[Term]
id: PR:Q96BI3-2
name: gamma-secretase subunit APH-1A isoform 2 (human)
def: "A gamma-secretase subunit APH-1A isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAPH1A/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-secretase subunit APH-1A isoform S (human)" EXACT [UniProtKB:Q96BI3]
synonym: "gamma-secretase subunit APH-1A isoform Aph-alpha2 (human)" EXACT [UniProtKB:Q96BI3]
xref: UniProtKB:Q96BI3-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042445 ! gamma-secretase subunit APH-1A isoform 2

[Term]
id: PR:Q96BI3-3
name: gamma-secretase subunit APH-1A isoform h3 (human)
def: "A gamma-secretase subunit APH-1A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BI3-3." [PRO:DNx, UniProtKB:Q96BI3]
comment: Category=organism-sequence.
synonym: "hAPH1A/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96BI3-3
is_a: PR:Q96BI3 ! gamma-secretase subunit APH-1A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96BI3
name: gamma-secretase subunit APH-1A (human)
def: "A gamma-secretase subunit APH-1A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96BI3]
comment: Category=organism-gene.
synonym: "PSF" RELATED Gene-based [UniProtKB:Q96BI3]
synonym: "APH1A" RELATED Gene-based [UniProtKB:Q96BI3]
synonym: "CGI-78" RELATED Gene-based [UniProtKB:Q96BI3]
synonym: "hAPH1A" EXACT PRO-short-label [PRO:DNx]
synonym: "APH-1a (human)" EXACT [UniProtKB:Q96BI3]
synonym: "UNQ579/PRO1141" RELATED Gene-based [UniProtKB:Q96BI3]
synonym: "Aph-1alpha (human)" EXACT [UniProtKB:Q96BI3]
synonym: "presenilin-stabilization factor (human)" EXACT [UniProtKB:Q96BI3]
xref: Reactome:R-HSA-3211581 "PR:Q96BI3 located_in GO:0005886"
xref: Reactome:R-HSA-9010105 "PR:Q96BI3 located_in GO:0010008"
xref: UniProtKB:Q96BI3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004129 ! gamma-secretase subunit APH-1A
relationship: has_gene_template HGNC:29509 ! APH1A (human)

[Term]
id: PR:Q96BI3-1
name: gamma-secretase subunit APH-1A isoform 1 (human)
def: "A gamma-secretase subunit APH-1A isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAPH1A/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-secretase subunit APH-1A isoform L (human)" EXACT [UniProtKB:Q96BI3]
synonym: "gamma-secretase subunit APH-1A isoform Aph-alpha1 (human)" EXACT [UniProtKB:Q96BI3]
xref: UniProtKB:Q96BI3-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042444 ! gamma-secretase subunit APH-1A isoform 1

[Term]
id: PR:000004129
name: gamma-secretase subunit APH-1A
def: "A protein that is a translation product of the human APH1A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=Alzforum.
synonym: "PSF" RELATED Gene-based []
synonym: "APH1A" EXACT PRO-short-label [PRO:DNx]
synonym: "APH-1a" EXACT []
synonym: "CGI-78" RELATED Gene-based []
synonym: "Aph-1alpha" EXACT []
synonym: "UNQ579/PRO1141" RELATED Gene-based []
synonym: "presenilin-stabilization factor" EXACT []
is_a: PR:000000001 ! protein