[Term] id: PR:P22301-1 name: interleukin-10 isoform 1 (human) def: "An interleukin-10 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hIL10/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P22301-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039066 ! interleukin-10 isoform 1 [Term] id: PR:P22301 name: interleukin-10 (human) def: "An interleukin-10 that is encoded in the genome of human." [PRO:JAN, UniProtKB:P22301] comment: Category=organism-gene. synonym: "IL10" RELATED Gene-based [UniProtKB:P22301] synonym: "hIL10" EXACT PRO-short-label [PRO:DNx] synonym: "CSIF (human)" EXACT [UniProtKB:P22301] synonym: "IL-10 (human)" EXACT [UniProtKB:P22301] synonym: "cytokine synthesis inhibitory factor (human)" EXACT [UniProtKB:P22301] xref: UniProtKB:P22301 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001471 ! interleukin-10 relationship: has_gene_template HGNC:5962 ! IL10 (human) [Term] id: PR:000001471 name: interleukin-10 def: "A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds." [PANTHER:PTHR11585:SF1, PRO:JAN] comment: Category=gene. synonym: "CSIF" EXACT [] synonym: "IL10" EXACT PRO-short-label [PRO:DNx] synonym: "IL-10" EXACT [] synonym: "cytokine synthesis inhibitory factor" EXACT [] is_a: PR:000001335 ! class 2 cytokine, IL-10 type