[Term]
id: PR:Q60989
name: E3 ubiquitin-protein ligase XIAP (mouse)
def: "A baculoviral IAP repeat-containing protein 4 that is encoded in the genome of mouse." [OMA:Q60989, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aipa" RELATED Gene-based [UniProtKB:Q60989]
synonym: "Api3" RELATED Gene-based [UniProtKB:Q60989]
synonym: "Miha" RELATED Gene-based [UniProtKB:Q60989]
synonym: "Xiap" RELATED Gene-based [UniProtKB:Q60989]
synonym: "Birc4" RELATED Gene-based [UniProtKB:Q60989]
synonym: "mIAP3" EXACT [UniProtKB:Q60989]
synonym: "mXIAP" EXACT PRO-short-label [PRO:DNx]
synonym: "mIAP-3" EXACT [UniProtKB:Q60989]
synonym: "IAP-3 (mouse)" EXACT [UniProtKB:Q60989]
synonym: "X-linked IAP (mouse)" EXACT [UniProtKB:Q60989]
synonym: "IAP homolog A (mouse)" EXACT [UniProtKB:Q60989]
synonym: "inhibitor of apoptosis protein 3 (mouse)" EXACT [UniProtKB:Q60989]
synonym: "RING-type E3 ubiquitin transferase XIAP (mouse)" EXACT [UniProtKB:Q60989]
synonym: "X-linked inhibitor of apoptosis protein (mouse)" EXACT [UniProtKB:Q60989]
synonym: "baculoviral IAP repeat-containing protein 4 (mouse)" EXACT [UniProtKB:Q60989]
xref: UniProtKB:Q60989
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003119 ! baculoviral IAP repeat-containing protein 4
relationship: has_gene_template MGI:107572 ! Xiap (mouse)

[Term]
id: PR:Q9R0I6
name: E3 ubiquitin-protein ligase XIAP (rat)
def: "A baculoviral IAP repeat-containing protein 4 that is encoded in the genome of rat." [PANTHER:PTHR10044:SF10, PRO:DNx]
comment: Category=organism-gene.
synonym: "Api3" RELATED Gene-based [UniProtKB:Q9R0I6]
synonym: "Xiap" RELATED Gene-based [UniProtKB:Q9R0I6]
synonym: "Birc4" RELATED Gene-based [UniProtKB:Q9R0I6]
synonym: "rIAP3" EXACT [UniProtKB:Q9R0I6]
synonym: "rXIAP" EXACT PRO-short-label [PRO:DNx]
synonym: "rIAP-3" EXACT [UniProtKB:Q9R0I6]
synonym: "IAP-3 (rat)" EXACT [UniProtKB:Q9R0I6]
synonym: "X-linked IAP (rat)" EXACT [UniProtKB:Q9R0I6]
synonym: "IAP homolog A (rat)" EXACT [UniProtKB:Q9R0I6]
synonym: "inhibitor of apoptosis protein 3 (rat)" EXACT [UniProtKB:Q9R0I6]
synonym: "RING-type E3 ubiquitin transferase XIAP (rat)" EXACT [UniProtKB:Q9R0I6]
synonym: "X-linked inhibitor of apoptosis protein (rat)" EXACT [UniProtKB:Q9R0I6]
synonym: "baculoviral IAP repeat-containing protein 4 (rat)" EXACT [UniProtKB:Q9R0I6]
xref: UniProtKB:Q9R0I6
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003119 ! baculoviral IAP repeat-containing protein 4
relationship: has_gene_template RGD:620692 ! Xiap (rat)

[Term]
id: PR:P98170
name: E3 ubiquitin-protein ligase XIAP (human)
def: "A baculoviral IAP repeat-containing protein 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P98170]
comment: Category=organism-gene.
synonym: "API3" RELATED Gene-based [UniProtKB:P98170]
synonym: "IAP3" RELATED Gene-based [UniProtKB:P98170]
synonym: "XIAP" RELATED Gene-based [UniProtKB:P98170]
synonym: "hILP" EXACT [UniProtKB:P98170]
synonym: "BIRC4" RELATED Gene-based [UniProtKB:P98170]
synonym: "hIAP3" EXACT [UniProtKB:P98170]
synonym: "hXIAP" EXACT PRO-short-label [PRO:DNx]
synonym: "hIAP-3" EXACT [UniProtKB:P98170]
synonym: "ILP (human)" EXACT [UniProtKB:P98170]
synonym: "IAP-3 (human)" EXACT [UniProtKB:P98170]
synonym: "X-linked IAP (human)" EXACT [UniProtKB:P98170]
synonym: "IAP-like protein (human)" EXACT [UniProtKB:P98170]
synonym: "inhibitor of apoptosis protein 3 (human)" EXACT [UniProtKB:P98170]
synonym: "RING-type E3 ubiquitin transferase XIAP (human)" EXACT [UniProtKB:P98170]
synonym: "X-linked inhibitor of apoptosis protein (human)" EXACT [UniProtKB:P98170]
synonym: "baculoviral IAP repeat-containing protein 4 (human)" EXACT [UniProtKB:P98170]
xref: Reactome:R-HSA-50849 "PR:P98170 located_in GO:0005829"
xref: Reactome:R-HSA-3322366 "PR:P98170 located_in GO:0005654"
xref: UniProtKB:P98170
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003119 ! baculoviral IAP repeat-containing protein 4
relationship: has_gene_template HGNC:592 ! XIAP (human)

[Term]
id: PR:000003119
name: baculoviral IAP repeat-containing protein 4
def: "A protein that is a translation product of the human XIAP gene or a 1:1 ortholog thereof. Potent negative regulator of apoptosis." [PRO:CNA]
comment: Category=gene.
synonym: "ILP" EXACT []
synonym: "API3" RELATED Gene-based []
synonym: "Aipa" RELATED Gene-based []
synonym: "IAP3" RELATED Gene-based []
synonym: "Miha" RELATED Gene-based []
synonym: "XIAP" EXACT PRO-short-label [PRO:DNx]
synonym: "BIRC4" RELATED Gene-based []
synonym: "IAP-3" EXACT []
synonym: "X-linked IAP" EXACT []
synonym: "IAP homolog A" EXACT []
synonym: "IAP-like protein" EXACT []
synonym: "E3 ubiquitin-protein ligase XIAP" EXACT []
synonym: "inhibitor of apoptosis protein 3" EXACT []
synonym: "RING-type E3 ubiquitin transferase XIAP" EXACT []
synonym: "X-linked inhibitor of apoptosis protein" EXACT []
xref: IUPHARobj:2790
is_a: PR:000000001 ! protein

[Term]
id: PR:P98170-1
name: E3 ubiquitin-protein ligase XIAP isoform 1 (human)
def: "A baculoviral IAP repeat-containing protein 4 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hXIAP/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P98170-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003120 ! baculoviral IAP repeat-containing protein 4 isoform 1

[Term]
id: PR:Q60989-1
name: E3 ubiquitin-protein ligase XIAP isoform 1 (mouse)
def: "A baculoviral IAP repeat-containing protein 4 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mXIAP/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q60989-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003120 ! baculoviral IAP repeat-containing protein 4 isoform 1

[Term]
id: PR:000049706
name: E3 ubiquitin-protein ligase XIAP ubiquitinated form (human)
def: "An E3 ubiquitin-protein ligase XIAP (human) that includes at least one ubiquitinated lysine. UniProtKB:P98170, MOD:01148." [PRO:DNx, Reactome:R-HSA-5675477]
comment: Category=organism-modification.
synonym: "hXIAP/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P98170, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5675477 "PR:000049706 located_in GO:0005829"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:P98170 ! E3 ubiquitin-protein ligase XIAP (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000003122
name: baculoviral IAP repeat-containing protein 4 isoform 1 phosphorylated form
def: "A baculoviral IAP repeat-containing protein 4 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "XIAP/iso:1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000003120 ! baculoviral IAP repeat-containing protein 4 isoform 1

[Term]
id: PR:000003123
name: baculoviral IAP repeat-containing protein 4 isoform 1 phosphorylated 1
def: "A baculoviral IAP repeat-containing protein 4 isoform 1 phosphorylated form in which the phosphorylation occurs at a Ser residue by the action of AKT kinase, AKT1 or AKT2. Example: UniProtKB:P98170-1, Ser-87, MOD:00046." [PMID:14645242, PRO:JAN]
comment: Category=modification.
synonym: "XIAP/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003122 ! baculoviral IAP repeat-containing protein 4 isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000003120
name: baculoviral IAP repeat-containing protein 4 isoform 1
def: "A baculoviral IAP repeat-containing protein 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98170-1 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "XIAP/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003119 ! baculoviral IAP repeat-containing protein 4