[Term]
id: PR:P49001
name: bone morphogenetic protein 2 (rat)
def: "A bone morphogenetic protein 2 that is encoded in the genome of rat." [PANTHER:PTHR11848:SF50, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bmp2" RELATED Gene-based [UniProtKB:P49001]
synonym: "Bmp-2" RELATED Gene-based [UniProtKB:P49001]
synonym: "rBMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "BMP-2 (rat)" EXACT [UniProtKB:P49001]
synonym: "BMP-2A (rat)" EXACT [UniProtKB:P49001]
synonym: "bone morphogenetic protein 2A (rat)" EXACT [UniProtKB:P49001]
xref: UniProtKB:P49001
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000164 ! bone morphogenetic protein 2
relationship: has_gene_template RGD:2211 ! Bmp2 (rat)

[Term]
id: PR:P12643
name: bone morphogenetic protein 2 (human)
def: "A bone morphogenetic protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12643]
comment: Category=organism-gene.
synonym: "BMP2" RELATED Gene-based [UniProtKB:P12643]
synonym: "BMP2A" RELATED Gene-based [UniProtKB:P12643]
synonym: "hBMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "BMP-2 (human)" EXACT [UniProtKB:P12643]
synonym: "BMP-2A (human)" EXACT [UniProtKB:P12643]
synonym: "bone morphogenetic protein 2A (human)" EXACT [UniProtKB:P12643]
xref: UniProtKB:P12643
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000164 ! bone morphogenetic protein 2
relationship: has_gene_template HGNC:1069 ! BMP2 (human)

[Term]
id: PR:000021898
name: bone morphogenetic protein 2 isoform 1, signal peptide removed form
def: "A bone morphogenetic protein 2 isoform 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "BMP2/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000385 ! bone morphogenetic protein 2 isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000046491
name: bone morphogenetic protein 2, signal peptide removed form (human)
def: "A bone morphogenetic protein 2 (human) that has had the signal peptide removed. UniProtKB:P12643, 24-396." [PRO:DNx, Reactome:R-HSA-2396130]
comment: Category=organism-modification.
synonym: "hBMP2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12643, 24-396" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2396130 "PR:000046491 located_in GO:0005576"
intersection_of: PR:P12643 ! bone morphogenetic protein 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000018286
name: bone morphogenetic protein 2 proteolytic cleavage product
def: "A bone morphogenetic protein 2 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "BMP2/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000000164 ! bone morphogenetic protein 2

[Term]
id: PR:P12643-1
name: bone morphogenetic protein 2 isoform 1 (human)
def: "A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hBMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12643-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000385 ! bone morphogenetic protein 2 isoform 1

[Term]
id: PR:000026336
name: bone morphogenetic protein 2 isoform 1, mature form (human)
def: "A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]
comment: Category=organism-modification.
synonym: "PRO_0000033825" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hBMP2/iso:1/mature" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12643-1, 283-396" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-201456 "PR:000026336 located_in GO:0005576"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000608 ! bone morphogenetic protein 2 isoform 1, mature form

[Term]
id: PR:000000164
name: bone morphogenetic protein 2
def: "A bone morphogenetic protein that is a translation product of the human BMP2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "BMP2" EXACT PRO-short-label [PRO:DAN]
synonym: "BMP-2" EXACT []
synonym: "BMP2A" RELATED Gene-based []
synonym: "BMP-2A" EXACT []
synonym: "bone morphogenetic protein 2A" EXACT []
is_a: PR:000000034 ! bone morphogenetic protein

[Term]
id: PR:000036510
name: bone morphogenetic protein 2 isoform 1, mature form (mouse)
def: "A bone morphogenetic protein 2 isoform 1, mature form in mouse. UniProtKB:P21274-1, 281-394." [PMID:14623234, PMID:15110716, PMID:15565649, PMID:16109715, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000033827" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "mBMP2/iso:1/mature" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P21274-1, 281-394" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000608 ! bone morphogenetic protein 2 isoform 1, mature form

[Term]
id: PR:000000608
name: bone morphogenetic protein 2 isoform 1, mature form
def: "A bone morphogenetic protein 2 isoform 1 that has had the signal peptide and propeptide removed." [PMID:10074410]
comment: Category=modification.
synonym: "BMP2/iso:1/mature" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000385 ! bone morphogenetic protein 2 isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide
intersection_of: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:P21274
name: bone morphogenetic protein 2 (mouse)
def: "A bone morphogenetic protein 2 that is encoded in the genome of mouse." [OMA:P21274, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bmp2" RELATED Gene-based [UniProtKB:P21274]
synonym: "Bmp-2" RELATED Gene-based [UniProtKB:P21274]
synonym: "mBMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "BMP-2 (mouse)" EXACT [UniProtKB:P21274]
synonym: "BMP-2A (mouse)" EXACT [UniProtKB:P21274]
synonym: "bone morphogenetic protein 2A (mouse)" EXACT [UniProtKB:P21274]
xref: UniProtKB:P21274
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000164 ! bone morphogenetic protein 2
relationship: has_gene_template MGI:88177 ! Bmp2 (mouse)

[Term]
id: PR:P21274-1
name: bone morphogenetic protein 2 isoform 1 (mouse)
def: "A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mBMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P21274-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000385 ! bone morphogenetic protein 2 isoform 1

[Term]
id: PR:000000385
name: bone morphogenetic protein 2 isoform 1
def: "A bone morphogenetic protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12643-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "BMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000164 ! bone morphogenetic protein 2

[Term]
id: PR:000050190
name: bone morphogenetic protein 2 isoform m2 (mouse)
def: "A bone morphogenetic protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21274-1, 59-394. This isoform is encoded from an alternative downstream start codon relative to that encoding for isoform 1. UniProtKB:P21274-1, 59-394." [PMID:20230640, PMID:30700748, PRO:HJD]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:30700748).
synonym: "nBmp2" EXACT [PMID:30700748]
synonym: "mBMP2/iso:m2" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P21274-1, 59-394" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P21274 ! bone morphogenetic protein 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus