[Term] id: PR:000003987 name: activating molecule in BECN1-regulated autophagy protein 1 def: "A protein that is a translation product of the human AMBRA1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "DCAF3" RELATED Gene-based [] synonym: "AMBRA1" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1736" RELATED Gene-based [] is_a: PR:000000001 ! protein [Term] id: PR:Q9C0C7-1 name: activating molecule in BECN1-regulated autophagy protein 1 isoform h1 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0C7-1." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-sequence. synonym: "hAMBRA1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0C7-1 is_a: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0C7-3 name: activating molecule in BECN1-regulated autophagy protein 1 isoform h3 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0C7-3." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-sequence. synonym: "hAMBRA1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0C7-3 is_a: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0C7-2 name: activating molecule in BECN1-regulated autophagy protein 1 isoform h2 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0C7-2." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-sequence. synonym: "hAMBRA1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0C7-2 is_a: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0C7-5 name: activating molecule in BECN1-regulated autophagy protein 1 isoform h5 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0C7-5." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-sequence. synonym: "hAMBRA1/iso:h5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0C7-5 is_a: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0C7-4 name: activating molecule in BECN1-regulated autophagy protein 1 isoform h4 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0C7-4." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-sequence. synonym: "hAMBRA1/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0C7-4 is_a: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0C7-6 name: activating molecule in BECN1-regulated autophagy protein 1 isoform h6 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0C7-6." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-sequence. synonym: "hAMBRA1/iso:h6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0C7-6 is_a: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0C7 name: activating molecule in BECN1-regulated autophagy protein 1 (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9C0C7] comment: Category=organism-gene. synonym: "DCAF3" RELATED Gene-based [UniProtKB:Q9C0C7] synonym: "AMBRA1" RELATED Gene-based [UniProtKB:Q9C0C7] synonym: "hAMBRA1" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1736" RELATED Gene-based [UniProtKB:Q9C0C7] synonym: "DDB1- and CUL4-associated factor 3 (human)" EXACT [UniProtKB:Q9C0C7] xref: Reactome:R-HSA-1632831 "PR:Q9C0C7 located_in GO:0005829" xref: UniProtKB:Q9C0C7 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003987 ! activating molecule in BECN1-regulated autophagy protein 1 relationship: has_gene_template HGNC:25990 ! AMBRA1 (human) [Term] id: PR:000046329 name: activating molecule in BECN1-regulated autophagy protein 1 phosphorylated form (human) def: "An activating molecule in BECN1-regulated autophagy protein 1 (human) that includes at least one phosphorylated residue. UniProtKB:Q9C0C7, MOD:00696." [PRO:DNx, Reactome:R-HSA-1632854] comment: Category=organism-modification. synonym: "hAMBRA1/PhosRes+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9C0C7, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1632854 "PR:000046329 located_in GO:0005829" intersection_of: has_part MOD:00696 ! phosphorylated residue intersection_of: PR:Q9C0C7 ! activating molecule in BECN1-regulated autophagy protein 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens