[Term] id: PR:Q08881-1 name: tyrosine-protein kinase ITK/TSK isoform 1 (human) def: "A tyrosine-protein kinase ITK/TSK isoform 2 that is encoded in the genome of human." [PRO:JAN] comment: Category=organism-sequence. synonym: "hITK/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q08881-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002239 ! tyrosine-protein kinase ITK/TSK isoform 2 [Term] id: PR:Q08881 name: tyrosine-protein kinase ITK/TSK (human) def: "A tyrosine-protein kinase ITK/TSK that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q08881] comment: Category=organism-gene. synonym: "EMT" RELATED Gene-based [UniProtKB:Q08881] synonym: "ITK" RELATED Gene-based [UniProtKB:Q08881] synonym: "LYK" RELATED Gene-based [UniProtKB:Q08881] synonym: "hITK" EXACT PRO-short-label [PRO:DNx] synonym: "kinase EMT (human)" EXACT [UniProtKB:Q08881] synonym: "T-cell-specific kinase (human)" EXACT [UniProtKB:Q08881] synonym: "tyrosine-protein kinase Lyk (human)" EXACT [UniProtKB:Q08881] synonym: "IL-2-inducible T-cell kinase (human)" EXACT [UniProtKB:Q08881] synonym: "interleukin-2-inducible T-cell kinase (human)" EXACT [UniProtKB:Q08881] xref: Reactome:R-HSA-202319 "PR:Q08881 located_in GO:0005829" xref: DTO:03100194 xref: UniProtKB:Q08881 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002111 ! tyrosine-protein kinase ITK/TSK relationship: has_gene_template HGNC:6171 ! ITK (human) [Term] id: PR:000048075 name: tyrosine-protein kinase ITK/TSK phosphorylated 2 (human) def: "A tyrosine-protein kinase ITK/TSK (human) that has been phosphorylated on the residue at the position equivalent to Tyr-512 of the amino acid sequence represented by UniProtKB:Q08881. UniProtKB:Q08881, Tyr-512, MOD:00048." [PMID:9312162, PRO:DNx, Reactome:R-HSA-422519] comment: Category=organism-modification. Requested by=ImmPort. synonym: "hITK/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "hITK (pTyr511)" EXACT [PRO:ADD, GOC:add] synonym: "UniProtKB:Q08881, Tyr-512, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-422519 "PR:000048075 located_in GO:0005829" is_a: PR:Q08881 ! tyrosine-protein kinase ITK/TSK (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000002111 name: tyrosine-protein kinase ITK/TSK def: "A TEC-type tyrosine-protein kinase that is a translation product of the human ITK gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "EMT" RELATED Gene-based [] synonym: "ITK" EXACT PRO-short-label [PRO:DNx] synonym: "LYK" RELATED Gene-based [] synonym: "Tlk" RELATED Gene-based [] synonym: "Tsk" RELATED Gene-based [] synonym: "kinase EMT" EXACT [] synonym: "kinase TLK" EXACT [] synonym: "T-cell-specific kinase" EXACT [] synonym: "tyrosine-protein kinase Lyk" EXACT [] synonym: "IL-2-inducible T-cell kinase" EXACT [] xref: IUPHARobj:2046 xref: PIRSF:PIRSF500766 is_a: PR:000001967 ! TEC-type tyrosine-protein kinase [Term] id: PR:000048074 name: tyrosine-protein kinase ITK/TSK phosphorylated 1 (human) def: "A tyrosine-protein kinase ITK/TSK (human) that has been post-translationally modified to include phosphotyrosine at positions 180 and 512 of the amino acid sequence represented by UniProtKB:Q08881. UniProtKB:Q08881, Tyr-180/Tyr-512, MOD:00048." [PRO:DNx, Reactome:R-HSA-2685616] comment: Category=organism-modification. synonym: "hITK/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q08881, Tyr-180/Tyr-512, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2685616 "PR:000048074 located_in GO:0005829" is_a: PR:Q08881 ! tyrosine-protein kinase ITK/TSK (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens