[Term]
id: PR:000056196
name: fibroblast growth factor receptor 4 O-glycosylated 1 (human)
def: "A fibroblast growth factor receptor 4 (human) that has been O-glycosylated at the residue equivalent to Thr-260 of the amino acid sequence represented by UniProtKB:P22455-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22455-1, Thr-260, MOD:00005~GNO:G43417UB." [GlyGen:P22455-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hFGFR4/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P22455-1, Thr-260, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P22455 ! fibroblast growth factor receptor 4 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22455-2
name: fibroblast growth factor receptor 4 isoform h2 (human)
def: "A fibroblast growth factor receptor 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22455-2." [PRO:DNx, UniProtKB:P22455]
comment: Category=organism-sequence.
synonym: "hFGFR4/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "fibroblast growth factor receptor 4 isoform Soluble-form (human)" EXACT [UniProtKB:P22455]
xref: UniProtKB:P22455-2
is_a: PR:P22455 ! fibroblast growth factor receptor 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22455-1
name: fibroblast growth factor receptor 4 isoform 1 (human)
def: "A fibroblast growth factor receptor 4 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hFGFR4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22455-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025672 ! fibroblast growth factor receptor 4 isoform 1

[Term]
id: PR:000001451
name: fibroblast growth factor receptor 4
def: "A fibroblast growth factor receptor that is a translation product of the human FGFR4 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "TKF" RELATED Gene-based []
synonym: "JTK2" RELATED Gene-based []
synonym: "CD334" EXACT []
synonym: "FGFR4" EXACT PRO-short-label [PRO:DNx]
synonym: "FGFR-4" EXACT []
synonym: "Mpk-11" RELATED Gene-based []
synonym: "protein-tyrosine kinase receptor MPK-11" EXACT []
xref: IUPHARobj:1811
is_a: PR:000001349 ! fibroblast growth factor receptor

[Term]
id: PR:P22455
name: fibroblast growth factor receptor 4 (human)
def: "A fibroblast growth factor receptor 4 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-gene.
synonym: "TKF" RELATED Gene-based [UniProtKB:P22455]
synonym: "JTK2" RELATED Gene-based [UniProtKB:P22455]
synonym: "FGFR4" RELATED Gene-based [UniProtKB:P22455]
synonym: "hFGFR4" EXACT PRO-short-label [PRO:DNx]
synonym: "CD334 (human)" EXACT [UniProtKB:P22455]
synonym: "FGFR-4 (human)" EXACT [UniProtKB:P22455]
xref: DTO:03100152
xref: UniProtKB:P22455
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001451 ! fibroblast growth factor receptor 4
relationship: has_gene_template HGNC:3691 ! FGFR4 (human)

[Term]
id: PR:000047414
name: fibroblast growth factor receptor 4, signal peptide removed form (human)
def: "A fibroblast growth factor receptor 4 (human) that has had the signal peptide removed. UniProtKB:P22455, 22-802." [PRO:DNx, Reactome:R-HSA-189921]
comment: Category=organism-modification.
synonym: "PRO_0000016787" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hFGFR4/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P22455, 22-802" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-189921 "PR:000047414 located_in GO:0005886"
intersection_of: PR:P22455 ! fibroblast growth factor receptor 4 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047415
name: fibroblast growth factor receptor 4, signal peptide removed phosphorylated 1 (human)
def: "A fibroblast growth factor receptor 4 (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 642, 643, 719, 754 and 764 of the amino acid sequence represented by UniProtKB:P22455. UniProtKB:P22455, 22-802, Tyr-642/Tyr-643/Tyr-719/Tyr-754/Tyr-764, MOD:00048." [PRO:DNx, Reactome:R-HSA-190330]
comment: Category=organism-modification.
synonym: "hFGFR4/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000016787, Tyr-642/Tyr-643/Tyr-719/Tyr-754/Tyr-764, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P22455, 22-802, Tyr-642/Tyr-643/Tyr-719/Tyr-754/Tyr-764, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-190330 "PR:000047415 located_in GO:0005886"
is_a: PR:P22455 ! fibroblast growth factor receptor 4 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide