[Term]
id: PR:P13196-1
name: 5-aminolevulinate synthase, non-specific, mitochondrial isoform h1 (human)
def: "A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13196-1." [PRO:DNx, UniProtKB:P13196]
comment: Category=organism-sequence.
synonym: "hALAS1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P13196-1
is_a: PR:P13196 ! 5-aminolevulinate synthase, non-specific, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000003916
name: 5-aminolevulinate synthase, non-specific, mitochondrial
def: "A 5-aminolevulinate synthase that is a translation product of the human ALAS1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "ALAS1" EXACT PRO-short-label [PRO:DNx]
synonym: "ALAS3" RELATED Gene-based []
synonym: "ALASH" RELATED Gene-based []
synonym: "ALAS-H" EXACT []
synonym: "OK/SW-cl.121" RELATED Gene-based []
synonym: "delta-ALA synthase 1" EXACT []
synonym: "5-aminolevulinic acid synthase 1" EXACT []
synonym: "delta-aminolevulinate synthase 1" EXACT []
is_a: PR:000026125 ! 5-aminolevulinate synthase

[Term]
id: PR:000046305
name: 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)
def: "A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P13196, 57-640, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022086]
comment: Category=organism-modification.
synonym: "PRO_0000001230, MOD:00128" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hALAS1/TransPep-/PyrdoxLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P13196, 57-640, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1022086 "PR:000046305 located_in GO:0005759"
intersection_of: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine
intersection_of: PR:P13196 ! 5-aminolevulinate synthase, non-specific, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046304
name: 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)
def: "A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P13196, 57-640." [PRO:DNx, Reactome:R-HSA-189438]
comment: Category=organism-modification.
synonym: "PRO_0000001230" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hALAS1/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P13196, 57-640" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-189438 "PR:000046304 located_in GO:0005759"
intersection_of: PR:P13196 ! 5-aminolevulinate synthase, non-specific, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13196-2
name: 5-aminolevulinate synthase, non-specific, mitochondrial isoform h2 (human)
def: "A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13196-2." [PRO:DNx, UniProtKB:P13196]
comment: Category=organism-sequence.
synonym: "hALAS1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P13196-2
is_a: PR:P13196 ! 5-aminolevulinate synthase, non-specific, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13196
name: 5-aminolevulinate synthase, non-specific, mitochondrial (human)
def: "A 5-aminolevulinate synthase, non-specific, mitochondrial that is encoded in the genome of human." [PRO:CNA, UniProtKB:P13196]
comment: Category=organism-gene.
synonym: "ALAS1" RELATED Gene-based [UniProtKB:P13196]
synonym: "ALAS3" RELATED Gene-based [UniProtKB:P13196]
synonym: "ALASH" RELATED Gene-based [UniProtKB:P13196]
synonym: "hALAS1" EXACT PRO-short-label [PRO:DNx]
synonym: "OK/SW-cl.121" RELATED Gene-based [UniProtKB:P13196]
synonym: "ALAS-H (human)" EXACT [UniProtKB:P13196]
synonym: "delta-ALA synthase 1 (human)" EXACT [UniProtKB:P13196]
synonym: "5-aminolevulinic acid synthase 1 (human)" EXACT [UniProtKB:P13196]
synonym: "delta-aminolevulinate synthase 1 (human)" EXACT [UniProtKB:P13196]
xref: UniProtKB:P13196
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003916 ! 5-aminolevulinate synthase, non-specific, mitochondrial
relationship: has_gene_template HGNC:396 ! ALAS1 (human)