[Term]
id: PR:Q13158
name: FAS-associated death domain protein (human)
def: "A FAS-associated death domain protein that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "FADD" RELATED Gene-based [UniProtKB:Q13158]
synonym: "GIG3" RELATED Gene-based [UniProtKB:Q13158]
synonym: "MORT1" RELATED Gene-based [UniProtKB:Q13158]
synonym: "hFADD" EXACT PRO-short-label [PRO:DNx]
synonym: "growth-inhibiting gene 3 protein (human)" EXACT [UniProtKB:Q13158]
synonym: "mediator of receptor induced toxicity (human)" EXACT [UniProtKB:Q13158]
synonym: "FAS-associating death domain-containing protein (human)" EXACT [UniProtKB:Q13158]
xref: Reactome:R-HSA-54639 "PR:Q13158 located_in GO:0005829"
xref: UniProtKB:Q13158
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002189 ! FAS-associated death domain protein
relationship: has_gene_template HGNC:3573 ! FADD (human)

[Term]
id: PR:Q13158-1
name: FAS-associated death domain protein isoform 1 (human)
def: "A FAS-associated death domain protein isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hFADD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13158-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002285 ! FAS-associated death domain protein isoform 1

[Term]
id: PR:000045901
name: FAS-associated death domain protein phosphorylated 1 (human)
def: "A FAS-associated death domain protein (human) that has been phosphorylated at Ser-200. UniProtKB:Q13158, Ser-200, MOD:00046." [PMID:26253696, iPTMnet:Q13158]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26253696). Status=unreviewed.
synonym: "hFADD/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13158, Ser-200, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13158 ! FAS-associated death domain protein (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002189
name: FAS-associated death domain protein
def: "A protein that is a translation product of the human FADD gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "FADD" EXACT PRO-short-label [PRO:DNx]
synonym: "GIG3" RELATED Gene-based []
synonym: "MORT1" RELATED Gene-based []
synonym: "FADD protein" EXACT []
synonym: "protein FADD" EXACT []
synonym: "growth-inhibiting gene 3 protein" EXACT []
synonym: "mediator of receptor induced toxicity" EXACT []
synonym: "FAS-associating death domain-containing protein" EXACT []
xref: PIRSF:PIRSF018586
is_a: PR:000000001 ! protein