[Term] id: PR:000056374 name: neural cell adhesion molecule L1 N-glycosylated 2 (human) def: "A neural cell adhesion molecule L1 (human) that has been N-glycosylated at the residue equivalent to Asn-979 of the amino acid sequence represented by UniProtKB:P32004-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P32004-1, Asn-979, MOD:00160~GNO:G59626AS." [GlyGen:P32004-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hL1CAM/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P32004-1, Asn-979, MOD:00160~GNO:G59626AS" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P32004 ! neural cell adhesion molecule L1 (human) relationship: has_part GNO:G59626AS ! G59626AS relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000002066 name: neural cell adhesion molecule L1 def: "A neural cell adhesion molecule-like protein that is a translation product of the human L1CAM gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "MIC5" RELATED Gene-based [] synonym: "CAML1" RELATED Gene-based [] synonym: "CD171" EXACT [] synonym: "L1CAM" EXACT PRO-short-label [PRO:DNx] synonym: "NCAM-L1" EXACT [] synonym: "N-CAM-L1" EXACT [] is_a: PR:000001899 ! neural cell adhesion molecule-like protein [Term] id: PR:000048145 name: neural cell adhesion molecule L1, signal peptide removed phosphorylated 2 (human) def: "A neural cell adhesion molecule L1, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Ser-1152 of the amino acid sequence represented by UniProtKB:P32004. UniProtKB:P32004, 20-1257, Ser-1152, MOD:00046." [PRO:DNx, Reactome:R-HSA-374599] comment: Category=organism-modification. synonym: "hL1CAM/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015022, Ser-1152, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32004, 20-1257, Ser-1152, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-374599 "PR:000048145 located_in GO:0005886" is_a: PR:000028421 ! neural cell adhesion molecule L1, signal peptide removed form (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026222 name: neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 (human) def: "A neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 in human. Tyr-1176 of the YRSLE motif is phosphorylated by SRC tyrosine kinase associated with lipid rafts in the P-domain of the growth cone. Phosphorylation of Y1176 prevents L1 binding to AP-2, an adaptor required for clathrin mediated internalization of L1. UniProtKB:P32004-1, 20-1257, Tyr-1176, MOD:00048." [PMID:12082080, PRO:CNA] comment: Category=organism-modification. synonym: "hL1CAM/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DAN] synonym: "PRO_0000015022, Tyr-1176, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32004-1, 20-1257, Tyr-1176, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-444985 "PR:000026222 located_in GO:0005886" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026192 ! neural cell adhesion molecule L1 isoform 1, signal peptide removed phosphorylated 1 relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine [Term] id: PR:000048147 name: neural cell adhesion molecule L1, signal peptide removed phosphorylated 4 (human) def: "A neural cell adhesion molecule L1, signal peptide removed form (human) that has been post-translationally modified to include phosphoserine at positions 1204 and 1248 of the amino acid sequence represented by UniProtKB:P32004. UniProtKB:P32004, 20-1257, Ser-1204/Ser-1248, MOD:00046." [PRO:DNx, Reactome:R-HSA-444982] comment: Category=organism-modification. synonym: "hL1CAM/SigPep-/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015022, Ser-1204/Ser-1248, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32004, 20-1257, Ser-1204/Ser-1248, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-444982 "PR:000048147 located_in GO:0005886" is_a: PR:000028421 ! neural cell adhesion molecule L1, signal peptide removed form (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048146 name: neural cell adhesion molecule L1, signal peptide removed phosphorylated 3 (human) def: "A neural cell adhesion molecule L1, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Ser-1181 of the amino acid sequence represented by UniProtKB:P32004. UniProtKB:P32004, 20-1257, Ser-1181, MOD:00046." [PRO:DNx, Reactome:R-HSA-392737] comment: Category=organism-modification. synonym: "hL1CAM/SigPep-/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015022, Ser-1181, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32004, 20-1257, Ser-1181, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-392737 "PR:000048146 located_in GO:0005886" is_a: PR:000028421 ! neural cell adhesion molecule L1, signal peptide removed form (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048149 name: neural cell adhesion molecule L1, signal peptide removed phosphotyrosine form (human) def: "A neural cell adhesion molecule L1, signal peptide removed form (human) that includes at least one phosphorylated tyrosine. UniProtKB:P32004, 20-1257, MOD:00048." [PRO:DNx, Reactome:R-HSA-443808] comment: Category=organism-modification. synonym: "hL1CAM/SigPep-/PhosTyr+" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015022, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32004, 20-1257, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-443808 "PR:000048149 located_in GO:0005886" intersection_of: has_part MOD:00048 ! O4'-phospho-L-tyrosine intersection_of: PR:000028421 ! neural cell adhesion molecule L1, signal peptide removed form (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048148 name: neural cell adhesion molecule L1, signal peptide removed phosphorylated 5 (human) def: "A neural cell adhesion molecule L1, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1229 of the amino acid sequence represented by UniProtKB:P32004. UniProtKB:P32004, 20-1257, Tyr-1229, MOD:00048." [PRO:DNx, Reactome:R-HSA-444980] comment: Category=organism-modification. synonym: "hL1CAM/SigPep-/Phos:5" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000015022, Tyr-1229, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P32004, 20-1257, Tyr-1229, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-444980 "PR:000048148 located_in GO:0005886" is_a: PR:000028421 ! neural cell adhesion molecule L1, signal peptide removed form (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P32004-1 name: neural cell adhesion molecule L1 isoform 1 (human) def: "A neural cell adhesion molecule L1 isoform 1 that is encoded in the genome of human." [PRO:CNx] comment: Category=organism-sequence. synonym: "hL1CAM/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P32004-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026190 ! neural cell adhesion molecule L1 isoform 1 [Term] id: PR:P32004 name: neural cell adhesion molecule L1 (human) def: "A neural cell adhesion molecule L1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P32004] comment: Category=organism-gene. synonym: "MIC5" RELATED Gene-based [UniProtKB:P32004] synonym: "CAML1" RELATED Gene-based [UniProtKB:P32004] synonym: "L1CAM" RELATED Gene-based [UniProtKB:P32004] synonym: "hL1CAM" EXACT PRO-short-label [PRO:DNx] synonym: "CD171 (human)" EXACT [UniProtKB:P32004] synonym: "NCAM-L1 (human)" EXACT [UniProtKB:P32004] synonym: "N-CAM-L1 (human)" EXACT [UniProtKB:P32004] xref: UniProtKB:P32004 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002066 ! neural cell adhesion molecule L1 relationship: has_gene_template HGNC:6470 ! L1CAM (human) [Term] id: PR:P32004-3 name: neural cell adhesion molecule L1 isoform h3 (human) def: "A neural cell adhesion molecule L1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32004-3." [PRO:DNx, UniProtKB:P32004] comment: Category=organism-sequence. synonym: "hL1CAM/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P32004-3 is_a: PR:P32004 ! neural cell adhesion molecule L1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P32004-2 name: neural cell adhesion molecule L1 isoform h2 (human) def: "A neural cell adhesion molecule L1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32004-2." [PRO:DNx, UniProtKB:P32004] comment: Category=organism-sequence. synonym: "hL1CAM/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P32004-2 is_a: PR:P32004 ! neural cell adhesion molecule L1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000028421 name: neural cell adhesion molecule L1, signal peptide removed form (human) def: "A neural cell adhesion molecule L1, signal peptide removed form in human. Example: UniProtKB:P32004-1, 20-1257." [PRO:DNx] comment: Category=organism-modification. synonym: "PRO_0000015022" NARROW PRO-proteoform-ftid [PRO:DNx] synonym: "hL1CAM/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P32004-1, 20-1257" NARROW PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-191465 "PR:000028421 located_in GO:0005886" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000018715 ! neural cell adhesion molecule L1, signal peptide removed form [Term] id: PR:000056373 name: neural cell adhesion molecule L1 N-glycosylated 1 (human) def: "A neural cell adhesion molecule L1 (human) that has been N-glycosylated at the residue equivalent to Asn-979 of the amino acid sequence represented by UniProtKB:P32004-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P32004-1, Asn-979, MOD:00160~GNO:G00912UN." [GlyGen:P32004-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hL1CAM/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P32004-1, Asn-979, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P32004 ! neural cell adhesion molecule L1 (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens