[Term]
id: PR:P22646
name: T-cell surface glycoprotein CD3 epsilon chain (mouse)
def: "A CD3 epsilon that is encoded in the genome of mouse." [OMA:P22646, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cd3e" RELATED Gene-based [UniProtKB:P22646]
synonym: "mCD3E" EXACT PRO-short-label [PRO:DNx]
synonym: "CD3e (mouse)" EXACT [UniProtKB:P22646]
synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)" EXACT [UniProtKB:P22646]
xref: UniProtKB:P22646
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001020 ! CD3 epsilon
relationship: has_gene_template MGI:88332 ! Cd3e (mouse)

[Term]
id: PR:000025777
name: CD3 epsilon isoform 1, signal peptide removed phosphorylated 1 (human)
def: "A CD3 epsilon isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P07766-1, 23-207, Tyr-188/Tyr-199, MOD:00048." [PRO:DNx, UniProtKB:P07766]
comment: Category=organism-modification.
synonym: "hCD3E/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "CD3 epsilon with phosphorylated ITAM" EXACT []
synonym: "PRO_0000014607, Tyr-188/Tyr-199, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P07766-1, 23-207, Tyr-188/Tyr-199, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-202228 "PR:000025777 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025776 ! CD3 epsilon isoform 1, signal peptide removed phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000001020
name: CD3 epsilon
def: "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=CL.
synonym: "T3E" RELATED Gene-based []
synonym: "CD3E" EXACT PRO-short-label [PRO:DNx]
synonym: "CD3e" EXACT []
synonym: "T-cell surface antigen T3/Leu-4 epsilon chain" EXACT []
xref: IUPHARobj:2742
is_a: PR:000001018 ! CD3 subunit with immunoglobulin domain

[Term]
id: PR:000025775
name: CD3 epsilon isoform 1
def: "A CD3 epsilon that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07766-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "CD3E/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000001020 ! CD3 epsilon

[Term]
id: PR:P07766-1
name: T-cell surface glycoprotein CD3 epsilon chain isoform 1 (human)
def: "A CD3 epsilon isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCD3E/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07766-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025775 ! CD3 epsilon isoform 1

[Term]
id: PR:000018321
name: CD3 epsilon, signal peptide removed form
def: "A CD3 epsilon that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CD3E/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000001020 ! CD3 epsilon
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000046639
name: T-cell surface glycoprotein CD3 epsilon chain, signal peptide removed form (human)
def: "A T-cell surface glycoprotein CD3 epsilon chain (human) that has had the signal peptide removed. UniProtKB:P07766, 23-207." [PRO:DNx, Reactome:R-HSA-197906]
comment: Category=organism-modification.
synonym: "hCD3E/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014607" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P07766, 23-207" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-197906 "PR:000046639 located_in GO:0005886"
intersection_of: PR:P07766 ! T-cell surface glycoprotein CD3 epsilon chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000025776
name: CD3 epsilon isoform 1, signal peptide removed phosphorylated 1
def: "A CD3 epsilon isoform 1 that has had the signal peptide removed and has been phosphorylated on two Tyr residues within the ITAM domain. Example: UniProtKB:P07766-1, 23-207, Tyr-188/Tyr-199, MOD:00048." [PMID:20516133, PMID:8647168, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "CD3E/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000025775 ! CD3 epsilon isoform 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000026691
name: CD3 epsilon isoform 1, signal peptide removed form
def: "A CD3 epsilon isoform 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CD3E/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000025775 ! CD3 epsilon isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P07766
name: T-cell surface glycoprotein CD3 epsilon chain (human)
def: "A CD3 epsilon that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07766]
comment: Category=organism-gene.
synonym: "T3E" RELATED Gene-based [UniProtKB:P07766]
synonym: "CD3E" RELATED Gene-based [UniProtKB:P07766]
synonym: "hCD3E" EXACT PRO-short-label [PRO:DNx]
synonym: "CD3e (human)" EXACT [UniProtKB:P07766]
synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (human)" EXACT [UniProtKB:P07766]
xref: UniProtKB:P07766
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001020 ! CD3 epsilon
relationship: has_gene_template HGNC:1674 ! CD3E (human)