[Term] id: PR:000001592 name: leucine-rich repeat-containing G-protein coupled receptor 5 def: "A leucine-rich repeat-containing G-protein coupled receptor 4/5/6 that is a translation product of the human LGR5 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "Fex" RELATED Gene-based [] synonym: "LGR5" EXACT PRO-short-label [PRO:DNx] synonym: "GPR49" RELATED Gene-based [] synonym: "GPR67" RELATED Gene-based [] synonym: "G-protein coupled receptor 49" EXACT [] synonym: "G-protein coupled receptor 67" EXACT [] synonym: "G-protein coupled receptor HG38" EXACT [] synonym: "orphan G-protein coupled receptor FEX" EXACT [] xref: IUPHARobj:148 is_a: PR:000001477 ! leucine-rich repeat-containing G-protein coupled receptor 4/5/6 [Term] id: PR:O75473 name: leucine-rich repeat-containing G-protein coupled receptor 5 (human) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O75473] comment: Category=organism-gene. synonym: "LGR5" RELATED Gene-based [UniProtKB:O75473] synonym: "GPR49" RELATED Gene-based [UniProtKB:O75473] synonym: "GPR67" RELATED Gene-based [UniProtKB:O75473] synonym: "hLGR5" EXACT PRO-short-label [PRO:DNx] synonym: "G-protein coupled receptor 49 (human)" EXACT [UniProtKB:O75473] synonym: "G-protein coupled receptor 67 (human)" EXACT [UniProtKB:O75473] synonym: "G-protein coupled receptor HG38 (human)" EXACT [UniProtKB:O75473] xref: DTO:02100236 xref: UniProtKB:O75473 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001592 ! leucine-rich repeat-containing G-protein coupled receptor 5 relationship: has_gene_template HGNC:4504 ! LGR5 (human) [Term] id: PR:Q9Z1P4 name: leucine-rich repeat-containing G-protein coupled receptor 5 (mouse) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 that is encoded in the genome of mouse." [OMA:Q9Z1P4, PRO:DNx] comment: Category=organism-gene. synonym: "Fex" RELATED Gene-based [UniProtKB:Q9Z1P4] synonym: "Lgr5" RELATED Gene-based [UniProtKB:Q9Z1P4] synonym: "Gpr49" RELATED Gene-based [UniProtKB:Q9Z1P4] synonym: "mLGR5" EXACT PRO-short-label [PRO:DNx] synonym: "G-protein coupled receptor 49 (mouse)" EXACT [UniProtKB:Q9Z1P4] synonym: "orphan G-protein coupled receptor FEX (mouse)" EXACT [UniProtKB:Q9Z1P4] xref: UniProtKB:Q9Z1P4 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000001592 ! leucine-rich repeat-containing G-protein coupled receptor 5 relationship: has_gene_template MGI:1341817 ! Lgr5 (mouse) [Term] id: PR:D4AC13 name: leucine-rich repeat-containing G-protein coupled receptor 5 (rat) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 that is encoded in the genome of rat." [OMA:D4AC13, PRO:DNx] comment: Category=organism-gene. synonym: "Lgr5" RELATED Gene-based [UniProtKB:D4AC13] synonym: "rLGR5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:D4AC13 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000001592 ! leucine-rich repeat-containing G-protein coupled receptor 5 relationship: has_gene_template RGD:1307733 ! Lgr5 (rat) [Term] id: PR:000048194 name: leucine-rich repeat-containing G-protein coupled receptor 5, signal peptide removed form (human) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 (human) that has had the signal peptide removed. UniProtKB:O75473, 22-907." [PRO:DNx, Reactome:R-HSA-4641171] comment: Category=organism-modification. synonym: "hLGR5/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000012794" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:O75473, 22-907" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4641171 "PR:000048194 located_in GO:0005886" intersection_of: PR:O75473 ! leucine-rich repeat-containing G-protein coupled receptor 5 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000038361 name: leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 def: "A leucine-rich repeat-containing G-protein coupled receptor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75473-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "LGR5/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000001592 ! leucine-rich repeat-containing G-protein coupled receptor 5 [Term] id: PR:O75473-2 name: leucine-rich repeat-containing G-protein coupled receptor 5 isoform h2 (human) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75473-2." [PRO:DNx, UniProtKB:O75473] comment: Category=organism-sequence. synonym: "hLGR5/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O75473-2 is_a: PR:O75473 ! leucine-rich repeat-containing G-protein coupled receptor 5 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O75473-3 name: leucine-rich repeat-containing G-protein coupled receptor 5 isoform h3 (human) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75473-3." [PRO:DNx, UniProtKB:O75473] comment: Category=organism-sequence. synonym: "hLGR5/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O75473-3 is_a: PR:O75473 ! leucine-rich repeat-containing G-protein coupled receptor 5 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:D4AC13-1 name: leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 (rat) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rLGR5/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:D4AC13-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000038361 ! leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 [Term] id: PR:O75473-1 name: leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 (human) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hLGR5/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O75473-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038361 ! leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 [Term] id: PR:Q9Z1P4-1 name: leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 (mouse) def: "A leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mLGR5/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z1P4-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000038361 ! leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1