[Term]
id: PR:000001030
name: erm protein
def: "A protein that contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain, and a charged C-terminal domain. Ezrin, radixin and merlin also contain a polyproline region between the helical and C-terminal domains. The N-terminal domain is highly conserved, and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily. ERM proteins are involved in crosslinking actin filaments with plasma membranes." [InterPro:IPR011259]
comment: Category=family.
xref: PIRSF:PIRSF002305
is_a: PR:000000001 ! protein