[Term]
id: PR:Q63994-2
name: myeloid cell surface antigen CD33 isoform m33-A (mouse)
def: "A myeloid cell surface antigen CD33 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63994-2." [PRO:DNx, UniProtKB:Q63994]
comment: Category=organism-sequence.
synonym: "mCD33/iso:m33-A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q63994-2
is_a: PR:Q63994 ! myeloid cell surface antigen CD33 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000001892
name: CD33 molecule
def: "A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD33" EXACT PRO-short-label [PRO:DNx]
synonym: "gp67" EXACT []
synonym: "SIGLEC3" RELATED Gene-based []
synonym: "siglec-3" EXACT []
synonym: "myeloid cell surface antigen CD33" EXACT []
synonym: "sialic acid-binding Ig-like lectin 3" EXACT []
xref: IUPHARobj:2601
is_a: PR:000000001 ! protein

[Term]
id: PR:Q63994
name: myeloid cell surface antigen CD33 (mouse)
def: "A CD33 molecule that is encoded in the genome of mouse." [PRO:WCB]
comment: Category=organism-gene.
synonym: "Cd33" RELATED Gene-based [UniProtKB:Q63994]
synonym: "mCD33" EXACT PRO-short-label [PRO:DNx]
synonym: "Siglec3" RELATED Gene-based [UniProtKB:Q63994]
synonym: "CD33 (mouse)" EXACT [UniProtKB:Q63994]
synonym: "siglec-3 (mouse)" EXACT [UniProtKB:Q63994]
synonym: "sialic acid-binding Ig-like lectin 3 (mouse)" EXACT [UniProtKB:Q63994]
xref: UniProtKB:Q63994
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001892 ! CD33 molecule
relationship: has_gene_template MGI:99440 ! Cd33 (mouse)

[Term]
id: PR:Q63994-1
name: myeloid cell surface antigen CD33 isoform m33-B (mouse)
def: "A myeloid cell surface antigen CD33 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63994-1." [PRO:DNx, UniProtKB:Q63994]
comment: Category=organism-sequence.
synonym: "mCD33/iso:m33-B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q63994-1
is_a: PR:Q63994 ! myeloid cell surface antigen CD33 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P20138
name: myeloid cell surface antigen CD33 (human)
def: "A CD33 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P20138]
comment: Category=organism-gene.
synonym: "CD33" RELATED Gene-based [UniProtKB:P20138]
synonym: "hCD33" EXACT PRO-short-label [PRO:DNx]
synonym: "SIGLEC3" RELATED Gene-based [UniProtKB:P20138]
synonym: "gp67 (human)" EXACT [UniProtKB:P20138]
synonym: "siglec-3 (human)" EXACT [UniProtKB:P20138]
synonym: "sialic acid-binding Ig-like lectin 3 (human)" EXACT [UniProtKB:P20138]
xref: UniProtKB:P20138
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001892 ! CD33 molecule
relationship: has_gene_template HGNC:1659 ! CD33 (human)

[Term]
id: PR:000056102
name: myeloid cell surface antigen CD33 O-glycosylated 2 (human)
def: "A myeloid cell surface antigen CD33 (human) that has been O-glycosylated at the residue equivalent to Thr-240 of the amino acid sequence represented by UniProtKB:P20138-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P20138-1, Thr-240, MOD:00005~GNO:G43417UB." [GlyGen:P20138-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD33/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P20138-1, Thr-240, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P20138 ! myeloid cell surface antigen CD33 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056101
name: myeloid cell surface antigen CD33 O-glycosylated 1 (human)
def: "A myeloid cell surface antigen CD33 (human) that has been O-glycosylated at the residue equivalent to Thr-239 of the amino acid sequence represented by UniProtKB:P20138-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P20138-1, Thr-239, MOD:00005~GNO:G43417UB." [GlyGen:P20138-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD33/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P20138-1, Thr-239, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P20138 ! myeloid cell surface antigen CD33 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046634
name: myeloid cell surface antigen CD33, signal peptide removed form (human)
def: "A myeloid cell surface antigen CD33 (human) that has had the signal peptide removed. UniProtKB:P20138, 18-364." [PRO:DNx, Reactome:R-HSA-197719]
comment: Category=organism-modification.
synonym: "hCD33/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014878" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P20138, 18-364" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-197719 "PR:000046634 located_in GO:0005886"
xref: Reactome:R-HSA-6799615 "PR:000046634 located_in GO:0035579"
xref: Reactome:R-HSA-6800959 "PR:000046634 located_in GO:0070821"
intersection_of: PR:P20138 ! myeloid cell surface antigen CD33 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20138-2
name: myeloid cell surface antigen CD33 isoform h3 (human)
def: "A myeloid cell surface antigen CD33 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20138-2." [PRO:DNx, UniProtKB:P20138]
comment: Category=organism-sequence.
synonym: "hCD33/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20138-2
is_a: PR:P20138 ! myeloid cell surface antigen CD33 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20138-3
name: myeloid cell surface antigen CD33 isoform hCD33m (human)
def: "A myeloid cell surface antigen CD33 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20138-3." [PRO:DNx, UniProtKB:P20138]
comment: Category=organism-sequence.
synonym: "hCD33/iso:hCD33m" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20138-3
is_a: PR:P20138 ! myeloid cell surface antigen CD33 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20138-1
name: myeloid cell surface antigen CD33 isoform hCD33M (human)
def: "A myeloid cell surface antigen CD33 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20138-1." [PRO:DNx, UniProtKB:P20138]
comment: Category=organism-sequence.
synonym: "hCD33/iso:hCD33M" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20138-1
is_a: PR:P20138 ! myeloid cell surface antigen CD33 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens