[Term]
id: PR:Q9NR28
name: diablo IAP-binding mitochondrial protein (human)
def: "A diablo IAP-binding mitochondrial protein that is encoded in the genome of human." [PRO:CNx, UniProtKB:Q9NR28]
comment: Category=organism-gene.
synonym: "SMAC" RELATED Gene-based [UniProtKB:Q9NR28]
synonym: "DIABLO" RELATED Gene-based [UniProtKB:Q9NR28]
synonym: "hDIABLO" EXACT PRO-short-label [PRO:DNx]
synonym: "diablo homolog, mitochondrial (human)" EXACT [UniProtKB:Q9NR28]
synonym: "direct IAP-binding protein with low pI (human)" EXACT [UniProtKB:Q9NR28]
synonym: "second mitochondria-derived activator of caspase (human)" EXACT [UniProtKB:Q9NR28]
xref: UniProtKB:Q9NR28
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003130 ! diablo IAP-binding mitochondrial protein
relationship: has_gene_template HGNC:21528 ! DIABLO (human)

[Term]
id: PR:000047176
name: diablo IAP-binding mitochondrial protein, transit peptide removed form (human)
def: "A diablo IAP-binding mitochondrial protein (human) that has had the transit peptide removed. UniProtKB:Q9NR28, 56-239." [PRO:DNx, Reactome:R-HSA-114298, Reactome:R-HSA-64637]
comment: Category=organism-modification.
synonym: "PRO_0000021072" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDIABLO/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NR28, 56-239" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-114298 "PR:000047176 located_in GO:0005829"
xref: Reactome:R-HSA-64637 "PR:000047176 located_in GO:0005758"
intersection_of: PR:Q9NR28 ! diablo IAP-binding mitochondrial protein (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9JIQ3
name: diablo IAP-binding mitochondrial protein (mouse)
def: "A diablo IAP-binding mitochondrial protein that is encoded in the genome of mouse." [OMA:Q9JIQ3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Smac" RELATED Gene-based [UniProtKB:Q9JIQ3]
synonym: "Diablo" RELATED Gene-based [UniProtKB:Q9JIQ3]
synonym: "mDIABLO" EXACT PRO-short-label [PRO:DNx]
synonym: "diablo homolog, mitochondrial (mouse)" EXACT [UniProtKB:Q9JIQ3]
synonym: "direct IAP-binding protein with low pI (mouse)" EXACT [UniProtKB:Q9JIQ3]
synonym: "second mitochondria-derived activator of caspase (mouse)" EXACT [UniProtKB:Q9JIQ3]
xref: UniProtKB:Q9JIQ3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003130 ! diablo IAP-binding mitochondrial protein
relationship: has_gene_template MGI:1913843 ! Diablo (mouse)

[Term]
id: PR:Q9NR28-2
name: diablo IAP-binding mitochondrial protein isoform 2 (human)
def: "A diablo IAP-binding mitochondrial protein isoform 2 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hDIABLO/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "diablo IAP-binding mitochondrial protein isoform Diablo-S (human)" EXACT [UniProtKB:Q9NR28]
xref: UniProtKB:Q9NR28-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003132 ! diablo IAP-binding mitochondrial protein isoform 2

[Term]
id: PR:Q9NR28-3
name: diablo IAP-binding mitochondrial protein isoform h3 (human)
def: "A diablo IAP-binding mitochondrial protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR28-3." [PRO:DNx, UniProtKB:Q9NR28]
comment: Category=organism-sequence.
synonym: "hDIABLO/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "diablo IAP-binding mitochondrial protein isoform SMAC3 (human)" EXACT [UniProtKB:Q9NR28]
xref: UniProtKB:Q9NR28-3
is_a: PR:Q9NR28 ! diablo IAP-binding mitochondrial protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000025426
name: diablo IAP-binding mitochondrial protein proteolytic cleavage product
def: "A diablo IAP-binding mitochondrial protein that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "DIABLO/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000003130 ! diablo IAP-binding mitochondrial protein

[Term]
id: PR:Q9NR28-1
name: diablo IAP-binding mitochondrial protein isoform 1 (human)
def: "A diablo IAP-binding mitochondrial protein isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hDIABLO/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NR28-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003131 ! diablo IAP-binding mitochondrial protein isoform 1

[Term]
id: PR:Q9JIQ3-1
name: diablo IAP-binding mitochondrial protein isoform 1 (mouse)
def: "A diablo IAP-binding mitochondrial protein isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "mDIABLO/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JIQ3-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003131 ! diablo IAP-binding mitochondrial protein isoform 1

[Term]
id: PR:000018786
name: diablo IAP-binding mitochondrial protein, transit peptide removed form
def: "A diablo IAP-binding mitochondrial protein that has had the transit peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "DIABLO/TransPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003130 ! diablo IAP-binding mitochondrial protein
intersection_of: lacks_part SO:0000725 ! transit_peptide

[Term]
id: PR:000003131
name: diablo IAP-binding mitochondrial protein isoform 1
def: "A diablo IAP-binding mitochondrial protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR28-1 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "DIABLO/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003130 ! diablo IAP-binding mitochondrial protein

[Term]
id: PR:000003130
name: diablo IAP-binding mitochondrial protein
def: "A protein that is a translation product of the human DIABLO gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "SMAC" RELATED Gene-based []
synonym: "Smac" EXACT []
synonym: "DIABLO" EXACT PRO-short-label [PRO:DNx]
synonym: "diablo homolog, mitochondrial" EXACT []
synonym: "direct IAP-binding protein with low pI" EXACT []
synonym: "second mitochondria-derived activator of caspase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000003132
name: diablo IAP-binding mitochondrial protein isoform 2
def: "A diablo IAP-binding mitochondrial protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR28-2 or a 1:1 ortholog thereof." [PRO:JAN]
comment: Category=sequence.
synonym: "diablo-S" EXACT []
synonym: "DIABLO/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "diablo short isoform" EXACT []
is_a: PR:000003130 ! diablo IAP-binding mitochondrial protein

[Term]
id: PR:000003135
name: diablo IAP-binding mitochondrial protein isoform 1, transit peptide removed form
def: "A diablo IAP-binding mitochondrial protein isoform 1 that has had the transit peptide removed." [PRO:JAN]
comment: Category=modification.
synonym: "diablo mature" EXACT []
synonym: "DIABLO/iso:1/TransPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003131 ! diablo IAP-binding mitochondrial protein isoform 1
intersection_of: lacks_part SO:0000725 ! transit_peptide

[Term]
id: PR:000036235
name: diablo IAP-binding mitochondrial protein acetylated 1 (human)
def: "A diablo IAP-binding mitochondrial protein that is N-terminal Met acetylated in human. Example: UniProtKB:Q9NR28-1, Met-1, MOD:00058." [TDR:2171]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hDIABLO/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NR28-1, Met-1, MOD:00058" NARROW PRO-proteoform-std [PRO:DNx]
xref: TDR:2171
is_a: PR:000003130 ! diablo IAP-binding mitochondrial protein
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens