[Term]
id: PR:000002062
name: macrophage colony-stimulating factor 1 receptor
def: "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "FMS" RELATED Gene-based []
synonym: "CD115" EXACT []
synonym: "CSF1R" EXACT PRO-short-label [PRO:DNx]
synonym: "Csfmr" RELATED Gene-based []
synonym: "CSF-1R" EXACT []
synonym: "CSF-1-R" EXACT []
synonym: "M-CSF-R" EXACT []
synonym: "CSF-1 receptor" EXACT []
synonym: "proto-oncogene c-Fms" EXACT []
xref: IUPHARobj:1806
xref: PIRSF:PIRSF500947
is_a: PR:000001810 ! CSF-1/PDGF receptor-type tyrosine-protein kinase

[Term]
id: PR:000046135
name: macrophage colony-stimulating factor 1 receptor phosphorylated 1 (mouse)
def: "A macrophage colony-stimulating factor 1 receptor (mouse) that has been phosphorylated at Tyr-921. UniProtKB:P09581, Tyr-921, MOD:00048." [PMID:9380408, iPTMnet:P09581]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:9380408). Status=unreviewed.
synonym: "mCSF1R/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P09581, Tyr-921, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P09581 ! macrophage colony-stimulating factor 1 receptor (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P07333
name: macrophage colony-stimulating factor 1 receptor (human)
def: "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P07333]
comment: Category=organism-gene.
synonym: "FMS" RELATED Gene-based [UniProtKB:P07333]
synonym: "CSF1R" RELATED Gene-based [UniProtKB:P07333]
synonym: "hCSF1R" EXACT PRO-short-label [PRO:DNx]
synonym: "CD115 (human)" EXACT [UniProtKB:P07333]
synonym: "CSF-1R (human)" EXACT [UniProtKB:P07333]
synonym: "CSF-1-R (human)" EXACT [UniProtKB:P07333]
synonym: "M-CSF-R (human)" EXACT [UniProtKB:P07333]
synonym: "CSF-1 receptor (human)" EXACT [UniProtKB:P07333]
synonym: "proto-oncogene c-Fms (human)" EXACT [UniProtKB:P07333]
xref: DTO:03100090
xref: UniProtKB:P07333
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002062 ! macrophage colony-stimulating factor 1 receptor
relationship: has_gene_template HGNC:2433 ! CSF1R (human)

[Term]
id: PR:000047079
name: macrophage colony-stimulating factor 1 receptor, signal peptide removed form (human)
def: "A macrophage colony-stimulating factor 1 receptor (human) that has had the signal peptide removed. UniProtKB:P07333, 20-972." [PRO:DNx, Reactome:R-HSA-197667]
comment: Category=organism-modification.
synonym: "PRO_0000016765" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCSF1R/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07333, 20-972" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-197667 "PR:000047079 located_in GO:0005886"
intersection_of: PR:P07333 ! macrophage colony-stimulating factor 1 receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P09581
name: macrophage colony-stimulating factor 1 receptor (mouse)
def: "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse." [OMA:P09581, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fms" RELATED Gene-based [UniProtKB:P09581]
synonym: "Csf1r" RELATED Gene-based [UniProtKB:P09581]
synonym: "Csfmr" RELATED Gene-based [UniProtKB:P09581]
synonym: "mCSF1R" EXACT PRO-short-label [PRO:DNx]
synonym: "CD115 (mouse)" EXACT [UniProtKB:P09581]
synonym: "CSF-1R (mouse)" EXACT [UniProtKB:P09581]
synonym: "CSF-1-R (mouse)" EXACT [UniProtKB:P09581]
synonym: "M-CSF-R (mouse)" EXACT [UniProtKB:P09581]
synonym: "CSF-1 receptor (mouse)" EXACT [UniProtKB:P09581]
synonym: "proto-oncogene c-Fms (mouse)" EXACT [UniProtKB:P09581]
xref: UniProtKB:P09581
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002062 ! macrophage colony-stimulating factor 1 receptor
relationship: has_gene_template MGI:1339758 ! Csf1r (mouse)

[Term]
id: PR:P07333-1
name: macrophage colony-stimulating factor 1 receptor isoform h1 (human)
def: "A macrophage colony-stimulating factor 1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07333-1." [PRO:DNx, UniProtKB:P07333]
comment: Category=organism-sequence.
synonym: "hCSF1R/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07333-1
is_a: PR:P07333 ! macrophage colony-stimulating factor 1 receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07333-2
name: macrophage colony-stimulating factor 1 receptor isoform h2 (human)
def: "A macrophage colony-stimulating factor 1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07333-2." [PRO:DNx, UniProtKB:P07333]
comment: Category=organism-sequence.
synonym: "hCSF1R/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07333-2
is_a: PR:P07333 ! macrophage colony-stimulating factor 1 receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q00495
name: macrophage colony-stimulating factor 1 receptor (rat)
def: "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of rat." [OMA:Q00495, PANTHER:PTHR24416:SF237, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fms" RELATED Gene-based [UniProtKB:Q00495]
synonym: "Csf1r" RELATED Gene-based [UniProtKB:Q00495]
synonym: "Csfmr" RELATED Gene-based [UniProtKB:Q00495]
synonym: "rCSF1R" EXACT PRO-short-label [PRO:DNx]
synonym: "CD115 (rat)" EXACT [UniProtKB:Q00495]
synonym: "CSF-1R (rat)" EXACT [UniProtKB:Q00495]
synonym: "CSF-1-R (rat)" EXACT [UniProtKB:Q00495]
synonym: "M-CSF-R (rat)" EXACT [UniProtKB:Q00495]
synonym: "CSF-1 receptor (rat)" EXACT [UniProtKB:Q00495]
synonym: "proto-oncogene c-Fms (rat)" EXACT [UniProtKB:Q00495]
xref: UniProtKB:Q00495
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000002062 ! macrophage colony-stimulating factor 1 receptor
relationship: has_gene_template RGD:2425 ! Csf1r (rat)