[Term]
id: PR:Q9EPV5
name: apoptotic protease-activating factor 1 (rat)
def: "An apoptotic protease-activating factor 1 that is encoded in the genome of rat." [OMA:Q9EPV5, PANTHER:PTHR22845:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Apaf1" RELATED Gene-based [UniProtKB:Q9EPV5]
synonym: "rAPAF1" EXACT PRO-short-label [PRO:DNx]
synonym: "APAF-1 (rat)" EXACT [UniProtKB:Q9EPV5]
xref: UniProtKB:Q9EPV5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000002194 ! apoptotic protease-activating factor 1
relationship: has_gene_template RGD:620575 ! Apaf1 (rat)

[Term]
id: PR:O14727
name: apoptotic protease-activating factor 1 (human)
def: "An apoptotic protease-activating factor 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O14727]
comment: Category=organism-gene.
synonym: "APAF1" RELATED Gene-based [UniProtKB:O14727]
synonym: "hAPAF1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0413" RELATED Gene-based [UniProtKB:O14727]
synonym: "APAF-1 (human)" EXACT [UniProtKB:O14727]
xref: Reactome:R-HSA-50099 "PR:O14727 located_in GO:0005829"
xref: Reactome:R-HSA-6806465 "PR:O14727 located_in GO:0005576"
xref: Reactome:R-HSA-6801271 "PR:O14727 located_in GO:0034774"
xref: Reactome:R-HSA-6801301 "PR:O14727 located_in GO:1904813"
xref: UniProtKB:O14727
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002194 ! apoptotic protease-activating factor 1
relationship: has_gene_template HGNC:576 ! APAF1 (human)

[Term]
id: PR:O14727-6
name: apoptotic protease-activating factor 1 isoform 6 (human)
def: "An apoptotic protease-activating factor 1 isoform 6 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hAPAF1/iso:6" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1-ALT (human)" EXACT [UniProtKB:O14727]
xref: UniProtKB:O14727-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002298 ! apoptotic protease-activating factor 1 isoform 6

[Term]
id: PR:O88879
name: apoptotic protease-activating factor 1 (mouse)
def: "An apoptotic protease-activating factor 1 that is encoded in the genome of mouse." [OMA:O88879, PRO:DNx]
comment: Category=organism-gene.
synonym: "Apaf1" RELATED Gene-based [UniProtKB:O88879]
synonym: "mAPAF1" EXACT PRO-short-label [PRO:DNx]
synonym: "APAF-1 (mouse)" EXACT [UniProtKB:O88879]
xref: UniProtKB:O88879
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002194 ! apoptotic protease-activating factor 1
relationship: has_gene_template MGI:1306796 ! Apaf1 (mouse)

[Term]
id: PR:O14727-4
name: apoptotic protease-activating factor 1 isoform 4 (human)
def: "An apoptotic protease-activating factor 1 isoform 4 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hAPAF1/iso:4" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1M (human)" EXACT [UniProtKB:O14727]
xref: UniProtKB:O14727-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002296 ! apoptotic protease-activating factor 1 isoform 4

[Term]
id: PR:O14727-5
name: apoptotic protease-activating factor 1 isoform 5 (human)
def: "An apoptotic protease-activating factor 1 isoform 5 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hAPAF1/iso:5" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1XS (human)" EXACT [UniProtKB:O14727]
xref: UniProtKB:O14727-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002297 ! apoptotic protease-activating factor 1 isoform 5

[Term]
id: PR:O14727-2
name: apoptotic protease-activating factor 1 isoform 2 (human)
def: "An apoptotic protease-activating factor 1 isoform 2 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hAPAF1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1L (human)" EXACT [UniProtKB:O14727]
xref: UniProtKB:O14727-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002294 ! apoptotic protease-activating factor 1 isoform 2

[Term]
id: PR:O14727-3
name: apoptotic protease-activating factor 1 isoform 3 (human)
def: "An apoptotic protease-activating factor 1 isoform 3 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hAPAF1/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1S (human)" EXACT [UniProtKB:O14727]
xref: UniProtKB:O14727-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002295 ! apoptotic protease-activating factor 1 isoform 3

[Term]
id: PR:O14727-1
name: apoptotic protease-activating factor 1 isoform 1 (human)
def: "An apoptotic protease-activating factor 1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hAPAF1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1XL (human)" EXACT [UniProtKB:O14727]
xref: UniProtKB:O14727-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002293 ! apoptotic protease-activating factor 1 isoform 1

[Term]
id: PR:000002194
name: apoptotic protease-activating factor 1
def: "A protein that is a translation product of the human APAF1 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "APAF1" EXACT PRO-short-label [PRO:DNx]
synonym: "APAF-1" EXACT []
synonym: "KIAA0413" RELATED Gene-based []
xref: PIRSF:PIRSF037646
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9I9H8
name: apoptotic protease-activating factor 1 (zebrafish)
def: "An apoptotic protease-activating factor 1 that is encoded in the genome of zebrafish." [PANTHER:PTHR22845:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "apaf1" RELATED Gene-based [UniProtKB:Q9I9H8]
synonym: "z-APAF1" EXACT PRO-short-label [PRO:DNx]
synonym: "APAF-1 (zebrafish)" EXACT [UniProtKB:Q9I9H8]
xref: UniProtKB:Q9I9H8
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000002194 ! apoptotic protease-activating factor 1
relationship: has_gene_template ZFIN:ZDB-GENE-000616-4 ! apaf1 (zebrafish)

[Term]
id: PR:O88879-2
name: apoptotic protease-activating factor 1 isoform 2 (mouse)
def: "An apoptotic protease-activating factor 1 isoform 2 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mAPAF1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88879-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002294 ! apoptotic protease-activating factor 1 isoform 2

[Term]
id: PR:000002298
name: apoptotic protease-activating factor 1 isoform 6
def: "An apoptotic protease-activating factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14727-6 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "Apaf-1-ALT" EXACT []
synonym: "APAF1/iso:6" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002194 ! apoptotic protease-activating factor 1

[Term]
id: PR:000002297
name: apoptotic protease-activating factor 1 isoform 5
def: "An apoptotic protease-activating factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14727-5 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "Apaf-1XS" EXACT []
synonym: "APAF1/iso:5" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002194 ! apoptotic protease-activating factor 1

[Term]
id: PR:000002296
name: apoptotic protease-activating factor 1 isoform 4
def: "An apoptotic protease-activating factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14727-4 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "Apaf-1M" EXACT []
synonym: "APAF1/iso:4" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002194 ! apoptotic protease-activating factor 1

[Term]
id: PR:000002295
name: apoptotic protease-activating factor 1 isoform 3
def: "An apoptotic protease-activating factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14727-3 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "Apaf-1S" EXACT []
synonym: "APAF1/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002194 ! apoptotic protease-activating factor 1

[Term]
id: PR:000002294
name: apoptotic protease-activating factor 1 isoform 2
def: "An apoptotic protease-activating factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14727-2 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "Apaf-1L" EXACT []
synonym: "APAF1/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002194 ! apoptotic protease-activating factor 1

[Term]
id: PR:000002293
name: apoptotic protease-activating factor 1 isoform 1
def: "An apoptotic protease-activating factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14727-1 or a 1:1 ortholog thereof." [PMID:10393175, PMID:10441496, PRO:JAN]
comment: Category=sequence.
synonym: "Apaf-1L" RELATED []
synonym: "Apaf-1XL" EXACT []
synonym: "APAF1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002194 ! apoptotic protease-activating factor 1

[Term]
id: PR:O88879-1
name: apoptotic protease-activating factor 1 isoform 1 (mouse)
def: "An apoptotic protease-activating factor 1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mAPAF1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "apoptotic protease-activating factor 1 isoform Apaf-1L (mouse)" EXACT [UniProtKB:O88879]
xref: UniProtKB:O88879-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002293 ! apoptotic protease-activating factor 1 isoform 1