[Term] id: PR:P34556 name: cyclin-dependent kinase 1 (worm) def: "A cyclin-dependent kinase 1 that is encoded in the genome of worm." [OMA:P34556, PANTHER:PTHR24056:SF123, PRO:DNx] comment: Category=organism-gene. synonym: "cdk-1" RELATED Gene-based [UniProtKB:P34556] synonym: "ncc-1" RELATED Gene-based [UniProtKB:P34556] synonym: "T05G5.3" RELATED Gene-based [UniProtKB:P34556] synonym: "CDK1 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "p34 protein kinase (worm)" EXACT [UniProtKB:P34556] synonym: "cell division protein kinase 1 (worm)" EXACT [UniProtKB:P34556] synonym: "cell division control protein 2 homolog (worm)" EXACT [UniProtKB:P34556] xref: UniProtKB:P34556 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000003271 ! cyclin-dependent kinase 1 relationship: has_gene_template WormBase:WBGene00000405 ! cdk-1 (worm) [Term] id: PR:000046137 name: cyclin-dependent kinase 1 phosphorylated 1 (mouse) def: "A cyclin-dependent kinase 1 (mouse) that has been phosphorylated at Tyr-15. UniProtKB:P11440, Tyr-15, MOD:00048." [PMID:23616086, iPTMnet:P11440] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23616086). Status=unreviewed. synonym: "mCDK1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P11440, Tyr-15, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P11440 ! cyclin-dependent kinase 1 (mouse) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P39951 name: cyclin-dependent kinase 1 (rat) def: "A cyclin-dependent kinase 1 that is encoded in the genome of rat." [OMA:P39951, PANTHER:PTHR24056:SF123, PRO:DNx] comment: Category=organism-gene. synonym: "Cdc2" RELATED Gene-based [UniProtKB:P39951] synonym: "Cdk1" RELATED Gene-based [UniProtKB:P39951] synonym: "Cdc2a" RELATED Gene-based [UniProtKB:P39951] synonym: "Cdkn1" RELATED Gene-based [UniProtKB:P39951] synonym: "rCDK1" EXACT PRO-short-label [PRO:DNx] synonym: "CDK1 (rat)" EXACT [UniProtKB:P39951] synonym: "p34 protein kinase (rat)" EXACT [UniProtKB:P39951] synonym: "cell division protein kinase 1 (rat)" EXACT [UniProtKB:P39951] synonym: "cell division control protein 2 homolog (rat)" EXACT [UniProtKB:P39951] xref: UniProtKB:P39951 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000003271 ! cyclin-dependent kinase 1 relationship: has_gene_template RGD:2319 ! Cdk1 (rat) [Term] id: PR:000003271 name: cyclin-dependent kinase 1 def: "A CDK2-related kinase that is a translation product of the human CDK1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "CDC2" RELATED Gene-based [] synonym: "CDK1" EXACT PRO-short-label [PRO:DNx] synonym: "CDKN1" RELATED Gene-based [] synonym: "CDC28A" RELATED Gene-based [] synonym: "P34CDC2" RELATED Gene-based [] synonym: "p33 protein kinase" RELATED [PRO:DAN] synonym: "p34 protein kinase" RELATED [PRO:DAN] synonym: "cell division protein kinase 1" EXACT [] synonym: "Cell division control protein 2 homolog" EXACT [] xref: IUPHARobj:1961 is_a: PR:000003270 ! CDK2-related kinase [Term] id: PR:000026211 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human) def: "A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066] comment: Category=organism-modification. synonym: "hCDK1/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "phospho-Cdc2 (Thr 161)" EXACT [] synonym: "UniProtKB:P06493-1, Thr-161, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-157415 "PR:000026211 located_in GO:0005829" xref: Reactome:R-HSA-170066 "PR:000026211 located_in GO:0005654" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026182 ! cyclin-dependent kinase 1 isoform 1 phosphorylated 2 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000026213 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (mouse) def: "A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:P11440-1, Thr-14, MOD:00047." [PMID:17242355] comment: Category=organism-modification. synonym: "mCDK1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P11440-1, Thr-14, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000026180 ! cyclin-dependent kinase 1 isoform 1 phosphorylated 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000026212 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (mouse) def: "A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in mouse. UniProtKB:P11440-1, Thr-161, MOD:00047." [PMID:17242355] comment: Category=organism-modification. synonym: "mCDK1/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P11440-1, Thr-161, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000026182 ! cyclin-dependent kinase 1 isoform 1 phosphorylated 2 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000027124 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 4 (human) def: "A cyclin-dependent kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074] comment: Category=organism-modification. synonym: "hCDK1/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "phospho-Cdc2(Thr 161, Thr 14, Tyr 15) (human)" EXACT [Reactome:R-HSA-170071, Reactome:R-HSA-170074] synonym: "UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-170071 "PR:000027124 located_in GO:0005829" xref: Reactome:R-HSA-170074 "PR:000027124 located_in GO:0005654" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027122 ! cyclin-dependent kinase 1 isoform 1 phosphorylated 4 relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine [Term] id: PR:000027125 name: cyclin-dependent kinase 1 phosphorylated form def: "A cyclin-dependent kinase 1 that includes at least one phosphorylated residue." [PRO:DAN] comment: Category=modification. synonym: "CDK1/PhosRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: has_part MOD:00696 ! phosphorylated residue intersection_of: PR:000003271 ! cyclin-dependent kinase 1 [Term] id: PR:000027126 name: cyclin-dependent kinase 1 phosphorylated form (human) def: "A cyclin-dependent kinase 1 phosphorylated form in human." [PRO:DAN] comment: Category=organism-modification. synonym: "hCDK1/PhosRes+" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027125 ! cyclin-dependent kinase 1 phosphorylated form [Term] id: PR:000027121 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 3 def: "A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14 and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291] comment: Category=modification. synonym: "CDK1/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx] is_a: PR:000026179 ! cyclin-dependent kinase 1 isoform 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000027122 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 4 def: "A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14, Tyr-15, and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074] comment: Category=modification. synonym: "CDK1/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx] is_a: PR:000026179 ! cyclin-dependent kinase 1 isoform 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine [Term] id: PR:000027123 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human) def: "A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291] comment: Category=organism-modification. synonym: "hCDK1/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "phospho-(Thr 14, Thr 161)Cdc2 (human)" EXACT [Reactome:R-HSA-170078, Reactome:R-HSA-170291] synonym: "UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-170078 "PR:000027123 located_in GO:0005654" xref: Reactome:R-HSA-170291 "PR:000027123 located_in GO:0005829" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000027121 ! cyclin-dependent kinase 1 isoform 1 phosphorylated 3 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000026179 name: cyclin-dependent kinase 1 isoform 1 def: "A cyclin-dependent kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06493-1 or a 1:1 ortholog thereof." [PRO:CNx] comment: Category=sequence. synonym: "CDK1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003271 ! cyclin-dependent kinase 1 [Term] id: PR:P06493 name: cyclin-dependent kinase 1 (human) def: "A cyclin-dependent kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06493] comment: Category=organism-gene. synonym: "CDC2" RELATED Gene-based [UniProtKB:P06493] synonym: "CDK1" RELATED Gene-based [UniProtKB:P06493] synonym: "CDKN1" RELATED Gene-based [UniProtKB:P06493] synonym: "hCDK1" EXACT PRO-short-label [PRO:DNx] synonym: "CDC28A" RELATED Gene-based [UniProtKB:P06493] synonym: "P34CDC2" RELATED Gene-based [UniProtKB:P06493] synonym: "p34 protein kinase (human)" EXACT [UniProtKB:P06493] synonym: "cell division protein kinase 1 (human)" EXACT [UniProtKB:P06493] synonym: "cell division control protein 2 homolog (human)" EXACT [UniProtKB:P06493] xref: Reactome:R-HSA-68889 "PR:P06493 located_in GO:0005654" xref: Reactome:R-HSA-264424 "PR:P06493 located_in GO:0005789" xref: Reactome:R-HSA-170075 "PR:P06493 located_in GO:0005829" xref: DTO:03100066 xref: UniProtKB:P06493 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003271 ! cyclin-dependent kinase 1 relationship: has_gene_template HGNC:1722 ! CDK1 (human) [Term] id: PR:P06493-2 name: cyclin-dependent kinase 1 isoform h2 (human) def: "A cyclin-dependent kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06493-2." [PRO:DNx, UniProtKB:P06493] comment: Category=organism-sequence. synonym: "hCDK1/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "cyclin-dependent kinase 1 isoform CDC2deltaT (human)" EXACT [UniProtKB:P06493] xref: UniProtKB:P06493-2 is_a: PR:P06493 ! cyclin-dependent kinase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P06493-1 name: cyclin-dependent kinase 1 isoform 1 (human) def: "A cyclin-dependent kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx] comment: Category=organism-sequence. Requested by=PubChem. synonym: "hCDK1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06493-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026179 ! cyclin-dependent kinase 1 isoform 1 [Term] id: PR:P13863 name: cyclin-dependent kinase 1 (chicken) def: "A cyclin-dependent kinase 1 that is encoded in the genome of chicken." [OMA:P13863, PRO:DAN] comment: Category=organism-gene. synonym: "CDC2" RELATED Gene-based [UniProtKB:P13863] synonym: "CDK1" RELATED Gene-based [UniProtKB:P13863] synonym: "chick-CDK1" EXACT PRO-short-label [PRO:DNx] synonym: "p34 protein kinase (chicken)" EXACT [UniProtKB:P13863] synonym: "cell division protein kinase 1 (chicken)" EXACT [UniProtKB:P13863] synonym: "cell division control protein 2 homolog (chicken)" EXACT [UniProtKB:P13863] xref: UniProtKB:P13863 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000003271 ! cyclin-dependent kinase 1 relationship: has_gene_template NCBIGene:396252 ! CDK1 (chicken) [Term] id: PR:P23572 name: cyclin-dependent kinase 1 (fruit fly) def: "A cyclin-dependent kinase 1 that is encoded in the genome of fruit fly." [OMA:P23572, PANTHER:PTHR24056:SF123, PRO:DNx] comment: Category=organism-gene. synonym: "Cdk1" RELATED Gene-based [UniProtKB:P23572] synonym: "cdc2" RELATED Gene-based [UniProtKB:P23572] synonym: "CG5363" RELATED Gene-based [UniProtKB:P23572] synonym: "fly-CDK1" EXACT PRO-short-label [PRO:DNx] synonym: "CDK1 (fruit fly)" EXACT [UniProtKB:P23572] synonym: "p34 protein kinase (fruit fly)" EXACT [UniProtKB:P23572] synonym: "cell division protein kinase 1 (fruit fly)" EXACT [UniProtKB:P23572] synonym: "cell division control protein 2 homolog (fruit fly)" EXACT [UniProtKB:P23572] xref: UniProtKB:P23572 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000003271 ! cyclin-dependent kinase 1 relationship: has_gene_template FlyBase:FBgn0004106 ! Cdk1 (fruit fly) [Term] id: PR:000026181 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (human) def: "A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNx, Reactome:R-HSA-170045, Reactome:R-HSA-170064] comment: Category=organism-modification. synonym: "hCDK1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "phospho-Cdc2 (Thr 14)" EXACT [] synonym: "UniProtKB:P06493-1, Thr-14, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-170045 "PR:000026181 located_in GO:0005654" xref: Reactome:R-HSA-170064 "PR:000026181 located_in GO:0005829" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026180 ! cyclin-dependent kinase 1 isoform 1 phosphorylated 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000026180 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 1 def: "A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated on a Thr residue within the N-terminal nucleotide binding region. This modification inactivates the kinase. Example: UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNx, Reactome:R-HSA-170045, Reactome:R-HSA-170064] comment: Category=modification. synonym: "CDK1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "phospho-Cdc2 (Thr 14)" RELATED [Reactome:R-HSA-170045, Reactome:R-HSA-170064] is_a: PR:000026179 ! cyclin-dependent kinase 1 isoform 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000026182 name: cyclin-dependent kinase 1 isoform 1 phosphorylated 2 def: "A cyclin-dependent kinase 1 isoform 1 that has been post-translationally modified to include a phosphorylated Thr residue at the position equivalent to Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx] comment: Category=modification. synonym: "CDK1/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000026179 ! cyclin-dependent kinase 1 isoform 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:P11440-1 name: cyclin-dependent kinase 1 isoform 1 (mouse) def: "A cyclin-dependent kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx] comment: Category=organism-sequence. synonym: "mCDK1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P11440-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000026179 ! cyclin-dependent kinase 1 isoform 1 [Term] id: PR:P11440 name: cyclin-dependent kinase 1 (mouse) def: "A cyclin-dependent kinase 1 that is encoded in the genome of mouse." [OMA:P11440, PRO:DNx] comment: Category=organism-gene. synonym: "Cdc2" RELATED Gene-based [UniProtKB:P11440] synonym: "Cdk1" RELATED Gene-based [UniProtKB:P11440] synonym: "Cdc2a" RELATED Gene-based [UniProtKB:P11440] synonym: "Cdkn1" RELATED Gene-based [UniProtKB:P11440] synonym: "mCDK1" EXACT PRO-short-label [PRO:DNx] synonym: "CDK1 (mouse)" EXACT [UniProtKB:P11440] synonym: "p34 protein kinase (mouse)" EXACT [UniProtKB:P11440] synonym: "cell division protein kinase 1 (mouse)" EXACT [UniProtKB:P11440] synonym: "cell division control protein 2 homolog (mouse)" EXACT [UniProtKB:P11440] xref: UniProtKB:P11440 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003271 ! cyclin-dependent kinase 1 relationship: has_gene_template MGI:88351 ! Cdk1 (mouse)