[Term]
id: PR:P25116
name: proteinase-activated receptor 1 (human)
def: "A proteinase-activated receptor 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P25116]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "TR" RELATED Gene-based [UniProtKB:P25116]
synonym: "F2R" RELATED Gene-based [UniProtKB:P25116]
synonym: "CF2R" RELATED Gene-based [UniProtKB:P25116]
synonym: "PAR1" RELATED Gene-based [UniProtKB:P25116]
synonym: "hF2R" EXACT PRO-short-label [PRO:DNx]
synonym: "PAR-1 (human)" EXACT [UniProtKB:P25116]
synonym: "thrombin receptor (human)" EXACT [UniProtKB:P25116]
synonym: "coagulation factor II receptor (human)" EXACT [UniProtKB:P25116]
xref: DTO:02100737
xref: UniProtKB:P25116
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001661 ! proteinase-activated receptor 1
relationship: has_gene_template HGNC:3537 ! F2R (human)

[Term]
id: PR:P30558
name: proteinase-activated receptor 1 (mouse)
def: "A proteinase-activated receptor 1 that is encoded in the genome of mouse." [OMA:P30558, PRO:DNx]
comment: Category=organism-gene.
synonym: "F2r" RELATED Gene-based [UniProtKB:P30558]
synonym: "Cf2r" RELATED Gene-based [UniProtKB:P30558]
synonym: "Par1" RELATED Gene-based [UniProtKB:P30558]
synonym: "mF2R" EXACT PRO-short-label [PRO:DNx]
synonym: "PAR-1 (mouse)" EXACT [UniProtKB:P30558]
synonym: "thrombin receptor (mouse)" EXACT [UniProtKB:P30558]
xref: UniProtKB:P30558
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001661 ! proteinase-activated receptor 1
relationship: has_gene_template MGI:101802 ! F2r (mouse)

[Term]
id: PR:000001661
name: proteinase-activated receptor 1
def: "A proteinase-activated receptor that is a translation product of the human F2R gene or a 1:1 ortholog thereof. It is activated by thrombin, which cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity." [PMID:1672265, PRO:WCB]
comment: Category=gene.
synonym: "TR" RELATED Gene-based []
synonym: "F2R" EXACT PRO-short-label [PRO:DNx]
synonym: "CF2R" RELATED Gene-based []
synonym: "PAR1" RELATED Gene-based []
synonym: "PAR-1" EXACT []
synonym: "thrombin receptor" EXACT []
synonym: "coagulation factor II receptor" EXACT []
xref: IUPHARobj:347
is_a: PR:000001550 ! proteinase-activated receptor

[Term]
id: PR:000018513
name: proteinase-activated receptor 1 proteolytic cleavage product
def: "A proteinase-activated receptor 1 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "F2R/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000001661 ! proteinase-activated receptor 1

[Term]
id: PR:P26824
name: proteinase-activated receptor 1 (rat)
def: "A proteinase-activated receptor 1 that is encoded in the genome of rat." [PANTHER:PTHR24232:SF221, PRO:DNx]
comment: Category=organism-gene.
synonym: "F2r" RELATED Gene-based [UniProtKB:P26824]
synonym: "Par1" RELATED Gene-based [UniProtKB:P26824]
synonym: "rF2R" EXACT PRO-short-label [PRO:DNx]
synonym: "PAR-1 (rat)" EXACT [UniProtKB:P26824]
synonym: "thrombin receptor (rat)" EXACT [UniProtKB:P26824]
xref: UniProtKB:P26824
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000001661 ! proteinase-activated receptor 1
relationship: has_gene_template RGD:2586 ! F2r (rat)