[Term]
id: PR:P56818-1
name: beta-secretase 1 isoform 1 (mouse)
def: "A beta-secretase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mBACE1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P56818-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039837 ! beta-secretase 1 isoform 1

[Term]
id: PR:P56818
name: beta-secretase 1 (mouse)
def: "A beta-secretase 1 that is encoded in the genome of mouse." [OMA:P56818, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bace" RELATED Gene-based [UniProtKB:P56818]
synonym: "Bace1" RELATED Gene-based [UniProtKB:P56818]
synonym: "mBACE1" EXACT PRO-short-label [PRO:DNx]
synonym: "ASP2 (mouse)" EXACT [UniProtKB:P56818]
synonym: "Asp 2 (mouse)" EXACT [UniProtKB:P56818]
synonym: "memapsin-2 (mouse)" EXACT [UniProtKB:P56818]
synonym: "aspartyl protease 2 (mouse)" EXACT [UniProtKB:P56818]
synonym: "beta-site APP cleaving enzyme 1 (mouse)" EXACT [UniProtKB:P56818]
synonym: "membrane-associated aspartic protease 2 (mouse)" EXACT [UniProtKB:P56818]
synonym: "beta-site amyloid precursor protein cleaving enzyme 1 (mouse)" EXACT [UniProtKB:P56818]
xref: UniProtKB:P56818
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004615 ! beta-secretase 1
relationship: has_gene_template MGI:1346542 ! Bace1 (mouse)

[Term]
id: PR:000044620
name: beta-secretase 1 isoform 1 N-glycosylated 3 (mouse)
def: "A beta-secretase 1 isoform 1 (mouse) that has been glycosylated at the position equivalent to Asn-172 of the amino acid sequence represented by UniProtKB:P56818-1. UniProtKB:P56818-1, Asn-172, MOD:00160." [PMID:26467158, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26467158).
synonym: "mBACE1/iso:1/NGlyco:3" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P56818-1, Asn-172, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P56818-1 ! beta-secretase 1 isoform 1 (mouse)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044619
name: beta-secretase 1 isoform 1 N-glycosylated 1 (mouse)
def: "A beta-secretase 1 isoform 1 (mouse) that has been glycosylated at the position equivalent to Asn-153 of the amino acid sequence represented by UniProtKB:P56818-1. UniProtKB:P56818-1, Asn-153, MOD:00160." [PMID:26467158, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26467158).
synonym: "mBACE1/iso:1/NGlyco:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P56818-1, Asn-153, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P56818-1 ! beta-secretase 1 isoform 1 (mouse)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000004615
name: beta-secretase 1
def: "A protein that is a translation product of the human BACE1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=Alzforum.
synonym: "ASP2" EXACT []
synonym: "BACE" RELATED Gene-based []
synonym: "Asp 2" EXACT []
synonym: "BACE1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1149" RELATED Gene-based []
synonym: "memapsin-2" EXACT []
synonym: "aspartyl protease 2" EXACT []
synonym: "beta-site APP cleaving enzyme 1" EXACT []
synonym: "membrane-associated aspartic protease 2" EXACT []
synonym: "beta-site amyloid precursor protein cleaving enzyme 1" EXACT []
xref: IUPHARobj:2330
is_a: PR:000000001 ! protein

[Term]
id: PR:000044621
name: beta-secretase 1 isoform 1 N-glycosylated 2 (mouse)
def: "A beta-secretase 1 isoform 1 (mouse) that has been glycosylated at the position equivalent to Asn-223 of the amino acid sequence represented by UniProtKB:P56818-1. UniProtKB:P56818-1, Asn-223, MOD:00160." [PMID:26467158, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26467158).
synonym: "mBACE1/iso:1/NGlyco:2" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P56818-1, Asn-223, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P56818-1 ! beta-secretase 1 isoform 1 (mouse)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044622
name: beta-secretase 1 isoform 1 N-glycosylated 5 (mouse)
def: "A beta-secretase 1 isoform 1 (mouse) that has been glycosylated at positions equivalent to Asn-153 and Asn-223 of the amino acid sequence represented by UniProtKB:P56818-1. UniProtKB:P56818-1, Asn-153/Asn-223, MOD:00160." [PMID:26467158, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26467158).
synonym: "mBACE1/iso:1/NGlyco:5" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P56818-1, Asn-153/Asn-223, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P56818-1 ! beta-secretase 1 isoform 1 (mouse)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044623
name: beta-secretase 1 isoform 1 N-glycosylated 4 (mouse)
def: "A beta-secretase 1 isoform 1 (mouse) that has been glycosylated at the position equivalent to Asn-354 of the amino acid sequence represented by UniProtKB:P56818-1. UniProtKB:P56818-1, Asn-354, MOD:00160." [PMID:26467158, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26467158).
synonym: "mBACE1/iso:1/NGlyco:4" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P56818-1, Asn-354, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P56818-1 ! beta-secretase 1 isoform 1 (mouse)
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus