[Term]
id: PR:Q9QZR9
name: collagen alpha-4(IV) chain (mouse)
def: "A collagen alpha-4(IV) chain that is encoded in the genome of mouse." [OMA:Q9QZR9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Col4a4" RELATED Gene-based [UniProtKB:Q9QZR9]
synonym: "mCOL4A4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QZR9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003337 ! collagen alpha-4(IV) chain
relationship: has_gene_template MGI:104687 ! Col4a4 (mouse)

[Term]
id: PR:P53420
name: collagen alpha-4(IV) chain (human)
def: "A collagen alpha-4(IV) chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P53420]
comment: Category=organism-gene.
synonym: "COL4A4" RELATED Gene-based [UniProtKB:P53420]
synonym: "hCOL4A4" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-4088273 "PR:P53420 located_in GO:0005576"
xref: UniProtKB:P53420
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003337 ! collagen alpha-4(IV) chain
relationship: has_gene_template HGNC:2206 ! COL4A4 (human)

[Term]
id: PR:P53420-1
name: collagen alpha-4(IV) chain isoform 1 (human)
def: "A collagen alpha-4(IV) chain isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOL4A4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53420-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003338 ! collagen alpha-4(IV) chain isoform 1

[Term]
id: PR:000003340
name: collagen alpha-4(IV) chain isoform 1, signal peptide removed form
def: "A collagen alpha-4(IV) chain isoform 1 that has had the signal peptide removed to yield the mature protein. Example: UniProtKB:P53420-1, 39-1690." [PRO:CNA]
comment: Category=modification.
synonym: "COL4A4/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "collagen alpha-4(IV) chain" BROAD [PRO:DNx]
synonym: "collagen alpha-4(IV) chain mature" EXACT []
synonym: "collagen alpha-4(IV) chain isoform 1 cleaved 1" EXACT []
intersection_of: PR:000003338 ! collagen alpha-4(IV) chain isoform 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000046915
name: collagen alpha-4(IV) chain, signal peptide removed 5-hydroxy-lysine and 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:P53420, 39-1690, MOD:00037|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022976, Reactome:R-HSA-2127423]
comment: Category=organism-modification.
synonym: "hCOL4A4/SigPep-/5hL4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005850, MOD:00037|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P53420, 39-1690, MOD:00037|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022976 "PR:000046915 located_in GO:0005788"
xref: Reactome:R-HSA-2127423 "PR:000046915 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9QZR9-1
name: collagen alpha-4(IV) chain isoform m1 (mouse)
def: "A collagen alpha-4(IV) chain (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZR9-1." [PRO:DNx, UniProtKB:Q9QZR9]
comment: Category=organism-sequence.
synonym: "mCOL4A4/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QZR9-1
is_a: PR:Q9QZR9 ! collagen alpha-4(IV) chain (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QZR9-2
name: collagen alpha-4(IV) chain isoform m2 (mouse)
def: "A collagen alpha-4(IV) chain (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZR9-2." [PRO:DNx, UniProtKB:Q9QZR9]
comment: Category=organism-sequence.
synonym: "mCOL4A4/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QZR9-2
is_a: PR:Q9QZR9 ! collagen alpha-4(IV) chain (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000025424
name: collagen alpha-4(IV) chain proteolytic cleavage product
def: "A collagen alpha-4(IV) chain that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "COL4A4/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000003337 ! collagen alpha-4(IV) chain

[Term]
id: PR:000003337
name: collagen alpha-4(IV) chain
def: "A collagen type IV alpha chain that is a translation product of the human COL4A4 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "COL4A4" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003388 ! collagen type IV alpha chain

[Term]
id: PR:000046914
name: collagen alpha-4(IV) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P53420, 39-1690, MOD:00037|MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022963, Reactome:R-HSA-2127341]
comment: Category=organism-modification.
synonym: "hCOL4A4/SigPep-/5hL3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005850, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P53420, 39-1690, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022963 "PR:000046914 located_in GO:0005788"
xref: Reactome:R-HSA-2127341 "PR:000046914 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046909
name: collagen alpha-4(IV) chain 5-hydroxy-lysine and 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:P53420, MOD:00037|MOD:00039." [PRO:DNx, Reactome:R-HSA-4088217]
comment: Category=organism-modification.
synonym: "hCOL4A4/5hL4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53420, MOD:00037|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4088217 "PR:000046909 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046908
name: collagen alpha-4(IV) chain 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P53420, MOD:00037|MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-4088215]
comment: Category=organism-modification.
synonym: "hCOL4A4/5hL3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53420, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4088215 "PR:000046908 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046907
name: collagen alpha-4(IV) chain 5-hydroxy-lysine form (human)
def: "A collagen alpha-4(IV) chain (human) that includes at least one 5-hydroxy-lysine. UniProtKB:P53420, MOD:00037." [PRO:DNx, Reactome:R-HSA-4088232]
comment: Category=organism-modification.
synonym: "hCOL4A4/5HyLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53420, MOD:00037" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4088232 "PR:000046907 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046906
name: collagen alpha-4(IV) chain 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that includes at least one 4-hydroxy-proline. UniProtKB:P53420, MOD:00039." [PRO:DNx, Reactome:R-HSA-4088242]
comment: Category=organism-modification.
synonym: "hCOL4A4/4HyPro+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53420, MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4088242 "PR:000046906 located_in GO:0005576"
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046905
name: collagen alpha-4(IV) chain 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that includes at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P53420, MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-4088234]
comment: Category=organism-modification.
synonym: "hCOL4A4/3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53420, MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4088234 "PR:000046905 located_in GO:0005576"
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046913
name: collagen alpha-4(IV) chain, signal peptide removed 5-hydroxy-lysine form (human)
def: "A collagen alpha-4(IV) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine. UniProtKB:P53420, 39-1690, MOD:00037." [PRO:DNx, Reactome:R-HSA-2022419, Reactome:R-HSA-2127415]
comment: Category=organism-modification.
synonym: "hCOL4A4/SigPep-/5HyLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005850, MOD:00037" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P53420, 39-1690, MOD:00037" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022419 "PR:000046913 located_in GO:0005788"
xref: Reactome:R-HSA-2127415 "PR:000046913 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046910
name: collagen alpha-4(IV) chain, signal peptide removed form (human)
def: "A collagen alpha-4(IV) chain (human) that has had the signal peptide removed. UniProtKB:P53420, 39-1690." [PRO:DNx, Reactome:R-HSA-1980248, Reactome:R-HSA-2127405]
comment: Category=organism-modification.
synonym: "PRO_0000005850" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCOL4A4/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53420, 39-1690" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1980248 "PR:000046910 located_in GO:0005788"
xref: Reactome:R-HSA-2127405 "PR:000046910 located_in GO:0005576"
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046911
name: collagen alpha-4(IV) chain, signal peptide removed 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that has had the signal peptide removed and that includes at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P53420, 39-1690, MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022521, Reactome:R-HSA-2127394]
comment: Category=organism-modification.
synonym: "hCOL4A4/SigPep-/3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005850, MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P53420, 39-1690, MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022521 "PR:000046911 located_in GO:0005788"
xref: Reactome:R-HSA-2127394 "PR:000046911 located_in GO:0005576"
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046912
name: collagen alpha-4(IV) chain, signal peptide removed 4-hydroxy-proline form (human)
def: "A collagen alpha-4(IV) chain (human) that has had the signal peptide removed and that includes at least one 4-hydroxy-proline. UniProtKB:P53420, 39-1690, MOD:00039." [PRO:DNx, Reactome:R-HSA-2022129, Reactome:R-HSA-2127400]
comment: Category=organism-modification.
synonym: "hCOL4A4/SigPep-/4HyPro+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005850, MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P53420, 39-1690, MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022129 "PR:000046912 located_in GO:0005788"
xref: Reactome:R-HSA-2127400 "PR:000046912 located_in GO:0005576"
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P53420 ! collagen alpha-4(IV) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000003338
name: collagen alpha-4(IV) chain isoform 1
def: "A collagen alpha-4(IV) chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53420-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "COL4A4/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003337 ! collagen alpha-4(IV) chain