[Term]
id: PR:000035831
name: inhibitor of nuclear factor kappa-B kinase subunit beta phosphorylated 1 (human)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta phosphorylated 1 in human. UniProtKB:O14920, Ser-177/Ser-181, MOD:00046." [PRO:DNx, UniProtKB:O14920]
comment: Category=organism-modification. Kinase=("p-T184,187-TAK1"; PR:000035736).
synonym: "hIKBKB/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "phospho-IKK2 (human)" EXACT [Reactome:R-HSA-202506]
synonym: "p-S177,S181-IKK beta (human)" EXACT [Reactome:R-HSA-202506]
synonym: "UniProtKB:O14920, Ser-177/Ser-181, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-202506 "PR:000035831 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035830 ! inhibitor of nuclear factor kappa-B kinase subunit beta phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:O14920
name: inhibitor of nuclear factor kappa-B kinase subunit beta (human)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14920]
comment: Category=organism-gene.
synonym: "IKKB" RELATED Gene-based [UniProtKB:O14920]
synonym: "IKBKB" RELATED Gene-based [UniProtKB:O14920]
synonym: "hIKBKB" EXACT PRO-short-label [PRO:DNx]
synonym: "IKK2 (human)" EXACT [UniProtKB:O14920]
synonym: "IKK-B (human)" EXACT [UniProtKB:O14920]
synonym: "IkBKB (human)" EXACT [UniProtKB:O14920]
synonym: "NFKBIKB (human)" EXACT [UniProtKB:O14920]
synonym: "IKK-beta (human)" EXACT [UniProtKB:O14920]
synonym: "I-kappa-B kinase 2 (human)" EXACT [UniProtKB:O14920]
synonym: "I-kappa-B-kinase beta (human)" EXACT [UniProtKB:O14920]
synonym: "serine/threonine protein kinase IKBKB (human)" EXACT [UniProtKB:O14920]
synonym: "nuclear factor NF-kappa-B inhibitor kinase beta (human)" EXACT [UniProtKB:O14920]
xref: Reactome:R-HSA-168114 "PR:O14920 located_in GO:0005829"
xref: Reactome:R-HSA-1168584 "PR:O14920 located_in GO:0005886"
xref: DTO:03100182
xref: UniProtKB:O14920
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001776 ! inhibitor of nuclear factor kappa-B kinase subunit beta
relationship: has_gene_template HGNC:5960 ! IKBKB (human)

[Term]
id: PR:O14920-3
name: inhibitor of nuclear factor kappa-B kinase subunit beta isoform h3 (human)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14920-3." [PRO:DNx, UniProtKB:O14920]
comment: Category=organism-sequence.
synonym: "hIKBKB/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14920-3
is_a: PR:O14920 ! inhibitor of nuclear factor kappa-B kinase subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14920-2
name: inhibitor of nuclear factor kappa-B kinase subunit beta isoform h2 (human)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14920-2." [PRO:DNx, UniProtKB:O14920]
comment: Category=organism-sequence.
synonym: "hIKBKB/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14920-2
is_a: PR:O14920 ! inhibitor of nuclear factor kappa-B kinase subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14920-1
name: inhibitor of nuclear factor kappa-B kinase subunit beta isoform h1 (human)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14920-1." [PRO:DNx, UniProtKB:O14920]
comment: Category=organism-sequence.
synonym: "hIKBKB/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14920-1
is_a: PR:O14920 ! inhibitor of nuclear factor kappa-B kinase subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14920-4
name: inhibitor of nuclear factor kappa-B kinase subunit beta isoform h4 (human)
def: "An inhibitor of nuclear factor kappa-B kinase subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14920-4." [PRO:DNx, UniProtKB:O14920]
comment: Category=organism-sequence.
synonym: "hIKBKB/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14920-4
is_a: PR:O14920 ! inhibitor of nuclear factor kappa-B kinase subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001776
name: inhibitor of nuclear factor kappa-B kinase subunit beta
def: "An inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits that is a translation product of the human IKBKB gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "IKK2" EXACT []
synonym: "IKKB" RELATED Gene-based []
synonym: "IKBKB" EXACT PRO-short-label [PRO:DNx]
synonym: "IKK-B" EXACT []
synonym: "IkBKB" EXACT []
synonym: "NFKBIKB" EXACT []
synonym: "IKK-beta" EXACT []
synonym: "I-kappa-B kinase 2" EXACT []
synonym: "I-kappa-B-kinase beta" EXACT []
synonym: "serine/threonine protein kinase IKBKB" EXACT []
synonym: "nuclear factor NF-kappa-B inhibitor kinase beta" EXACT []
xref: IUPHARobj:2039
is_a: PR:000001774 ! inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits