[Term]
id: PR:P49588-2
name: alanine--tRNA ligase, cytoplasmic isoform h2 (human)
def: "An alanine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49588-2." [PRO:DNx, UniProtKB:P49588]
comment: Category=organism-sequence.
synonym: "hAARS1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49588-2
is_a: PR:P49588 ! alanine--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40825-2
name: alanine--tRNA ligase, mitochondrial isoform Cytoplasmic (yeast)
def: "An alanine--tRNA ligase, mitochondrial (yeast) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40825-2." [PRO:DNx, UniProtKB:P40825]
comment: Category=organism-sequence.
synonym: "yAARS/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40825-2
is_a: PR:P40825 ! alanine--tRNA ligase, mitochondrial (yeast)
relationship: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C

[Term]
id: PR:P40825-1
name: alanine--tRNA ligase, mitochondrial isoform Mitochondrial (yeast)
def: "An alanine--tRNA ligase, mitochondrial (yeast) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40825-1." [PRO:DNx, UniProtKB:P40825]
comment: Category=organism-sequence.
synonym: "yAARS/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40825-1
is_a: PR:P40825 ! alanine--tRNA ligase, mitochondrial (yeast)
relationship: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C

[Term]
id: PR:Q5A8K2
name: alanine--tRNA ligase (Candida albicans SC5314)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of Candida albicans SC5314." [OMA:Q5A8K2, PRO:DNx]
comment: Category=organism-gene. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DNx.
synonym: "ALA1" RELATED Gene-based [UniProtKB:Q5A8K2]
synonym: "SYA1" RELATED Gene-based [UniProtKB:Q5A8K2]
synonym: "CaO19.5746" RELATED Gene-based [UniProtKB:Q5A8K2]
synonym: "Calb-AARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "CaO19.13169" RELATED Gene-based [UniProtKB:Q5A8K2]
synonym: "CAALFM_C603720WA" RELATED Gene-based [UniProtKB:Q5A8K2]
synonym: "AlaRS (Candida albicans SC5314)" EXACT [UniProtKB:Q5A8K2]
synonym: "alanyl-tRNA synthetase (Candida albicans SC5314)" EXACT [UniProtKB:Q5A8K2]
xref: UniProtKB:Q5A8K2
intersection_of: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template NCBIGene:3640285 ! ALA1 (Candida albicans SC5314)

[Term]
id: PR:Q9VLM8
name: alanine--tRNA ligase, cytoplasmic (fruit fly)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of fruit fly." [OMA:Q9VLM8, PRO:DNx]
comment: Category=organism-gene.
synonym: "alaS" RELATED Gene-based [UniProtKB:Q9VLM8]
synonym: "AlaRS" RELATED Gene-based [UniProtKB:Q9VLM8]
synonym: "CG13391" RELATED Gene-based [UniProtKB:Q9VLM8]
synonym: "Aats-ala" RELATED Gene-based [UniProtKB:Q9VLM8]
synonym: "fly-AARS" EXACT PRO-short-label [PRO:DNx]
synonym: "AlaRS (fruit fly)" BROAD [PRO:DAN]
synonym: "alanine--tRNA ligase (fruit fly)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (fruit fly)" BROAD [PRO:DAN, UniProtKB:Q9VLM8]
synonym: "alanyl-tRNA synthetase, cytoplasmic (fruit fly)" EXACT [PRO:DAN]
xref: UniProtKB:Q9VLM8
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template FlyBase:FBgn0027094 ! AlaRS (Drosophila melanogaster)

[Term]
id: PR:000050487
name: alanine--tRNA ligase, cytoplasmic isoform 1 unmethylated 1 (mouse)
def: "An alanine--tRNA ligase, cytoplasmic isoform 1 (mouse) that lacks methylation at the position equivalent to Lys-943 of the amino acid sequence represented by UniProtKB:Q8BGQ7-1. UniProtKB:Q8BGQ7-1, Lys-943, PR:000026291." [PMID:32611769, PRO:HJD, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:32611769).
synonym: "mAARS1/iso:1/UnMe:1" EXACT PRO-short-label [PRO:KER]
synonym: "UniProtKB:Q8BGQ7-1, Lys-943, PR:000026291" EXACT PRO-proteoform-std [PRO:KER]
is_a: PR:Q8BGQ7-1 ! alanine--tRNA ligase, cytoplasmic isoform 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000050486
name: alanine--tRNA ligase, cytoplasmic isoform 1 methylated 1 (mouse)
def: "An alanine--tRNA ligase, cytoplasmic isoform 1 (mouse) that has been methylated at the position equivalent to Lys-943 of the amino acid sequence represented by UniProtKB:Q8BGQ7-1. UniProtKB:Q8BGQ7-1, Lys-943, MOD:00663." [PMID:32611769, PRO:HJD, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:32611769). Methylase=("Mettl21c"; PR:Q8BLU2; Lys-943).
synonym: "mAARS1/iso:1/Me:1" EXACT PRO-short-label [PRO:KER]
synonym: "UniProtKB:Q8BGQ7-1, Lys-943, MOD:00663" NARROW PRO-proteoform-std [PRO:KER]
is_a: PR:Q8BGQ7-1 ! alanine--tRNA ligase, cytoplasmic isoform 1 (mouse)
relationship: has_part MOD:00663 ! methylated lysine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000003529
name: alanine--tRNA ligase, cytoplasmic
def: "A protein that is a translation product of the human AARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AARS" RELATED Gene-based []
synonym: "AARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "AlaRS" BROAD [PRO:DAN]
synonym: "alanine--tRNA ligase" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase" BROAD [PRO:DAN]
synonym: "renal carcinoma antigen NY-REN-42" EXACT []
synonym: "alanyl-tRNA synthetase, cytoplasmic" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O13914
name: alanine--tRNA ligase (Schizosaccharomyces pombe 972h-)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O13914, PRO:DNx]
comment: Category=organism-gene.
synonym: "ala1" RELATED Gene-based [UniProtKB:O13914]
synonym: "ars1" RELATED Gene-based [UniProtKB:O13914]
synonym: "SPAC23C11.09" RELATED Gene-based [UniProtKB:O13914]
synonym: "Spom972h-AARS" EXACT PRO-short-label [PRO:DNx]
synonym: "AlaRS (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:O13914]
synonym: "alanyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:O13914]
xref: UniProtKB:O13914
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template PomBase:SPAC23C11.09 ! ala1 (Schizosaccharomyces pombe)

[Term]
id: PR:P49588-1
name: alanine--tRNA ligase, cytoplasmic isoform 1 (human)
def: "An alanine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49588-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039590 ! alanine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:P49588
name: alanine--tRNA ligase, cytoplasmic (human)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49588]
comment: Category=organism-gene.
synonym: "AARS" RELATED Gene-based [UniProtKB:P49588]
synonym: "AARS1" RELATED Gene-based [UniProtKB:P49588]
synonym: "hAARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "AlaRS (human)" BROAD [PRO:DAN]
synonym: "alanine--tRNA ligase (human)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (human)" BROAD [PRO:DAN]
synonym: "renal carcinoma antigen NY-REN-42 (human)" EXACT [UniProtKB:P49588]
synonym: "alanyl-tRNA synthetase, cytoplasmic (human)" EXACT [PRO:DAN]
xref: Reactome:R-HSA-379666 "PR:P49588 located_in GO:0005829"
xref: UniProtKB:P49588
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template HGNC:20 ! AARS1 (human)

[Term]
id: PR:O01541
name: alanine--tRNA ligase, cytoplasmic (worm)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of worm." [OMA:O01541, PRO:DNx]
comment: Category=organism-gene.
synonym: "ars-2" RELATED Gene-based [UniProtKB:O01541]
synonym: "aars-2" RELATED Gene-based [UniProtKB:O01541]
synonym: "F28H1.3" RELATED Gene-based [UniProtKB:O01541]
synonym: "AARS (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "AlaRS (worm)" BROAD [PRO:DAN]
synonym: "AlaRS A (worm)" EXACT [UniProtKB:O01541]
synonym: "alanine--tRNA ligase (worm)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (worm)" BROAD [PRO:DAN, UniProtKB:O01541]
synonym: "alanyl-tRNA synthetase, cytoplasmic (worm)" EXACT [PRO:DAN]
xref: UniProtKB:O01541
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template WormBase:WBGene00000197 ! aars-2 (worm)

[Term]
id: PR:P36428
name: alanine--tRNA ligase (Arabidopsis thaliana)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of Arabidopsis thaliana." [OMA:P36428, PRO:DNx]
comment: Category=organism-gene.
synonym: "ALARS" RELATED Gene-based [UniProtKB:P36428]
synonym: "ALATS" RELATED Gene-based [UniProtKB:P36428]
synonym: "At-AARS" EXACT PRO-short-label [PRO:DNx]
synonym: "F14I3.17" RELATED Gene-based [UniProtKB:P36428]
synonym: "At1g50200" RELATED Gene-based [UniProtKB:P36428]
synonym: "AlaRS (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:P36428]
synonym: "alanyl-tRNA synthetase (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:P36428]
xref: UniProtKB:P36428
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template Araport:AT1G50200 ! ALATS (Arabidopsis thaliana)

[Term]
id: PR:P40825
name: alanine--tRNA ligase, mitochondrial (yeast)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of yeast." [OMA:P40825, PRO:DNx]
comment: Category=organism-gene.
synonym: "ALA1" RELATED Gene-based [UniProtKB:P40825]
synonym: "CDC64" RELATED Gene-based [UniProtKB:P40825]
synonym: "yAARS" EXACT PRO-short-label [PRO:DNx]
synonym: "YOR335C" RELATED Gene-based [UniProtKB:P40825]
synonym: "AlaRS (yeast)" BROAD [PRO:DAN, UniProtKB:P40825]
synonym: "alanine--tRNA ligase (yeast)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (yeast)" BROAD [PRO:DAN, UniProtKB:P40825]
synonym: "alanyl-tRNA synthetase, mitochondrial (yeast)" EXACT [PRO:DAN]
xref: UniProtKB:P40825
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template SGD:S000005862 ! ALA1 (yeast)

[Term]
id: PR:Q8BGQ7-1
name: alanine--tRNA ligase, cytoplasmic isoform 1 (mouse)
def: "An alanine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mAARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8BGQ7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039590 ! alanine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:Q54Y20
name: alanine--tRNA ligase, cytoplasmic (Dictyostelium discoideum)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54Y20, PRO:DNx]
comment: Category=organism-gene.
synonym: "alaS" RELATED Gene-based [UniProtKB:Q54Y20]
synonym: "Dicty-AARS" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0277823" RELATED Gene-based [UniProtKB:Q54Y20]
synonym: "AlaRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54Y20]
synonym: "alanine--tRNA ligase (Dictyostelium discoideum)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54Y20]
synonym: "alanyl-tRNA synthetase, cytoplasmic (Dictyostelium discoideum)" EXACT [PRO:DAN]
xref: UniProtKB:Q54Y20
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template dictyBase:DDB_G0277823 ! alaS (Dictyostelium discoideum)

[Term]
id: PR:000039590
name: alanine--tRNA ligase, cytoplasmic isoform 1
def: "An alanine--tRNA ligase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49588-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "AARS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003529 ! alanine--tRNA ligase, cytoplasmic

[Term]
id: PR:P36428-2
name: alanine--tRNA ligase isoform Cytoplasmic (Arabidopsis thaliana)
def: "An alanine--tRNA ligase (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36428-2." [PRO:DNx, UniProtKB:P36428]
comment: Category=organism-sequence.
synonym: "At-AARS/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36428-2
is_a: PR:P36428 ! alanine--tRNA ligase (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:P36428-1
name: alanine--tRNA ligase isoform Mitochondrial (Arabidopsis thaliana)
def: "An alanine--tRNA ligase (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36428-1." [PRO:DNx, UniProtKB:P36428]
comment: Category=organism-sequence.
synonym: "At-AARS/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36428-1
is_a: PR:P36428 ! alanine--tRNA ligase (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:Q8BGQ7
name: alanine--tRNA ligase, cytoplasmic (mouse)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q8BGQ7, PRO:DAN]
comment: Category=organism-gene.
synonym: "Aars" RELATED Gene-based [UniProtKB:Q8BGQ7]
synonym: "Aars1" RELATED Gene-based [UniProtKB:Q8BGQ7]
synonym: "mAARS" EXACT PRO-short-label [PRO:DAN]
synonym: "Sti (mouse)" EXACT [UniProtKB:Q8BGQ7]
synonym: "AlaRS (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BGQ7]
synonym: "protein sticky (mouse)" EXACT [UniProtKB:Q8BGQ7]
synonym: "alanine--tRNA ligase (mouse)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (mouse)" BROAD [PRO:DAN, UniProtKB:Q8BGQ7]
synonym: "alanyl-tRNA synthetase, cytoplasmic (mouse)" EXACT [PRO:DAN]
xref: UniProtKB:Q8BGQ7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template MGI:2384560 ! Aars (mouse)

[Term]
id: PR:Q5A8K2-2
name: alanine--tRNA ligase isoform Cytoplasmic (Candida albicans SC5314)
def: "An alanine--tRNA ligase (Candida albicans SC5314) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5A8K2-2." [PRO:DNx, UniProtKB:Q5A8K2]
comment: Category=organism-sequence.
synonym: "Calb-AARS1/iso:Cytoplasmic" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5A8K2-2
is_a: PR:Q5A8K2 ! alanine--tRNA ligase (Candida albicans SC5314)
relationship: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314

[Term]
id: PR:Q5A8K2-1
name: alanine--tRNA ligase isoform Mitochondrial (Candida albicans SC5314)
def: "An alanine--tRNA ligase (Candida albicans SC5314) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5A8K2-1." [PRO:DNx, UniProtKB:Q5A8K2]
comment: Category=organism-sequence.
synonym: "Calb-AARS1/iso:Mitochondrial" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5A8K2-1
is_a: PR:Q5A8K2 ! alanine--tRNA ligase (Candida albicans SC5314)
relationship: only_in_taxon NCBITaxon:237561 ! Candida albicans SC5314

[Term]
id: PR:P50475
name: alanine--tRNA ligase, cytoplasmic (rat)
def: "An alanine--tRNA ligase, cytoplasmic that is encoded in the genome of rat." [OMA:P50475, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aars" RELATED Gene-based [UniProtKB:P50475]
synonym: "Aars1" RELATED Gene-based [UniProtKB:P50475]
synonym: "rAARS" EXACT PRO-short-label [PRO:DNx]
synonym: "AlaRS (rat)" BROAD [PRO:DAN, UniProtKB:P50475]
synonym: "alanine--tRNA ligase (rat)" BROAD [PRO:DAN]
synonym: "alanyl-tRNA synthetase (rat)" BROAD [PRO:DAN, UniProtKB:P50475]
synonym: "alanyl-tRNA synthetase, cytoplasmic (rat)" EXACT [PRO:DAN]
xref: UniProtKB:P50475
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003529 ! alanine--tRNA ligase, cytoplasmic
relationship: has_gene_template RGD:1304832 ! Aars (rat)