[Term] id: PR:O75173 name: a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) def: "An a disintegrin and metalloproteinase with thrombospondin motifs 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75173] comment: Category=organism-gene. synonym: "ADAMTS4" RELATED Gene-based [UniProtKB:O75173] synonym: "KIAA0688" RELATED Gene-based [UniProtKB:O75173] synonym: "hADAMTS4" EXACT PRO-short-label [PRO:DNx] synonym: "ADMP-1 (human)" EXACT [UniProtKB:O75173] synonym: "UNQ769/PRO1563" RELATED Gene-based [UniProtKB:O75173] synonym: "ADAM-TS4 (human)" EXACT [UniProtKB:O75173] synonym: "ADAMTS-4 (human)" EXACT [UniProtKB:O75173] synonym: "ADAM-TS 4 (human)" EXACT [UniProtKB:O75173] synonym: "aggrecanase-1 (human)" EXACT [UniProtKB:O75173] xref: UniProtKB:O75173 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003733 ! a disintegrin and metalloproteinase with thrombospondin motifs 4 relationship: has_gene_template HGNC:220 ! ADAMTS4 (human) [Term] id: PR:000050824 name: a disintegrin and metalloproteinase with thrombospondin motifs 4 O-glycosylated 2 (human) def: "An a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) that has been O-glycosylated at the residue equivalent to Thr-813 of the amino acid sequence represented by UniProtKB:O75173-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O75173-1, Thr-813, MOD:00005~GNO:G43417UB." [GlyGen:O75173-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hADAMTS4/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O75173-1, Thr-813, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O75173 ! a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050823 name: a disintegrin and metalloproteinase with thrombospondin motifs 4 O-glycosylated 1 (human) def: "An a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) that has been O-glycosylated at the residue equivalent to Thr-813 of the amino acid sequence represented by UniProtKB:O75173-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O75173-1, Thr-813, MOD:00005~GNO:G29068FM." [GlyGen:O75173-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hADAMTS4/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O75173-1, Thr-813, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O75173 ! a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O75173-2 name: a disintegrin and metalloproteinase with thrombospondin motifs 4 isoform h2 (human) def: "An a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75173-2." [PRO:DNx, UniProtKB:O75173] comment: Category=organism-sequence. synonym: "hADAMTS4/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "a disintegrin and metalloproteinase with thrombospondin motifs 4 isoform ADAMTS4_v1 (human)" EXACT [UniProtKB:O75173] xref: UniProtKB:O75173-2 is_a: PR:O75173 ! a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000003733 name: a disintegrin and metalloproteinase with thrombospondin motifs 4 def: "A protein that is a translation product of the human ADAMTS4 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "ADMP-1" EXACT [] synonym: "ADAMTS4" EXACT PRO-short-label [PRO:DNx] synonym: "ADAM-TS4" EXACT [] synonym: "ADAMTS-4" EXACT [] synonym: "KIAA0688" RELATED Gene-based [] synonym: "ADAM-TS 4" EXACT [] synonym: "aggrecanase-1" EXACT [] synonym: "UNQ769/PRO1563" RELATED Gene-based [] xref: IUPHARobj:1677 is_a: PR:000000001 ! protein [Term] id: PR:O75173-1 name: a disintegrin and metalloproteinase with thrombospondin motifs 4 isoform h1 (human) def: "An a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75173-1." [PRO:DNx, UniProtKB:O75173] comment: Category=organism-sequence. synonym: "hADAMTS4/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O75173-1 is_a: PR:O75173 ! a disintegrin and metalloproteinase with thrombospondin motifs 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens