[Term]
id: PR:P09958-1
name: furin isoform 1 (human)
def: "A furin isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hFURIN/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09958-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003147 ! furin isoform 1

[Term]
id: PR:P09958
name: furin (human)
def: "A furin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P09958]
comment: Category=organism-gene.
synonym: "FUR" RELATED Gene-based [UniProtKB:P09958]
synonym: "PACE" RELATED Gene-based [UniProtKB:P09958]
synonym: "FURIN" RELATED Gene-based [UniProtKB:P09958]
synonym: "PCSK3" RELATED Gene-based [UniProtKB:P09958]
synonym: "hFURIN" EXACT PRO-short-label [PRO:DNx]
synonym: "dibasic-processing enzyme (human)" EXACT [UniProtKB:P09958]
synonym: "paired basic amino acid residue-cleaving enzyme (human)" EXACT [UniProtKB:P09958]
xref: UniProtKB:P09958
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003137 ! furin
relationship: has_gene_template HGNC:8568 ! FURIN (human)

[Term]
id: PR:000035903
name: furin active form (human)
def: "A furin active form in human. UniProtKB:P09958, 108-794." [PMID:1629222, Reactome:R-HSA-1181103, Reactome:R-HSA-157049, Reactome:R-HSA-2159856, Reactome:R-HSA-448351]
comment: Category=organism-modification.
synonym: "hFURIN/active" EXACT PRO-short-label [PRO:DAN]
synonym: "PRO_0000027029" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P09958, 108-794" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-157049 "PR:000035903 located_in GO:0000139"
xref: Reactome:R-HSA-448351 "PR:000035903 located_in GO:0005796"
xref: Reactome:R-HSA-2159856 "PR:000035903 located_in GO:0005886"
xref: Reactome:R-HSA-1181103 "PR:000035903 located_in GO:0005576"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003150 ! furin active form

[Term]
id: PR:000003137
name: furin
def: "A subtilisin/kexin-type proprotein convertase that is a translation product of the human FURIN gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "FUR" RELATED Gene-based []
synonym: "PACE" RELATED Gene-based []
synonym: "FURIN" EXACT PRO-short-label [PRO:DNx]
synonym: "PCSK3" RELATED Gene-based []
synonym: "prohormone convertase 3" RELATED []
synonym: "dibasic-processing enzyme" EXACT []
synonym: "paired basic amino acid residue-cleaving enzyme" EXACT []
xref: IUPHARobj:2366
is_a: PR:000003136 ! subtilisin/kexin-type proprotein convertase