[Term]
id: PR:000050105
name: caspase-7 subunit p20 (human)
def: "A caspase-7 subunit p20 in human. Example: UniProtKB:P55210-1, 24-198." [PRO:DNx, UniProtKB:P55210]
comment: Category=organism-modification.
synonym: "hCASP7/p20" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000004617" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P55210-1, 24-198" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002459 ! caspase-7 subunit p20

[Term]
id: PR:000050106
name: caspase-7 subunit p11 (human)
def: "A caspase-7 subunit p11 in human. Example: UniProtKB:P55210-1, 207-303." [PRO:DNx, UniProtKB:P55210]
comment: Category=organism-modification.
synonym: "hCASP7/p11" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000004619" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P55210-1, 207-303" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002458 ! caspase-7 subunit p11

[Term]
id: PR:000018767
name: caspase-7 proteolytic cleavage product
def: "A caspase-7 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "CASP7/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000002316 ! caspase-7

[Term]
id: PR:000002316
name: caspase-7
def: "A caspase-3-like protease that is a translation product of the human CASP7 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "MCH3" RELATED Gene-based []
synonym: "CASP7" EXACT PRO-short-label [PRO:DNx]
synonym: "CMH-1" EXACT []
synonym: "Lice2" RELATED Gene-based []
synonym: "CASP-7" EXACT []
synonym: "ICE-LAP3" EXACT []
synonym: "cysteine protease LICE2" EXACT []
synonym: "apoptotic protease Mch-3" EXACT []
synonym: "ICE-like apoptotic protease 3" EXACT []
xref: IUPHARobj:1623
is_a: PR:000002196 ! caspase-3-like protease

[Term]
id: PR:000002459
name: caspase-7 subunit p20
def: "A caspase-7 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P55210-1, 24-198." [PMID:8755496, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "CASP7/p20" EXACT PRO-short-label [PRO:DNx]
synonym: "Mch3 large subunit" EXACT []
is_a: PR:000002409 ! caspase-7 isoform 1
relationship: output_of GO:0016485 ! protein processing
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:000002458
name: caspase-7 subunit p11
def: "A caspase-7 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. Example: UniProtKB:P55210-1, 207-303." [PMID:8755496, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "CASP7/p11" EXACT PRO-short-label [PRO:DNx]
synonym: "Mch3 small subunit" EXACT []
is_a: PR:000002409 ! caspase-7 isoform 1
relationship: output_of GO:0016485 ! protein processing
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:P97864
name: caspase-7 (mouse)
def: "A caspase-7 that is encoded in the genome of mouse." [OMA:P97864, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mch3" RELATED Gene-based [UniProtKB:P97864]
synonym: "Casp7" RELATED Gene-based [UniProtKB:P97864]
synonym: "Lice2" RELATED Gene-based [UniProtKB:P97864]
synonym: "mCASP7" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP-7 (mouse)" EXACT [UniProtKB:P97864]
synonym: "cysteine protease LICE2 (mouse)" EXACT [UniProtKB:P97864]
synonym: "apoptotic protease Mch-3 (mouse)" EXACT [UniProtKB:P97864]
xref: UniProtKB:P97864
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002316 ! caspase-7
relationship: has_gene_template MGI:109383 ! Casp7 (mouse)

[Term]
id: PR:000002411
name: caspase-7 isoform 3
def: "A caspase-7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55210-3 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "CASP7/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-7 isoform alpha'" EXACT []
is_a: PR:000002316 ! caspase-7

[Term]
id: PR:000002410
name: caspase-7 isoform 2
def: "A caspase-7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55210-2 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "CASP7/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-7 isoform beta" EXACT []
is_a: PR:000002316 ! caspase-7

[Term]
id: PR:P55210-1
name: caspase-7 isoform Alpha (human)
def: "A caspase-7 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hCASP7/iso:Alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55210-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002409 ! caspase-7 isoform 1

[Term]
id: PR:P55210
name: caspase-7 (human)
def: "A caspase-7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P55210]
comment: Category=organism-gene.
synonym: "MCH3" RELATED Gene-based [UniProtKB:P55210]
synonym: "CASP7" RELATED Gene-based [UniProtKB:P55210]
synonym: "hCASP7" EXACT PRO-short-label [PRO:DNx]
synonym: "CMH-1 (human)" EXACT [UniProtKB:P55210]
synonym: "CASP-7 (human)" EXACT [UniProtKB:P55210]
synonym: "ICE-LAP3 (human)" EXACT [UniProtKB:P55210]
synonym: "apoptotic protease Mch-3 (human)" EXACT [UniProtKB:P55210]
synonym: "ICE-like apoptotic protease 3 (human)" EXACT [UniProtKB:P55210]
xref: Reactome:R-HSA-57029 "PR:P55210 located_in GO:0005829"
xref: UniProtKB:P55210
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002316 ! caspase-7
relationship: has_gene_template HGNC:1508 ! CASP7 (human)

[Term]
id: PR:P97864-1
name: caspase-7 isoform 1 (mouse)
def: "A caspase-7 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mCASP7/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97864-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002409 ! caspase-7 isoform 1

[Term]
id: PR:000018766
name: caspase-7, initiator methionine removed form
def: "A caspase-7 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "CASP7/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000002316 ! caspase-7
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000002409
name: caspase-7 isoform 1
def: "A caspase-7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55210-1 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "CASP7/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-7 isoform alpha" EXACT []
is_a: PR:000002316 ! caspase-7

[Term]
id: PR:P55210-3
name: caspase-7 isoform Alpha' (human)
def: "A caspase-7 isoform 3 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hCASP7/iso:Alpha'" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-7 isoform Beta (human)" RELATED [UniProtKB:P55210]
xref: UniProtKB:P55210-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002411 ! caspase-7 isoform 3

[Term]
id: PR:P55210-2
name: caspase-7 isoform Beta (human)
def: "A caspase-7 isoform 2 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hCASP7/iso:Beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55210-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002410 ! caspase-7 isoform 2

[Term]
id: PR:O01382
name: caspase (fruit fly)
def: "A caspase-7 that is encoded in the genome of fruit fly." [OMA:O01382, PRO:DNx]
comment: Category=organism-gene.
synonym: "ICE" RELATED Gene-based [UniProtKB:O01382]
synonym: "Drice" RELATED Gene-based [UniProtKB:O01382]
synonym: "CG7788" RELATED Gene-based [UniProtKB:O01382]
synonym: "fly-CASP7" EXACT PRO-short-label [PRO:DNx]
synonym: "drICE (fruit fly)" EXACT [UniProtKB:O01382]
xref: UniProtKB:O01382
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000002316 ! caspase-7
relationship: has_gene_template FlyBase:FBgn0019972 ! Drice (fruit fly)

[Term]
id: PR:P55210-4
name: caspase-7 isoform h4 (human)
def: "A caspase-7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55210-4." [PRO:DNx, UniProtKB:P55210]
comment: Category=organism-sequence.
synonym: "hCASP7/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55210-4
is_a: PR:P55210 ! caspase-7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens