[Term]
id: PR:000000992
name: voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1
def: "A voltage-gated potassium channel KCNC1 isoform Long phosphorylated form in which the phosphorylation occurs by the action of PKC at the Ser residue within the DSKL motif located in the C-terminal tail. In resting neurons, basal phosphorylation at this site decreases Kv3.1 channel current, reducing neuronal ability to follow high frequency stimulation. Example: UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659]
comment: Category=modification.
synonym: "KCNC1/iso:2/Phos:1" EXACT [PRO:DNx]
synonym: "KCNC1/iso:Long/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1" EXACT [PRO:DNx]
is_a: PR:000000986 ! voltage-gated potassium channel KCNC1 isoform Long phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000000940
name: voltage-gated potassium channel KCNC1 isoform Long
def: "A voltage-gated potassium channel KCNC1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25122-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "Kv3.1b" EXACT []
synonym: "KCNC1/iso:Long" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel KCNC1 isoform 2" EXACT [PRO:DNx]
is_a: PR:000000781 ! voltage-gated potassium channel KCNC1

[Term]
id: PR:P15388-3
name: potassium voltage-gated channel subfamily C member 1, isoform Long (mouse)
def: "A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD, RefSeq:NP_001106210]
comment: Category=organism-sequence.
synonym: "KV4 (mouse)" EXACT [UniProtKB:P15388]
synonym: "KV3.1b (mouse)" EXACT []
synonym: "mKCNC1/iso:Long" EXACT PRO-short-label [PRO:DNx]
synonym: "Kcnc1 isoform 3 (mouse)" EXACT [PRO:DNx]
xref: UniProtKB:P15388-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000940 ! voltage-gated potassium channel KCNC1 isoform Long

[Term]
id: PR:000000986
name: voltage-gated potassium channel KCNC1 isoform Long phosphorylated form
def: "A voltage-gated potassium channel KCNC1 isoform Long that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "KCNC1/iso:2/PhosRes+" EXACT [PRO:DNx]
synonym: "KCNC1/iso:Long/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel KCNC1 isoform 2 phosphorylated form" EXACT [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000000940 ! voltage-gated potassium channel KCNC1 isoform Long

[Term]
id: PR:000000939
name: voltage-gated potassium channel KCNC1 isoform Short
def: "A voltage-gated potassium channel KCNC1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48547-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "Kv3.1a" RELATED []
synonym: "KCNC1/iso:Short" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel KCNC1 isoform 1" EXACT [PRO:DNx]
is_a: PR:000000781 ! voltage-gated potassium channel KCNC1

[Term]
id: PR:P48547-1
name: potassium voltage-gated channel subfamily C member 1 isoform 1 (human)
def: "A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hKCNC1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48547-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000939 ! voltage-gated potassium channel KCNC1 isoform Short

[Term]
id: PR:P25122
name: potassium voltage-gated channel subfamily C member 1 (rat)
def: "A voltage-gated potassium channel KCNC1 that is encoded in the genome of rat." [OMA:P25122, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kcnc1" RELATED Gene-based [UniProtKB:P25122]
synonym: "rKCNC1" EXACT PRO-short-label [PRO:DNx]
synonym: "NGK2 (rat)" EXACT [UniProtKB:P25122]
synonym: "RAW2 (rat)" EXACT [UniProtKB:P25122]
synonym: "voltage-gated potassium channel subunit Kv4 (rat)" EXACT [UniProtKB:P25122]
synonym: "voltage-gated potassium channel subunit Kv3.1 (rat)" EXACT [UniProtKB:P25122]
xref: UniProtKB:P25122
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000781 ! voltage-gated potassium channel KCNC1
relationship: has_gene_template RGD:2955 ! Kcnc1 (rat)

[Term]
id: PR:000000781
name: voltage-gated potassium channel KCNC1
def: "A shaw-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNC1 gene or a 1:1 ortholog thereof. They contain an ATM motif at the C-terminus, following the S6 segment that allows interaction with axonal targeting machinery when exposed." [PRO:CNA]
comment: Category=gene.
synonym: "NGK2" EXACT []
synonym: "RAW2" EXACT []
synonym: "KCNC1" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel subunit Kv4" EXACT []
synonym: "voltage-gated potassium channel subunit Kv3.1" EXACT []
xref: IUPHARobj:548
is_a: PR:000000711 ! shaw-related voltage-gated potassium channel alpha subunit

[Term]
id: PR:P48547
name: potassium voltage-gated channel subfamily C member 1 (human)
def: "A voltage-gated potassium channel KCNC1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P48547]
comment: Category=organism-gene.
synonym: "KCNC1" RELATED Gene-based [UniProtKB:P48547]
synonym: "hKCNC1" EXACT PRO-short-label [PRO:DNx]
synonym: "NGK2 (human)" EXACT [UniProtKB:P48547]
synonym: "voltage-gated potassium channel subunit Kv4 (human)" EXACT [UniProtKB:P48547]
synonym: "voltage-gated potassium channel subunit Kv3.1 (human)" EXACT [UniProtKB:P48547]
xref: Reactome:R-HSA-977463 "PR:P48547 located_in GO:0005886"
xref: DTO:01100189
xref: UniProtKB:P48547
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000781 ! voltage-gated potassium channel KCNC1
relationship: has_gene_template HGNC:6233 ! KCNC1 (human)

[Term]
id: PR:000036575
name: voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 (rat)
def: "A voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1 in rat. UniProtKB:P25122-1, Ser-503, MOD:00046." [PMID:16595659, PRO:CNA]
comment: Category=organism-modification. Kinase=("PKC"; PR:000045382; Ser-503).
synonym: "rKCNC1/iso:2/Phos:1" EXACT [PRO:DNx]
synonym: "rKCNC1/iso:Long/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P25122-1, Ser-503, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1 (rat)" EXACT [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000992 ! voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000045386
name: voltage-gated potassium channel KCNC1 isoform Long unphosphorylated 1 (rat)
def: "A potassium voltage-gated channel subfamily C member 1 isoform Long (rat) that lacks phosphorylation on Ser-503. UniProtKB:P25122-1, Ser-503, PR:000026291." [PMID:16595659, PRO:CNA]
comment: Category=organism-modification.
synonym: "rKCNC1/iso:2/UnPhos:1" EXACT [PRO:DNx]
synonym: "rKCNC1/iso:Long/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P25122-1, Ser-503, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P25122-1 ! potassium voltage-gated channel subfamily C member 1 isoform Long (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P48547-2
name: potassium voltage-gated channel subfamily C member 1 isoform h2 (human)
def: "A potassium voltage-gated channel subfamily C member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48547-2." [PRO:DNx, UniProtKB:P48547]
comment: Category=organism-sequence.
synonym: "hKCNC1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P48547-2
is_a: PR:P48547 ! potassium voltage-gated channel subfamily C member 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P15388-1
name: potassium voltage-gated channel subfamily C member 1, isoform Short (mouse)
def: "A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of mouse." [PMID:2599109, PRO:HJD]
comment: Category=organism-sequence.
synonym: "KV3.1a (mouse)" EXACT []
synonym: "mKCNC1/iso:Short" EXACT PRO-short-label [PRO:DNx]
synonym: "Kcnc1 isoform 1 (mouse)" EXACT [PRO:DNx]
synonym: "potassium voltage-gated channel subfamily C member 1, isoform KV3.1 (mouse)" EXACT [PRO:DNx]
xref: UniProtKB:P15388-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000939 ! voltage-gated potassium channel KCNC1 isoform Short

[Term]
id: PR:P15388
name: potassium voltage-gated channel subfamily C member 1 (mouse)
def: "A voltage-gated potassium channel KCNC1 that is encoded in the genome of mouse." [OMA:P15388, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kcnc1" RELATED Gene-based [UniProtKB:P15388]
synonym: "mKCNC1" EXACT PRO-short-label [PRO:DNx]
synonym: "NGK2 (mouse)" EXACT [UniProtKB:P15388]
synonym: "voltage-gated potassium channel subunit Kv4 (mouse)" EXACT [UniProtKB:P15388]
synonym: "voltage-gated potassium channel subunit Kv3.1 (mouse)" EXACT [UniProtKB:P15388]
xref: UniProtKB:P15388
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000781 ! voltage-gated potassium channel KCNC1
relationship: has_gene_template MGI:96667 ! Kcnc1 (mouse)

[Term]
id: PR:P25122-1
name: potassium voltage-gated channel subfamily C member 1 isoform Long (rat)
def: "A voltage-gated potassium channel KCNC1 isoform Long that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "rKCNC1/iso:Long" EXACT PRO-short-label [PRO:DNx]
synonym: "Kcnc1 isoform 1 (rat)" EXACT [PRO:DNx]
synonym: "potassium voltage-gated channel subfamily C member 1 isoform 1 (rat)" EXACT [PRO:DNx]
xref: UniProtKB:P25122-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000940 ! voltage-gated potassium channel KCNC1 isoform Long

[Term]
id: PR:P25122-2
name: potassium voltage-gated channel subfamily C member 1 isoform Short (rat)
def: "A voltage-gated potassium channel KCNC1 isoform Short that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "rKCNC1/iso:Short" EXACT PRO-short-label [PRO:DNx]
synonym: "Kcnc1 isoform 2 (rat)" EXACT [PRO:DNx]
synonym: "potassium voltage-gated channel subfamily C member 1 isoform 2 (rat)" EXACT [UniProtKB:P25122]
xref: UniProtKB:P25122-2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000939 ! voltage-gated potassium channel KCNC1 isoform Short