: has_gene_template HGNC:175 ! ACVRL1 (human) [Term] id: PR:Q61288 name: serine/threonine-protein kinase receptor R3 (mouse) def: "A serine/threonine-protein kinase receptor R3 that is encoded in the genome of mouse." [OMA:Q61288, PRO:DNx] comment: Category=organism-gene. synonym: "Alk-1" RELATED Gene-based [UniProtKB:Q61288] synonym: "Acvrl1" RELATED Gene-based [UniProtKB:Q61288] synonym: "Acvrlk1" RELATED Gene-based [UniProtKB:Q61288] synonym: "mACVRL1" EXACT PRO-short-label [PRO:DNx] synonym: "SKR3 (mouse)" EXACT [UniProtKB:Q61288] synonym: "ALK-1 (mouse)" EXACT [UniProtKB:Q61288] synonym: "TSR-I (mouse)" RELATED [UniProtKB:Q61288] synonym: "activin receptor-like kinase 1 (mouse)" EXACT [UniProtKB:Q61288] synonym: "TGF-B superfamily receptor type I (mouse)" RELATED [UniProtKB:Q61288] xref: UniProtKB:Q61288 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000126 ! serine/threonine-protein kinase receptor R3 relationship: has_gene_template MGI:1338946 ! Acvrl1 (mouse) [Term] id: PR:000000338 name: serine/threonine-protein kinase receptor R3 sequence variant D397G (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Gly residue at the position equivalent to Asp-397 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Asp-397, CHEBI:29947." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:D397G" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Asp-397, CHEBI:29947" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 29 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026804 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000339 name: serine/threonine-protein kinase receptor R3 sequence variant C51Y (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Tyr residue at the position equivalent to Cys-51 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Cys-51, CHEBI:46858." [PMID:11170071, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:C51Y" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Cys-51, CHEBI:46858" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 3 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006205 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000336 name: serine/threonine-protein kinase receptor R3 sequence variant E379K (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Lys residue at the position equivalent to Glu-379 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Glu-379, CHEBI:29967." [PMID:15024723, PMID:15712270, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:E379K" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Glu-379, CHEBI:29967" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 27 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026803 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000337 name: serine/threonine-protein kinase receptor R3 sequence variant M376R (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Arg residue at the position equivalent to Met-376 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Met-376, CHEBI:29952." [PMID:8640225, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:M376R" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Met-376, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 28 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006212 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000334 name: serine/threonine-protein kinase receptor R3 sequence variant R374W (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Trp residue at the position equivalent to Arg-374 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-374, CHEBI:29954." [PMID:11170071, PMID:14684682, PMID:15712270, PMID:9245985, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R374W" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-374, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 25 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006211 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000335 name: serine/threonine-protein kinase receptor R3 sequence variant P378L (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Leu residue at the position equivalent to Pro-378 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Pro-378, CHEBI:30006." [PMID:14684682, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:P378L" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Pro-378, CHEBI:30006" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 26 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026802 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000332 name: serine/threonine-protein kinase receptor R3 sequence variant A347P (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Pro residue at the position equivalent to Ala-347 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Ala-347, CHEBI:50342." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:A347P" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Ala-347, CHEBI:50342" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 23 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026799 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000333 name: serine/threonine-protein kinase receptor R3 sequence variant R374Q (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Gln residue at the position equivalent to Arg-374 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-374, CHEBI:30011." [PMID:14684682, PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R374Q" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-374, CHEBI:30011" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 24 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026800 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000330 name: serine/threonine-protein kinase receptor R3 sequence variant L337P (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Pro residue at the position equivalent to Leu-337 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Leu-337, CHEBI:50342." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:L337P" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Leu-337, CHEBI:50342" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 21 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026797 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000331 name: serine/threonine-protein kinase receptor R3 sequence variant C344Y (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Tyr residue at the position equivalent to Cys-344 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Cys-344, CHEBI:46858." [PMID:10767348, PMID:14684682, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:C344Y" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Cys-344, CHEBI:46858" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 22 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026798 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000358 name: serine/threonine-protein kinase receptor R3 sequence variant N96D (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Asp residue at the position equivalent to Asn-96 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Asn-96, CHEBI:29958." [PMID:10694922, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:N96D" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Asn-96, CHEBI:29958" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 7 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006208 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000359 name: serine/threonine-protein kinase receptor R3 sequence variant D179A (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Ala residue at the position equivalent to Asp-179 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Asp-179, CHEBI:46217." [PMID:14684682, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:D179A" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Asp-179, CHEBI:46217" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 8 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026787 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000316 name: serine/threonine-protein kinase receptor R3 isoform 1 def: "A serine/threonine-protein kinase receptor R3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37023-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "ALK1" RELATED [] synonym: "ACVRL1/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "Serine/threonine-protein kinase receptor R3" RELATED [] is_a: PR:000000126 ! serine/threonine-protein kinase receptor R3 [Term] id: PR:000000317 name: serine/threonine-protein kinase receptor R3 sequence variant G48R (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Arg residue at the position equivalent to Gly-48 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Gly-48, CHEBI:29952." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:G48R" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Gly-48, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 1 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026785 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000318 name: serine/threonine-protein kinase receptor R3 sequence variant E215K (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Lys residue at the position equivalent to Glu-215 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Glu-215, CHEBI:29967." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:E215K" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Glu-215, CHEBI:29967" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 10 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026789 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000319 name: serine/threonine-protein kinase receptor R3 sequence variant H222del (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a single-residue deletion at the position equivalent to His-222 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, 22-221, 223-503." [PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:H222del" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, 22-221, 223-503" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 11 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006209 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000356 name: serine/threonine-protein kinase receptor R3 sequence variant R67W (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Trp residue at the position equivalent to Arg-67 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-67, CHEBI:29954." [PMID:15712270, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R67W" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-67, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 5 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026786 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000357 name: serine/threonine-protein kinase receptor R3 sequence variant C77W (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Trp residue at the position equivalent to Cys-77 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Cys-77, CHEBI:29954." [PMID:10694922, PMID:14684682, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:C77W" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Cys-77, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 6 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006207 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000350 name: serine/threonine-protein kinase receptor R3 sequence variant R67Q (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Gln residue at the position equivalent to Arg-67 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-67, CHEBI:30011." [PMID:14684682, PMID:9245985, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R67Q" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-67, CHEBI:30011" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 4 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006206 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000351 name: serine/threonine-protein kinase receptor R3 sequence variant R479L (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Leu residue at the position equivalent to Arg-479 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-479, CHEBI:30006." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R479L" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-479, CHEBI:30006" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 40 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026813 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000352 name: serine/threonine-protein kinase receptor R3 sequence variant A482V (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Val residue at the position equivalent to Ala-482 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Ala-482, CHEBI:30015." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:A482V" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Ala-482, CHEBI:30015" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 41 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026814 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000353 name: serine/threonine-protein kinase receptor R3 sequence variant R484W (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Trp residue at the position equivalent to Arg-484 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-484, CHEBI:29954." [PMID:11484689, PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R484W" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-484, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 42 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026815 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P80203 name: serine/threonine-protein kinase receptor R3 (rat) def: "A serine/threonine-protein kinase receptor R3 that is encoded in the genome of rat." [OMA:P80203, PANTHER:PTHR23255:SF14, PRO:DNx] comment: Category=organism-gene. synonym: "Acvrl1" RELATED Gene-based [UniProtKB:P80203] synonym: "Acvrlk1" RELATED Gene-based [UniProtKB:P80203] synonym: "rACVRL1" EXACT PRO-short-label [PRO:DNx] synonym: "SKR3 (rat)" EXACT [UniProtKB:P80203] synonym: "TSR-I (rat)" RELATED [UniProtKB:P80203] synonym: "TGF-B superfamily receptor type I (rat)" RELATED [UniProtKB:P80203] xref: UniProtKB:P80203 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000000126 ! serine/threonine-protein kinase receptor R3 relationship: has_gene_template RGD:2029 ! Acvrl1 (rat) [Term] id: PR:000000354 name: serine/threonine-protein kinase receptor R3 sequence variant K487T (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Thr residue at the position equivalent to Lys-487 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Lys-487, CHEBI:30013." [PMID:14684682, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:K487T" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Lys-487, CHEBI:30013" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 43 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026816 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000355 name: serine/threonine-protein kinase receptor R3 sequence variant GA48/49EP (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has Glu and Pro residues at positions equivalent to Gly-48 and Ala-49 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Gly-48, CHEBI:29972|Ala-49, CHEBI:46217." [PMID:10767348, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:GA48/49EP" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Gly-48, CHEBI:29972|Ala-49, CHEBI:46217" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 44 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026784 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000329 name: serine/threonine-protein kinase receptor R3 sequence variant S333I (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Ile residue at the position equivalent to Ser-333 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Ser-333, CHEBI:30009." [PMID:10767348, PMID:14684682, PMID:9245985, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:S333I" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Ser-333, CHEBI:30009" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 20 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006210 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000328 name: serine/threonine-protein kinase receptor R3 sequence variant W50C (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Cys residue at the position equivalent to Trp-50 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Trp-50, CHEBI:29950." [PMID:10767348, PMID:14684682, PMID:9245985, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:W50C" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Trp-50, CHEBI:29950" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 2 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006204 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000321 name: serine/threonine-protein kinase receptor R3 sequence variant G223R (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Arg residue at the position equivalent to Gly-223 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Gly-223, CHEBI:29952." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:G223R" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Gly-223, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 13 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026790 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000320 name: serine/threonine-protein kinase receptor R3 sequence variant S233del (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a single-residue deletion at the position equivalent to Ser-233 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, 22-232, 234-503." [PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:S233del" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, 22-232, 234-503" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 12 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026792 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000323 name: serine/threonine-protein kinase receptor R3 sequence variant D254del (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a single-residue deletion at the position equivalent to Asp-254 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, 22-253, 255-503." [PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:D254del" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, 22-253, 255-503" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 15 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026793 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000322 name: serine/threonine-protein kinase receptor R3 sequence variant K229R (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Arg residue at the position equivalent to Lys-229 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Lys-229, CHEBI:29952." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:K229R" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Lys-229, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 14 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026791 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000325 name: serine/threonine-protein kinase receptor R3 sequence variant L285F (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Phe residue at the position equivalent to Leu-285 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Leu-285, CHEBI:29997." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:L285F" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Leu-285, CHEBI:29997" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 17 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026794 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000324 name: serine/threonine-protein kinase receptor R3 sequence variant M376V (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Val residue at the position equivalent to Met-376 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Met-376, CHEBI:30015." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:M376V" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Met-376, CHEBI:30015" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 16 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026801 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000327 name: serine/threonine-protein kinase receptor R3 sequence variant H314Y (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Tyr residue at the position equivalent to His-314 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, His-314, CHEBI:46858." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:H314Y" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, His-314, CHEBI:46858" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 19 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026796 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000326 name: serine/threonine-protein kinase receptor R3 sequence variant A306P (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Pro residue at the position equivalent to Ala-306 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Ala-306, CHEBI:50342." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:A306P" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Ala-306, CHEBI:50342" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 18 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026795 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000360 name: serine/threonine-protein kinase receptor R3 sequence variant G211D (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Asp residue at the position equivalent to Gly-211 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Gly-211, CHEBI:29958." [PMID:14684682, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:G211D" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Gly-211, CHEBI:29958" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 9 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026788 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000349 name: serine/threonine-protein kinase receptor R3 sequence variant F425del (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a single-residue deletion at the position equivalent to Phe-425 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, 22-423, 425-503." [PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:F425del" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, 22-423, 425-503" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 39 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026812 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000348 name: serine/threonine-protein kinase receptor R3 sequence variant F425V (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Val residue at the position equivalent to Phe-425 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Phe-425, CHEBI:30015." [PMID:15712270, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:F425V" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Phe-425, CHEBI:30015" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 38 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026811 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000347 name: serine/threonine-protein kinase receptor R3 sequence variant F425L (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Leu residue at the position equivalent to Phe-425 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Phe-425, CHEBI:30006." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:F425L" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Phe-425, CHEBI:30006" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 37 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026810 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000346 name: serine/threonine-protein kinase receptor R3 sequence variant P424T (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Thr residue at the position equivalent to Pro-424 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Pro-424, CHEBI:30013." [PMID:9245985, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:P424T" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Pro-424, CHEBI:30013" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 36 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006214 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000345 name: serine/threonine-protein kinase receptor R3 sequence variant R411W (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Trp residue at the position equivalent to Arg-411 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-411, CHEBI:29954." [PMID:11484689, PMID:15024723, PMID:15712270, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R411W" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-411, CHEBI:29954" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 35 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026809 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000344 name: serine/threonine-protein kinase receptor R3 sequence variant R411Q (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Gln residue at the position equivalent to Arg-411 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-411, CHEBI:30011." [PMID:14684682, PMID:15024723, PMID:8640225, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R411Q" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-411, CHEBI:30011" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 34 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_006213 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000343 name: serine/threonine-protein kinase receptor R3 sequence variant R411P (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Pro residue at the position equivalent to Arg-411 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Arg-411, CHEBI:50342." [PMID:15024723, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:R411P" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Arg-411, CHEBI:50342" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 33 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026808 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000342 name: serine/threonine-protein kinase receptor R3 sequence variant E407D (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Asp residue at the position equivalent to Glu-407 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Glu-407, CHEBI:29958." [PMID:10767348, PMID:15712270, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:E407D" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Glu-407, CHEBI:29958" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 32 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026807 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000341 name: serine/threonine-protein kinase receptor R3 sequence variant W399S (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has a Ser residue at the position equivalent to Trp-399 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Trp-399, CHEBI:29999." [PMID:11170071, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:W399S" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Trp-399, CHEBI:29999" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 31 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026806 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000000340 name: serine/threonine-protein kinase receptor R3 sequence variant I398N (human) def: "A serine/threonine-protein kinase receptor R3 (human) that has an Asn residue at the position equivalent to Ile-398 of the amino acid sequence represented by UniProtKB:P37023. UniProtKB:P37023, Ile-398, CHEBI:50347." [PMID:11170071, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVRL1/var:I398N" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P37023, Ile-398, CHEBI:50347" EXACT PRO-proteoform-std [PRO:DAN] synonym: "serine/threonine-protein kinase receptor R3 sequence variant 30 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_026805 is_a: PR:P37023 ! serine/threonine-protein kinase receptor R3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens