[Term]
id: PR:P40238
name: thrombopoietin receptor (human)
def: "A thrombopoietin receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P40238]
comment: Category=organism-gene.
synonym: "MPL" RELATED Gene-based [UniProtKB:P40238]
synonym: "TPOR" RELATED Gene-based [UniProtKB:P40238]
synonym: "hMPL" EXACT PRO-short-label [PRO:DNx]
synonym: "CD110 (human)" EXACT [UniProtKB:P40238]
synonym: "TPO-R (human)" EXACT [UniProtKB:P40238]
synonym: "proto-oncogene c-Mpl (human)" EXACT [UniProtKB:P40238]
synonym: "myeloproliferative leukemia protein (human)" EXACT [UniProtKB:P40238]
xref: UniProtKB:P40238
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001939 ! thrombopoietin receptor
relationship: has_gene_template HGNC:7217 ! MPL (human)

[Term]
id: PR:Q08351-2
name: thrombopoietin receptor isoform Mpl-tr (mouse)
def: "A thrombopoietin receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08351-2." [PRO:DNx, UniProtKB:Q08351]
comment: Category=organism-sequence.
synonym: "mMPL/iso:Mpl-tr" EXACT PRO-short-label [PRO:DNx]
synonym: "thrombopoietin receptor isoform Mpl-truncated (mouse)" EXACT [UniProtKB:Q08351]
xref: UniProtKB:Q08351-2
is_a: PR:Q08351 ! thrombopoietin receptor (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q08351-1
name: thrombopoietin receptor isoform Mpl-fl (mouse)
def: "A thrombopoietin receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08351-1." [PRO:DNx, UniProtKB:Q08351]
comment: Category=organism-sequence.
synonym: "mMPL/iso:Mpl-fl" EXACT PRO-short-label [PRO:DNx]
synonym: "thrombopoietin receptor isoform Mpl-full-length (mouse)" EXACT [UniProtKB:Q08351]
xref: UniProtKB:Q08351-1
is_a: PR:Q08351 ! thrombopoietin receptor (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000048414
name: thrombopoietin receptor, signal peptide removed form (human)
def: "A thrombopoietin receptor (human) that has had the signal peptide removed. UniProtKB:P40238, 26-635." [PRO:DNx, Reactome:R-HSA-443938]
comment: Category=organism-modification.
synonym: "hMPL/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010987" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P40238, 26-635" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-443938 "PR:000048414 located_in GO:0005886"
intersection_of: PR:P40238 ! thrombopoietin receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40238-2
name: thrombopoietin receptor isoform h2 (human)
def: "A thrombopoietin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40238-2." [PRO:DNx, UniProtKB:P40238]
comment: Category=organism-sequence.
synonym: "hMPL/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "thrombopoietin receptor isoform C-mpl-K (human)" EXACT [UniProtKB:P40238]
xref: UniProtKB:P40238-2
is_a: PR:P40238 ! thrombopoietin receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40238-1
name: thrombopoietin receptor isoform h1 (human)
def: "A thrombopoietin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40238-1." [PRO:DNx, UniProtKB:P40238]
comment: Category=organism-sequence.
synonym: "hMPL/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "thrombopoietin receptor isoform C-mpl-P (human)" EXACT [UniProtKB:P40238]
xref: UniProtKB:P40238-1
is_a: PR:P40238 ! thrombopoietin receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q08351
name: thrombopoietin receptor (mouse)
def: "A thrombopoietin receptor that is encoded in the genome of mouse." [OMA:Q08351, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mpl" RELATED Gene-based [UniProtKB:Q08351]
synonym: "Tpor" RELATED Gene-based [UniProtKB:Q08351]
synonym: "mMPL" EXACT PRO-short-label [PRO:DNx]
synonym: "CD110 (mouse)" EXACT [UniProtKB:Q08351]
synonym: "TPO-R (mouse)" EXACT [UniProtKB:Q08351]
synonym: "proto-oncogene c-Mpl (mouse)" EXACT [UniProtKB:Q08351]
synonym: "myeloproliferative leukemia protein (mouse)" EXACT [UniProtKB:Q08351]
xref: UniProtKB:Q08351
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001939 ! thrombopoietin receptor
relationship: has_gene_template MGI:97076 ! Mpl (mouse)

[Term]
id: PR:000001939
name: thrombopoietin receptor
def: "A protein that is a translation product of the human MPL gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "MPL" EXACT PRO-short-label [PRO:DNx]
synonym: "TPOR" RELATED Gene-based []
synonym: "CD110" EXACT []
synonym: "TPO-R" EXACT []
synonym: "proto-oncogene c-Mpl" EXACT []
synonym: "myeloproliferative leukemia protein" EXACT []
xref: IUPHARobj:1722
is_a: PR:000000001 ! protein