[Term]
id: PR:000003353
name: collagen alpha-1(VI) chain
def: "A collagen type VI alpha chain that is a translation product of the human COL6A1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "COL6A1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003386 ! collagen type VI alpha chain

[Term]
id: PR:000046961
name: collagen alpha-1(VI) chain, signal peptide removed form (human)
def: "A collagen alpha-1(VI) chain (human) that has had the signal peptide removed. UniProtKB:P12109, 20-1028." [PRO:DNx, Reactome:R-HSA-1614453, Reactome:R-HSA-2127512]
comment: Category=organism-modification.
synonym: "PRO_0000005758" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCOL6A1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12109, 20-1028" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2127512 "PR:000046961 located_in GO:0005576"
xref: Reactome:R-HSA-1614453 "PR:000046961 located_in GO:0005788"
intersection_of: PR:P12109 ! collagen alpha-1(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046963
name: collagen alpha-1(VI) chain, signal peptide removed 4-hydroxy-proline form (human)
def: "A collagen alpha-1(VI) chain (human) that has had the signal peptide removed and that includes at least one 4-hydroxy-proline. UniProtKB:P12109, 20-1028, MOD:00039." [PRO:DNx, Reactome:R-HSA-2022508, Reactome:R-HSA-2127464]
comment: Category=organism-modification.
synonym: "hCOL6A1/SigPep-/4HyPro+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005758, MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12109, 20-1028, MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022508 "PR:000046963 located_in GO:0005788"
xref: Reactome:R-HSA-2127464 "PR:000046963 located_in GO:0005576"
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12109 ! collagen alpha-1(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046962
name: collagen alpha-1(VI) chain, signal peptide removed 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-1(VI) chain (human) that has had the signal peptide removed and that includes at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P12109, 20-1028, MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022507, Reactome:R-HSA-2127484]
comment: Category=organism-modification.
synonym: "hCOL6A1/SigPep-/3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005758, MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12109, 20-1028, MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022507 "PR:000046962 located_in GO:0005788"
xref: Reactome:R-HSA-2127484 "PR:000046962 located_in GO:0005576"
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12109 ! collagen alpha-1(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046965
name: collagen alpha-1(VI) chain, signal peptide removed 5-hydroxy-lysine, 3-hydroxy-proline and 4-hydroxy-proline form (human)
def: "A collagen alpha-1(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine, at least one 3-hydroxy-proline and at least one 4-hydroxy-proline. UniProtKB:P12109, 20-1028, MOD:00037|MOD:00038|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022944, Reactome:R-HSA-2127527]
comment: Category=organism-modification.
synonym: "hCOL6A1/SigPep-/5hL3hP4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005758, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12109, 20-1028, MOD:00037|MOD:00038|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022944 "PR:000046965 located_in GO:0005788"
xref: Reactome:R-HSA-2127527 "PR:000046965 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00038 ! 3-hydroxy-L-proline
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12109 ! collagen alpha-1(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046964
name: collagen alpha-1(VI) chain, signal peptide removed 5-hydroxy-lysine form (human)
def: "A collagen alpha-1(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine. UniProtKB:P12109, 20-1028, MOD:00037." [PRO:DNx, Reactome:R-HSA-2022997, Reactome:R-HSA-2127519]
comment: Category=organism-modification.
synonym: "hCOL6A1/SigPep-/5HyLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005758, MOD:00037" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12109, 20-1028, MOD:00037" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022997 "PR:000046964 located_in GO:0005788"
xref: Reactome:R-HSA-2127519 "PR:000046964 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: PR:P12109 ! collagen alpha-1(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12109
name: collagen alpha-1(VI) chain (human)
def: "A collagen alpha-1(VI) chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12109]
comment: Category=organism-gene.
synonym: "COL6A1" RELATED Gene-based [UniProtKB:P12109]
synonym: "hCOL6A1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12109
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003353 ! collagen alpha-1(VI) chain
relationship: has_gene_template HGNC:2211 ! COL6A1 (human)

[Term]
id: PR:000046966
name: collagen alpha-1(VI) chain, signal peptide removed 5-hydroxy-lysine and 4-hydroxy-proline form (human)
def: "A collagen alpha-1(VI) chain (human) that has had the signal peptide removed and that includes at least one 5-hydroxy-lysine and at least one 4-hydroxy-proline. UniProtKB:P12109, 20-1028, MOD:00037|MOD:00039." [PRO:DNx, Reactome:R-HSA-2022965, Reactome:R-HSA-2127506]
comment: Category=organism-modification.
synonym: "hCOL6A1/SigPep-/5hL4hP+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000005758, MOD:00037|MOD:00039" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P12109, 20-1028, MOD:00037|MOD:00039" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022965 "PR:000046966 located_in GO:0005788"
xref: Reactome:R-HSA-2127506 "PR:000046966 located_in GO:0005576"
intersection_of: has_part MOD:00037 ! 5-hydroxy-L-lysine
intersection_of: has_part MOD:00039 ! 4-hydroxy-L-proline
intersection_of: PR:P12109 ! collagen alpha-1(VI) chain (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12109-1
name: collagen alpha-1(VI) chain isoform 1 (human)
def: "A collagen alpha-1(VI) chain isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCOL6A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P12109-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003354 ! collagen alpha-1(VI) chain isoform 1

[Term]
id: PR:000054956
name: collagen alpha-1(VI) chain O-glycosylated 2 (human)
def: "A collagen alpha-1(VI) chain (human) that has been O-glycosylated at the residue equivalent to Thr-703 of the amino acid sequence represented by UniProtKB:P12109-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P12109-1, Thr-703, MOD:00005~GNO:G43417UB." [GlyGen:P12109-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCOL6A1/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12109-1, Thr-703, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P12109 ! collagen alpha-1(VI) chain (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054955
name: collagen alpha-1(VI) chain O-glycosylated 1 (human)
def: "A collagen alpha-1(VI) chain (human) that has been O-glycosylated at the residue equivalent to Thr-701 of the amino acid sequence represented by UniProtKB:P12109-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P12109-1, Thr-701, MOD:00005~GNO:G43417UB." [GlyGen:P12109-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCOL6A1/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P12109-1, Thr-701, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P12109 ! collagen alpha-1(VI) chain (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens