[Term] id: PR:000046463 name: brevican core protein, signal peptide removed form (human) def: "A brevican core protein (human) that has had the signal peptide removed. UniProtKB:Q96GW7, 23-911." [PRO:DNx, Reactome:R-HSA-2064073, Reactome:R-HSA-2065216] comment: Category=organism-modification. synonym: "hBCAN/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "PRO_0000017511" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "UniProtKB:Q96GW7, 23-911" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2064073 "PR:000046463 located_in GO:0005796" xref: Reactome:R-HSA-2065216 "PR:000046463 located_in GO:0043202" intersection_of: PR:Q96GW7 ! brevican core protein (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057875 name: brevican core protein O-glycosylated 1 (human) def: "A brevican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-384 of the amino acid sequence represented by UniProtKB:Q96GW7-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96GW7-1, Thr-384, MOD:00005~GNO:G43417UB." [GlyGen:Q96GW7-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hBCAN/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q96GW7-1, Thr-384, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q96GW7 ! brevican core protein (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000029978 name: brevican core protein phosphorylated 1 def: "A brevican core protein that has been phosphorylated on the residue at the position equivalent to Ser-546 of the amino acid sequence represented by UniProtKB:Q61361. Example: UniProtKB:Q61361, Ser-546, MOD:00046." [PMID:17114649, PRO:HJD] comment: Category=modification. Note: Large-scale experiment. synonym: "BCAN/Phos:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000004673 ! brevican core protein relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000057876 name: brevican core protein O-glycosylated 2 (human) def: "A brevican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-569 of the amino acid sequence represented by UniProtKB:Q96GW7-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96GW7-1, Thr-569, MOD:00005~GNO:G43417UB." [GlyGen:Q96GW7-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hBCAN/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q96GW7-1, Thr-569, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q96GW7 ! brevican core protein (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q96GW7 name: brevican core protein (human) def: "A brevican core protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96GW7] comment: Category=organism-gene. synonym: "BCAN" RELATED Gene-based [UniProtKB:Q96GW7] synonym: "BEHAB" RELATED Gene-based [UniProtKB:Q96GW7] synonym: "CSPG7" RELATED Gene-based [UniProtKB:Q96GW7] synonym: "hBCAN" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ2525/PRO6018" RELATED Gene-based [UniProtKB:Q96GW7] synonym: "chondroitin sulfate proteoglycan 7 (human)" EXACT [UniProtKB:Q96GW7] synonym: "brain-enriched hyaluronan-binding protein (human)" EXACT [UniProtKB:Q96GW7] xref: UniProtKB:Q96GW7 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000004673 ! brevican core protein relationship: has_gene_template HGNC:23059 ! BCAN (human) [Term] id: PR:000029979 name: brevican core protein phosphorylated 1 (mouse) def: "A brevican core protein phosphorylated 1 in mouse. UniProtKB:Q61361, Ser-546, MOD:00046." [PMID:17114649, PRO:HJD] comment: Category=organism-modification. Note: Large-scale experiment. synonym: "mBCAN/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q61361, Ser-546, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000029978 ! brevican core protein phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:P55068 name: brevican core protein (rat) def: "A brevican core protein that is encoded in the genome of rat." [PANTHER:PTHR22804:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "Bcan" RELATED Gene-based [UniProtKB:P55068] synonym: "Behab" RELATED Gene-based [UniProtKB:P55068] synonym: "rBCAN" EXACT PRO-short-label [PRO:DNx] synonym: "BEHAB (rat)" EXACT [UniProtKB:P55068] synonym: "brain-enriched hyaluronan-binding protein (rat)" EXACT [UniProtKB:P55068] xref: UniProtKB:P55068 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000004673 ! brevican core protein relationship: has_gene_template RGD:2194 ! Bcan (rat) [Term] id: PR:000004673 name: brevican core protein def: "A protein that is a translation product of the human BCAN gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "BCAN" EXACT PRO-short-label [PRO:DNx] synonym: "BEHAB" RELATED Gene-based [] synonym: "CSPG7" RELATED Gene-based [] synonym: "UNQ2525/PRO6018" RELATED Gene-based [] synonym: "chondroitin sulfate proteoglycan 7" EXACT [] synonym: "brain-enriched hyaluronan-binding protein" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q61361 name: brevican core protein (mouse) def: "A brevican core protein that is encoded in the genome of mouse." [OMA:Q61361, PRO:DNx] comment: Category=organism-gene. synonym: "Bcan" RELATED Gene-based [UniProtKB:Q61361] synonym: "mBCAN" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q61361 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000004673 ! brevican core protein relationship: has_gene_template MGI:1096385 ! Bcan (mouse) [Term] id: PR:Q96GW7-1 name: brevican core protein isoform h1 (human) def: "A brevican core protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GW7-1." [PRO:DNx, UniProtKB:Q96GW7] comment: Category=organism-sequence. synonym: "hBCAN/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q96GW7-1 is_a: PR:Q96GW7 ! brevican core protein (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P55068-1 name: brevican core protein isoform r1 (rat) def: "A brevican core protein (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55068-1." [PRO:DNx, UniProtKB:P55068] comment: Category=organism-sequence. synonym: "rBCAN/iso:r1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P55068-1 is_a: PR:P55068 ! brevican core protein (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P55068-2 name: brevican core protein isoform r2 (rat) def: "A brevican core protein (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55068-2." [PRO:DNx, UniProtKB:P55068] comment: Category=organism-sequence. synonym: "rBCAN/iso:r2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P55068-2 is_a: PR:P55068 ! brevican core protein (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q96GW7-2 name: brevican core protein isoform h2 (human) def: "A brevican core protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96GW7-2." [PRO:DNx, UniProtKB:Q96GW7] comment: Category=organism-sequence. synonym: "hBCAN/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q96GW7-2 is_a: PR:Q96GW7 ! brevican core protein (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens