[Term]
id: PR:000001323
name: autoimmune regulator
def: "A protein that is a translation product of the human AIRE gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "AIRE" EXACT PRO-short-label [PRO:DNx]
synonym: "APECED" RELATED Gene-based []
synonym: "APECED protein" EXACT []
synonym: "APECED protein homolog" EXACT []
synonym: "autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein" EXACT []
synonym: "autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O43918-2
name: autoimmune regulator isoform h2 (human)
def: "An autoimmune regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43918-2." [PRO:DNx, UniProtKB:O43918]
comment: Category=organism-sequence.
synonym: "hAIRE/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "autoimmune regulator isoform AIRE-2 (human)" EXACT [UniProtKB:O43918]
xref: UniProtKB:O43918-2
is_a: PR:O43918 ! autoimmune regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43918-3
name: autoimmune regulator isoform h3 (human)
def: "An autoimmune regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43918-3." [PRO:DNx, UniProtKB:O43918]
comment: Category=organism-sequence.
synonym: "hAIRE/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "autoimmune regulator isoform AIRE-3 (human)" EXACT [UniProtKB:O43918]
xref: UniProtKB:O43918-3
is_a: PR:O43918 ! autoimmune regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43918-1
name: autoimmune regulator isoform h1 (human)
def: "An autoimmune regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43918-1." [PRO:DNx, UniProtKB:O43918]
comment: Category=organism-sequence.
synonym: "hAIRE/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "autoimmune regulator isoform AIRE-1 (human)" EXACT [UniProtKB:O43918]
xref: UniProtKB:O43918-1
is_a: PR:O43918 ! autoimmune regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O43918
name: autoimmune regulator (human)
def: "An autoimmune regulator that is encoded in the genome of human." [PRO:WCB, UniProtKB:O43918]
comment: Category=organism-gene.
synonym: "AIRE" RELATED Gene-based [UniProtKB:O43918]
synonym: "hAIRE" EXACT PRO-short-label [PRO:DNx]
synonym: "APECED" RELATED Gene-based [UniProtKB:O43918]
synonym: "APECED protein (human)" EXACT [UniProtKB:O43918]
synonym: "autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein (human)" EXACT [UniProtKB:O43918]
xref: UniProtKB:O43918
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001323 ! autoimmune regulator
relationship: has_gene_template HGNC:360 ! AIRE (human)

[Term]
id: PR:O43918-4
name: autoimmune regulator isoform h4 (human)
def: "An autoimmune regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43918-4." [PRO:DNx, UniProtKB:O43918]
comment: Category=organism-sequence.
synonym: "hAIRE/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43918-4
is_a: PR:O43918 ! autoimmune regulator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens