[Term] id: PR:000051372 name: antithrombin-III O-glycosylated 1 (human) def: "An antithrombin-III (human) that has been O-glycosylated at the residue equivalent to Thr-418 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01008-1, Thr-418, MOD:00005~GNO:G29068FM." [GlyGen:P01008-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Thr-418, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01008-1 name: antithrombin-III isoform 1 (human) def: "An antithrombin-III isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hSERPINC1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P01008-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003253 ! antithrombin-III isoform 1 [Term] id: PR:000049206 name: antithrombin-III, signal peptide removed form (human) def: "An antithrombin-III (human) that has had the signal peptide removed. UniProtKB:P01008, 33-464." [PRO:DNx, Reactome:R-HSA-140792, Reactome:R-HSA-140807] comment: Category=organism-modification. synonym: "PRO_0000032489" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hSERPINC1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008, 33-464" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-140792 "PR:000049206 located_in GO:0005886" xref: Reactome:R-HSA-140807 "PR:000049206 located_in GO:0005576" xref: Reactome:R-HSA-8956773 "PR:000049206 located_in GO:0005788" intersection_of: PR:P01008 ! antithrombin-III (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000051367 name: antithrombin-III N-glycosylated 2 (human) def: "An antithrombin-III (human) that has been N-glycosylated at the residue equivalent to Asn-128 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P01008-1, Asn-128, MOD:00160~GNO:G42358LZ." [GlyGen:P01008-1, PMID:24279413, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-128, MOD:00160~GNO:G42358LZ" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-128, MOD:00160~UniCarbKB:4923" NARROW [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G42358LZ ! G42358LZ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000051366 name: antithrombin-III N-glycosylated 1 (human) def: "An antithrombin-III (human) that has been N-glycosylated at the residue equivalent to Asn-128 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01008-1, Asn-128, MOD:00160~GNO:G00912UN." [GlyGen:P01008-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-128, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01008 name: antithrombin-III (human) def: "An antithrombin-III that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01008] comment: Category=organism-gene. synonym: "AT3" RELATED Gene-based [UniProtKB:P01008] synonym: "PRO0309" RELATED Gene-based [UniProtKB:P01008] synonym: "SERPINC1" RELATED Gene-based [UniProtKB:P01008] synonym: "hSERPINC1" EXACT PRO-short-label [PRO:DNx] synonym: "ATIII (human)" EXACT [UniProtKB:P01008] synonym: "serpin C1 (human)" EXACT [UniProtKB:P01008] xref: UniProtKB:P01008 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003252 ! antithrombin-III relationship: has_gene_template HGNC:775 ! SERPINC1 (human) [Term] id: PR:000051370 name: antithrombin-III N-glycosylated 5 (human) def: "An antithrombin-III (human) that has been N-glycosylated at the residue equivalent to Asn-187 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01008-1, Asn-187, MOD:00160~GNO:G88374WZ." [GlyGen:P01008-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/NGlyco:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-187, MOD:00160~GNO:G88374WZ" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G88374WZ ! G88374WZ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000051371 name: antithrombin-III N-glycosylated 6 (human) def: "An antithrombin-III (human) that has been N-glycosylated at the residue equivalent to Asn-224 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01008-1, Asn-224, MOD:00160~GNO:G00912UN." [GlyGen:P01008-1, PMID:24841998, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/NGlyco:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-224, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000003252 name: antithrombin-III def: "A serpin that is a translation product of the human SERPINC1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "AT3" RELATED Gene-based [] synonym: "ATIII" EXACT [] synonym: "PRO0309" RELATED Gene-based [] synonym: "SERPINC1" EXACT PRO-short-label [PRO:DNx] synonym: "serpin C1" EXACT [] xref: IUPHARobj:2632 is_a: PR:000025875 ! serpin [Term] id: PR:000051373 name: antithrombin-III O-glycosylated 2 (human) def: "An antithrombin-III (human) that has been O-glycosylated at the residue equivalent to Thr-418 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01008-1, Thr-418, MOD:00005~GNO:G43417UB." [GlyGen:P01008-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Thr-418, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000051369 name: antithrombin-III N-glycosylated 4 (human) def: "An antithrombin-III (human) that has been N-glycosylated at the residue equivalent to Asn-187 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan structure is represented by GlyTouCan:G22140GZ. Example: UniProtKB:P01008-1, Asn-187, MOD:00160~GNO:G22140GZ." [GlyGen:P01008-1, PMID:19838169, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/NGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-187, MOD:00160~GNO:G22140GZ" NARROW PRO-proteoform-std [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-187, MOD:00160~UniCarbKB:3539" NARROW [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G22140GZ ! G22140GZ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000051368 name: antithrombin-III N-glycosylated 3 (human) def: "An antithrombin-III (human) that has been N-glycosylated at the residue equivalent to Asn-187 of the amino acid sequence represented by UniProtKB:P01008-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01008-1, Asn-187, MOD:00160~GNO:G00912UN." [GlyGen:P01008-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINC1/NGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P01008-1, Asn-187, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P01008 ! antithrombin-III (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens