[Term]
id: PR:000039731
name: ATP-citrate synthase isoform 2
def: "An ATP-citrate synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53396-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "ACLY/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003628 ! ATP-citrate synthase

[Term]
id: PR:P53396
name: ATP-citrate synthase (human)
def: "An ATP-citrate synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P53396]
comment: Category=organism-gene.
synonym: "ACLY" RELATED Gene-based [UniProtKB:P53396]
synonym: "hACLY" EXACT PRO-short-label [PRO:DNx]
synonym: "ACL (human)" EXACT [UniProtKB:P53396]
synonym: "citrate cleavage enzyme (human)" EXACT [UniProtKB:P53396]
synonym: "ATP-citrate (pro-S-)-lyase (human)" EXACT [UniProtKB:P53396]
xref: Reactome:R-HSA-76187 "PR:P53396 located_in GO:0005829"
xref: Reactome:R-HSA-6806218 "PR:P53396 located_in GO:0005576"
xref: Reactome:R-HSA-6798765 "PR:P53396 located_in GO:0035578"
xref: Reactome:R-HSA-6801031 "PR:P53396 located_in GO:1904813"
xref: UniProtKB:P53396
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003628 ! ATP-citrate synthase
relationship: has_gene_template HGNC:115 ! ACLY (human)

[Term]
id: PR:Q91V92
name: ATP-citrate synthase (mouse)
def: "An ATP-citrate synthase that is encoded in the genome of mouse." [OMA:Q91V92, PRO:DNx]
comment: Category=organism-gene.
synonym: "Acly" RELATED Gene-based [UniProtKB:Q91V92]
synonym: "mACLY" EXACT PRO-short-label [PRO:DNx]
synonym: "citrate cleavage enzyme (mouse)" EXACT [UniProtKB:Q91V92]
synonym: "ATP-citrate (pro-S-)-lyase (mouse)" EXACT [UniProtKB:Q91V92]
xref: UniProtKB:Q91V92
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003628 ! ATP-citrate synthase
relationship: has_gene_template MGI:103251 ! Acly (mouse)

[Term]
id: PR:P53396-2
name: ATP-citrate synthase isoform 2 (human)
def: "An ATP-citrate synthase isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hACLY/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53396-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039731 ! ATP-citrate synthase isoform 2

[Term]
id: PR:000003628
name: ATP-citrate synthase
def: "A protein that is a translation product of the human ACLY gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ACLY" EXACT PRO-short-label [PRO:DNx]
synonym: "citrate cleavage enzyme" EXACT []
synonym: "ATP-citrate (pro-S-)-lyase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P53396-1
name: ATP-citrate synthase isoform h1 (human)
def: "An ATP-citrate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53396-1." [PRO:DNx, UniProtKB:P53396]
comment: Category=organism-sequence.
synonym: "hACLY/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53396-1
is_a: PR:P53396 ! ATP-citrate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16638-1
name: ATP-citrate synthase isoform r1 (rat)
def: "An ATP-citrate synthase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16638-1." [PRO:DNx, UniProtKB:P16638]
comment: Category=organism-sequence.
synonym: "rACLY/iso:r1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16638-1
is_a: PR:P16638 ! ATP-citrate synthase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P16638-2
name: ATP-citrate synthase isoform r2 (rat)
def: "An ATP-citrate synthase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16638-2." [PRO:DNx, UniProtKB:P16638]
comment: Category=organism-sequence.
synonym: "rACLY/iso:r2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P16638-2
is_a: PR:P16638 ! ATP-citrate synthase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P16638
name: ATP-citrate synthase (rat)
def: "An ATP-citrate synthase that is encoded in the genome of rat." [PANTHER:PTHR23118:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Acly" RELATED Gene-based [UniProtKB:P16638]
synonym: "rACLY" EXACT PRO-short-label [PRO:DNx]
synonym: "citrate cleavage enzyme (rat)" EXACT [UniProtKB:P16638]
synonym: "ATP-citrate (pro-S-)-lyase (rat)" EXACT [UniProtKB:P16638]
xref: UniProtKB:P16638
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003628 ! ATP-citrate synthase
relationship: has_gene_template RGD:2018 ! Acly (rat)

[Term]
id: PR:Q54YA2
name: uncharacterized protein, DDB_G0278341 translation product (Dictyostelium discoideum)
def: "An ATP-citrate synthase that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR23118:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-ACLY" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54YA2
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000003628 ! ATP-citrate synthase
relationship: has_gene_template dictyBase:DDB_G0278341 ! DDB_G0278341 (Dictyostelium discoideum)

[Term]
id: PR:Q91V92-1
name: ATP-citrate synthase isoform 1 (mouse)
def: "An ATP-citrate synthase isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mACLY/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q91V92-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039731 ! ATP-citrate synthase isoform 2

[Term]
id: PR:P53396-3
name: ATP-citrate synthase isoform h3 (human)
def: "An ATP-citrate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53396-3." [PRO:DNx, UniProtKB:P53396]
comment: Category=organism-sequence.
synonym: "hACLY/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P53396-3
is_a: PR:P53396 ! ATP-citrate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P53585
name: probable ATP-citrate synthase (worm)
def: "An ATP-citrate synthase that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "acly-1" RELATED Gene-based [UniProtKB:P53585]
synonym: "D1005.1" RELATED Gene-based [UniProtKB:P53585]
synonym: "ACLY (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "citrate cleavage enzyme (worm)" EXACT [UniProtKB:P53585]
synonym: "ATP-citrate (pro-S-)-lyase (worm)" EXACT [UniProtKB:P53585]
xref: UniProtKB:P53585
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000003628 ! ATP-citrate synthase
relationship: has_gene_template WormBase:WBGene00016995 ! D1005.1 (worm)