[Term]
id: PR:000000809
name: voltage-gated potassium channel subunit KCNA10
def: "A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA10 gene or a 1:1 ortholog thereof. It is a subunit of the Kv1.8 channel is a delayed rectifier channel that may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential. It is regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. It can coassemble with other Kv1 subunits." [PMID:10836990]
comment: Category=gene.
synonym: "KCNA10" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel subunit Kv1.8" EXACT []
xref: IUPHARobj:545
is_a: PR:000000709 ! shaker-related voltage-gated potassium channel alpha subunit

[Term]
id: PR:Q16322-1
name: potassium voltage-gated channel subfamily A member 10 isoform 1 (human)
def: "A voltage-gated potassium channel subunit KCNA10 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hKCNA10/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16322-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000971 ! voltage-gated potassium channel subunit KCNA10 isoform 1

[Term]
id: PR:Q16322
name: potassium voltage-gated channel subfamily A member 10 (human)
def: "A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of human." []
comment: Category=organism-gene.
synonym: "KCNA10" RELATED Gene-based [UniProtKB:Q16322]
synonym: "hKCNA10" EXACT PRO-short-label [PRO:DNx]
synonym: "voltage-gated potassium channel subunit Kv1.8 (human)" EXACT [UniProtKB:Q16322]
xref: Reactome:R-HSA-977480 "PR:Q16322 located_in GO:0005886"
xref: DTO:01100168
xref: UniProtKB:Q16322
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000809 ! voltage-gated potassium channel subunit KCNA10
relationship: has_gene_template HGNC:6219 ! KCNA10 (human)