[Term] id: PR:000002972 name: macrophage mannose receptor 1 def: "A C-type lectin with multiple lectin domains that is a translation product of the human MRC1 gene or a 1:1 ortholog thereof." [PMID:8297379, PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "MMR" EXACT [] synonym: "MRC1" EXACT PRO-short-label [PRO:DNx] synonym: "CD206" EXACT [] synonym: "MRC1L1" RELATED Gene-based [] synonym: "CLEC13D" RELATED Gene-based [] synonym: "CLEC13DL" RELATED Gene-based [] synonym: "C-type lectin domain family 13 member D" EXACT [] synonym: "C-type lectin domain family 13 member D-like" RELATED [] synonym: "macrophage mannose receptor 1-like protein 1" RELATED [] is_a: PR:000001025 ! C-type lectin with multiple lectin domains [Term] id: PR:Q61830 name: macrophage mannose receptor 1 (mouse) def: "A macrophage mannose receptor 1 that is encoded in the genome of mouse." [OMA:Q61830, PRO:DNx] comment: Category=organism-gene. synonym: "Mrc1" RELATED Gene-based [UniProtKB:Q61830] synonym: "mMRC1" EXACT PRO-short-label [PRO:DNx] synonym: "MMR (mouse)" EXACT [UniProtKB:Q61830] synonym: "CD206 (mouse)" EXACT [UniProtKB:Q61830] xref: UniProtKB:Q61830 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000002972 ! macrophage mannose receptor 1 relationship: has_gene_template MGI:97142 ! Mrc1 (mouse) [Term] id: PR:P22897-1 name: macrophage mannose receptor 1 isoform h1 (human) def: "A macrophage mannose receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22897-1." [PRO:DNx, UniProtKB:P22897] comment: Category=organism-sequence. synonym: "hMRC1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P22897-1 is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P22897-2 name: macrophage mannose receptor 1 isoform h2 (human) def: "A macrophage mannose receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22897-2." [PRO:DNx, UniProtKB:P22897] comment: Category=organism-sequence. synonym: "hMRC1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P22897-2 is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P22897 name: macrophage mannose receptor 1 (human) def: "A macrophage mannose receptor 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22897] comment: Category=organism-gene. synonym: "hMR" EXACT [UniProtKB:P22897] synonym: "MRC1" RELATED Gene-based [UniProtKB:P22897] synonym: "hMRC1" EXACT PRO-short-label [PRO:DNx] synonym: "MRC1L1" RELATED Gene-based [UniProtKB:P22897] synonym: "CLEC13D" RELATED Gene-based [UniProtKB:P22897] synonym: "CLEC13DL" RELATED Gene-based [UniProtKB:P22897] synonym: "MMR (human)" EXACT [UniProtKB:P22897] synonym: "CD206 (human)" EXACT [UniProtKB:P22897] synonym: "human mannose receptor" EXACT [UniProtKB:P22897] synonym: "C-type lectin domain family 13 member D (human)" EXACT [UniProtKB:P22897] synonym: "C-type lectin domain family 13 member D-like (human)" EXACT [UniProtKB:P22897] synonym: "macrophage mannose receptor 1-like protein 1 (human)" EXACT [UniProtKB:P22897] xref: UniProtKB:P22897 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002972 ! macrophage mannose receptor 1 relationship: has_gene_template HGNC:7228 ! MRC1 (human) [Term] id: PR:000048415 name: macrophage mannose receptor 1, signal peptide removed form (human) def: "A macrophage mannose receptor 1 (human) that has had the signal peptide removed. UniProtKB:P22897, 19-1456." [PRO:DNx, Reactome:R-HSA-1216515, Reactome:R-HSA-1236785, Reactome:R-HSA-1236818] comment: Category=organism-modification. synonym: "hMRC1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000017548" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:P22897, 19-1456" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1216515 "PR:000048415 located_in GO:0005886" xref: Reactome:R-HSA-1236785 "PR:000048415 located_in GO:0031901" xref: Reactome:R-HSA-1236818 "PR:000048415 located_in GO:0030669" intersection_of: PR:P22897 ! macrophage mannose receptor 1 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056201 name: macrophage mannose receptor 1 O-glycosylated 2 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1093 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-1093, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-1093, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056200 name: macrophage mannose receptor 1 O-glycosylated 1 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1093 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22897-1, Thr-1093, MOD:00005~GNO:G29068FM." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-1093, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056203 name: macrophage mannose receptor 1 O-glycosylated 4 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1221 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-1221, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-1221, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056202 name: macrophage mannose receptor 1 O-glycosylated 3 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-1221 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22897-1, Thr-1221, MOD:00005~GNO:G29068FM." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-1221, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056205 name: macrophage mannose receptor 1 O-glycosylated 6 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P22897-1, Thr-937, MOD:00005~GNO:G29068FM." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-937, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056204 name: macrophage mannose receptor 1 O-glycosylated 5 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-790 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-790, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-790, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000056206 name: macrophage mannose receptor 1 O-glycosylated 7 (human) def: "A macrophage mannose receptor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-937 of the amino acid sequence represented by UniProtKB:P22897-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P22897-1, Thr-937, MOD:00005~GNO:G43417UB." [GlyGen:P22897-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hMRC1/OGlyco:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P22897-1, Thr-937, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P22897 ! macrophage mannose receptor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens