[Term]
id: PR:000001809
name: CD59-like glycoprotein
def: "A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL. Pro-orthology refers to, in this case, after-speciation gene duplication in the non-human species (aka 1:many orthology). This gene is present as a single copy in human and has undergone a lineage-specific duplication in mouse. CD59 antigen has a core architecture consisting of one UPAR/Ly-6 domain (Pfam:PF00021), a small domain of about 70 amino acids and containing 5 conserved disulfide bonds. It is both N- and O-glycosylated and is a GPI-anchored protein that releases soluble forms in some tissues.
synonym: "CD59-like" EXACT PRO-short-label [PRO:DNx]
xref: PIRSF:PIRSF038782
is_a: PR:000000001 ! protein