[Term] id: PR:000027209 name: caveolin-1 isoform 1 def: "A caveolin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03135-1 or a 1:1 ortholog thereof." [PRO:PD] comment: Category=sequence. synonym: "CAV1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003198 ! caveolin-1 [Term] id: PR:000003198 name: caveolin-1 def: "A protein that is a translation product of the human CAV1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "CAV" RELATED Gene-based [] synonym: "CAV1" EXACT PRO-short-label [PRO:DNx] xref: PIRSF:PIRSF009396 is_a: PR:000000001 ! protein [Term] id: PR:Q03135-2 name: caveolin-1 isoform h2 (human) def: "A caveolin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03135-2." [PRO:DNx, UniProtKB:Q03135] comment: Category=organism-sequence. synonym: "hCAV1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03135-2 is_a: PR:Q03135 ! caveolin-1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q03135-1 name: caveolin-1 isoform 1 (human) def: "A caveolin-1 isoform 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-sequence. synonym: "hCAV1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03135-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027209 ! caveolin-1 isoform 1 [Term] id: PR:000039609 name: caveolin-1 isoform 2 def: "A caveolin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49817-2 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "CAV1/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003198 ! caveolin-1 [Term] id: PR:000046576 name: caveolin-1, initiator methionine removed form (human) def: "A caveolin-1 (human) that has had the initiator methionine removed. UniProtKB:Q03135, 2-178." [PRO:DNx, Reactome:R-HSA-163510, Reactome:R-HSA-204504, Reactome:R-HSA-534994, Reactome:R-HSA-535009, Reactome:R-HSA-5368451] comment: Category=organism-modification. synonym: "PRO_0000004764" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hCAV1/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q03135, 2-178" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-204504 "PR:000046576 located_in GO:0000139" xref: Reactome:R-HSA-163510 "PR:000046576 located_in GO:0005811" xref: Reactome:R-HSA-534994 "PR:000046576 located_in GO:0005886" xref: Reactome:R-HSA-535009 "PR:000046576 located_in GO:0030666" xref: Reactome:R-HSA-5368451 "PR:000046576 located_in GO:0031901" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q03135 ! caveolin-1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P35431-2 name: caveolin-1 isoform Beta (chicken) def: "A caveolin-1 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35431-2." [PRO:DNx, UniProtKB:P35431] comment: Category=organism-sequence. synonym: "chick-CAV1/iso:Beta" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35431-2 is_a: PR:P35431 ! caveolin-1 (chicken) relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus [Term] id: PR:000027212 name: caveolin-1 isoform 1 phosphorylated 1 (human) def: "A caveolin-1 isoform 1 phosphorylated 1 in human. UniProtKB:Q03135-1, Tyr-14, MOD:00048." [PMID:18789131, PRO:PD] comment: Category=organism-modification. synonym: "hCAV1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q03135-1, Tyr-14, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027211 ! caveolin-1 isoform 1 phosphorylated 1 relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine [Term] id: PR:P49817-1 name: caveolin-1 isoform 1 (mouse) def: "A caveolin-1 isoform 1 that is encoded in the genome of mouse." [PRO:PD] comment: Category=organism-sequence. synonym: "mCAV1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P49817-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000027209 ! caveolin-1 isoform 1 [Term] id: PR:P41350 name: caveolin-1 (rat) def: "A caveolin-1 that is encoded in the genome of rat." [PANTHER:PTHR10844:SF5, PRO:DNx] comment: Category=organism-gene. synonym: "Cav" RELATED Gene-based [UniProtKB:P41350] synonym: "Cav1" RELATED Gene-based [UniProtKB:P41350] synonym: "rCAV1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P41350 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000003198 ! caveolin-1 relationship: has_gene_template RGD:2280 ! Cav1 (rat) [Term] id: PR:000027211 name: caveolin-1 isoform 1 phosphorylated 1 def: "A caveolin-1 isoform 1 that has been post-translationally modified to include a phosphorylated Tyr residue as a result of Src kinase activation. Example: UniProtKB:Q03135-1, Tyr-14, MOD:00048." [PMID:18789131, PRO:PD] comment: Category=modification. synonym: "CAV1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000027209 ! caveolin-1 isoform 1 relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine [Term] id: PR:P49817-2 name: caveolin-1 isoform 2 (mouse) def: "A caveolin-1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mCAV1/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P49817-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039609 ! caveolin-1 isoform 2 [Term] id: PR:P41350-2 name: caveolin-1 isoform 2 (rat) def: "A caveolin-1 isoform 2 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rCAV1/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P41350-2 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039609 ! caveolin-1 isoform 2 [Term] id: PR:P41350-1 name: caveolin-1 isoform r1 (rat) def: "A caveolin-1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41350-1." [PRO:DNx, UniProtKB:P41350] comment: Category=organism-sequence. synonym: "rCAV1/iso:r1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P41350-1 is_a: PR:P41350 ! caveolin-1 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:000045807 name: caveolin-1 phosphorylated 1 (mouse) def: "A caveolin-1 (mouse) that has been phosphorylated on the residue at the position equivalent to Tyr-14 of the amino acid sequence represented by UniProtKB:P49817-1. Example: UniProtKB:P49817-1, Tyr-14, MOD:00048." [PMID:11094059, iPTMnet:P49817] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11094059). Status=unreviewed. synonym: "mCAV1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P49817-1, Tyr-14, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P49817 ! caveolin-1 (mouse) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P49817 name: caveolin-1 (mouse) def: "A caveolin-1 that is encoded in the genome of mouse." [OMA:P49817, PRO:DNx] comment: Category=organism-gene. synonym: "Cav" RELATED Gene-based [UniProtKB:P49817] synonym: "Cav1" RELATED Gene-based [UniProtKB:P49817] synonym: "mCAV1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P49817 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003198 ! caveolin-1 relationship: has_gene_template MGI:102709 ! Cav1 (mouse) [Term] id: PR:P35431-1 name: caveolin-1 isoform Alpha (chicken) def: "A caveolin-1 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35431-1." [PRO:DNx, UniProtKB:P35431] comment: Category=organism-sequence. synonym: "chick-CAV1/iso:Alpha" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35431-1 is_a: PR:P35431 ! caveolin-1 (chicken) relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus [Term] id: PR:Q03135 name: caveolin-1 (human) def: "A caveolin-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q03135] comment: Category=organism-gene. synonym: "CAV" RELATED Gene-based [UniProtKB:Q03135] synonym: "CAV1" RELATED Gene-based [UniProtKB:Q03135] synonym: "hCAV1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03135 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003198 ! caveolin-1 relationship: has_gene_template HGNC:1527 ! CAV1 (human) [Term] id: PR:P35431 name: caveolin-1 (chicken) def: "A caveolin-1 that is encoded in the genome of chicken." [OMA:P35431, PRO:DNx] comment: Category=organism-gene. synonym: "CAV1" RELATED Gene-based [UniProtKB:P35431] synonym: "chick-CAV1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35431 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000003198 ! caveolin-1 relationship: has_gene_template NCBIGene:373996 ! CAV1 (chicken) [Term] id: PR:000018789 name: caveolin-1, initiator methionine removed form def: "A caveolin-1 that has had the initiator methionine removed." [PRO:DNx] comment: Category=modification. synonym: "CAV1/InitMet-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000003198 ! caveolin-1 intersection_of: lacks_part PR:000021937 ! initiator methionine