[Term]
id: PR:000001780
name: interleukin-1 receptor-associated kinase 4
def: "A protein that is a translation product of the human IRAK4 gene or a 1:1 ortholog thereof. The archetypical form consists of an N-terminal Death domain (Pfam:PF00531) and a C-terminal Protein kinase domain (Pfam:PF00069). This protein is an essential component of innate immunity." [PMID:11960013, PMID:16177054, PRO:CNA]
comment: Category=gene.
synonym: "IRAK4" EXACT PRO-short-label [PRO:DNx]
synonym: "IRAK-4" EXACT []
synonym: "renal carcinoma antigen NY-REN-64" EXACT []
xref: IUPHARobj:2045
xref: PIRSF:PIRSF038189
is_a: PR:000000001 ! protein