[Term] id: PR:000001659 name: prostaglandin E2 receptor EP3 subtype def: "A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney." [PMID:7938166, PRO:WCB] comment: Category=gene. synonym: "PGE2-R" EXACT [] synonym: "PTGER3" EXACT PRO-short-label [PRO:DNx] synonym: "Ptgerep3" RELATED Gene-based [] synonym: "prostanoid EP3 receptor" EXACT [] synonym: "PGE receptor EP3 subtype" EXACT [] synonym: "PGE2 receptor EP3 subtype" EXACT [] synonym: "prostaglandin E2 receptor EP3" EXACT [] xref: IUPHARobj:342 is_a: PR:000001549 ! prostanoid receptor