[Term]
id: PR:Q9UNQ0
name: broad substrate specificity ATP-binding cassette transporter ABCG2 (human)
def: "A broad substrate specificity ATP-binding cassette transporter ABCG2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9UNQ0]
comment: Category=organism-gene.
synonym: "MXR" RELATED Gene-based [UniProtKB:Q9UNQ0]
synonym: "ABCP" RELATED Gene-based [UniProtKB:Q9UNQ0]
synonym: "BCRP" RELATED Gene-based [UniProtKB:Q9UNQ0]
synonym: "ABCG2" RELATED Gene-based [UniProtKB:Q9UNQ0]
synonym: "BCRP1" RELATED Gene-based [UniProtKB:Q9UNQ0]
synonym: "hABCG2" EXACT PRO-short-label [PRO:DNx]
synonym: "CD338 (human)" EXACT [UniProtKB:Q9UNQ0]
synonym: "CDw338 (human)" EXACT [UniProtKB:Q9UNQ0]
synonym: "urate exporter (human)" EXACT [UniProtKB:Q9UNQ0]
synonym: "breast cancer resistance protein (human)" EXACT [UniProtKB:Q9UNQ0]
synonym: "ATP-binding cassette sub-family G member 2 (human)" EXACT [UniProtKB:Q9UNQ0]
synonym: "mitoxantrone resistance-associated protein (human)" EXACT [UniProtKB:Q9UNQ0]
synonym: "placenta-specific ATP-binding cassette transporter (human)" EXACT [UniProtKB:Q9UNQ0]
xref: UniProtKB:Q9UNQ0
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001283 ! broad substrate specificity ATP-binding cassette transporter ABCG2
relationship: has_gene_template HGNC:74 ! ABCG2 (human)

[Term]
id: PR:000001283
name: broad substrate specificity ATP-binding cassette transporter ABCG2
def: "A protein that is a translation product of the human ABCG2 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "MXR" RELATED Gene-based []
synonym: "ABCP" RELATED Gene-based []
synonym: "BCRP" RELATED Gene-based []
synonym: "ABCG2" EXACT PRO-short-label [PRO:DNx]
synonym: "BCRP1" RELATED Gene-based []
synonym: "CD338" EXACT []
synonym: "CDw338" EXACT []
synonym: "urate exporter" EXACT []
synonym: "breast cancer resistance protein" EXACT []
synonym: "ATP-binding cassette sub-family G member 2" EXACT []
synonym: "breast cancer resistance protein 1 homolog" EXACT []
synonym: "mitoxantrone resistance-associated protein" EXACT []
synonym: "placenta-specific ATP-binding cassette transporter" EXACT []
xref: IUPHARobj:792
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9UNQ0-1
name: broad substrate specificity ATP-binding cassette transporter ABCG2 isoform 1 (human)
def: "A broad substrate specificity ATP-binding cassette transporter ABCG2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UNQ0-1." [PRO:DNx, UniProtKB:Q9UNQ0]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hABCG2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UNQ0-1
is_a: PR:Q9UNQ0 ! broad substrate specificity ATP-binding cassette transporter ABCG2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046088
name: broad substrate specificity ATP-binding cassette transporter ABCG2 phosphorylated 1 (human)
def: "A broad substrate specificity ATP-binding cassette transporter ABCG2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-362 of the amino acid sequence represented by UniProtKB:Q9UNQ0-1. Example: UniProtKB:Q9UNQ0-1, Thr-362, MOD:00047." [PMID:18056989, iPTMnet:Q9UNQ0]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18056989). Status=unreviewed.
synonym: "hABCG2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UNQ0-1, Thr-362, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9UNQ0 ! broad substrate specificity ATP-binding cassette transporter ABCG2 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UNQ0-2
name: broad substrate specificity ATP-binding cassette transporter ABCG2 isoform h2 (human)
def: "A broad substrate specificity ATP-binding cassette transporter ABCG2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UNQ0-2." [PRO:DNx, UniProtKB:Q9UNQ0]
comment: Category=organism-sequence.
synonym: "hABCG2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UNQ0-2
is_a: PR:Q9UNQ0 ! broad substrate specificity ATP-binding cassette transporter ABCG2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens