[Term]
id: PR:000046507
name: serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 3 (human)
def: "A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at position 339 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-339, MOD:00046." [PRO:DNx, Reactome:R-HSA-1063700]
comment: Category=organism-modification.
synonym: "hBRAF/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000085665, Ser-339, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P15056, 2-766, Ser-339, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1063700 "PR:000046507 located_in GO:0005886"
is_a: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000046506
name: serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 2 (human)
def: "A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 151, 446, 602, 729, and 750, and phosphothreonine at positions 401, 599 and 753 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-151/Ser-446/Ser-602/Ser-729/Ser-750, MOD:00046|Thr-401/Thr-599/Thr-753, MOD:00047." [PRO:DAN, Reactome:R-HSA-5675199]
comment: Category=organism-modification. Note: A modified site indicated here (Ser-446) is referred to as Ser-445 in some manuscripts. [PRO:DAN, PMID:15710605]
synonym: "hBRAF/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000085665, Ser-151/Ser-446/Ser-602/Ser-729/Ser-750, MOD:00046|Thr-401/Thr-599/Thr-753, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P15056, 2-766, Ser-151/Ser-446/Ser-602/Ser-729/Ser-750, MOD:00046|Thr-401/Thr-599/Thr-753, MOD:00047" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5675199 "PR:000046506 located_in GO:0005886"
is_a: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000046505
name: serine/threonine-protein kinase B-raf, initiator methionine removed form (human)
def: "A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed. UniProtKB:P15056, 2-766." [PRO:DNx, Reactome:R-HSA-167224, Reactome:R-HSA-190063, Reactome:R-HSA-934547]
comment: Category=organism-modification.
synonym: "PRO_0000085665" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hBRAF/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15056, 2-766" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-167224 "PR:000046505 located_in GO:0005829"
xref: Reactome:R-HSA-190063 "PR:000046505 located_in GO:0005768"
xref: Reactome:R-HSA-934547 "PR:000046505 located_in GO:0005886"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046509
name: serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 5 (human)
def: "A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 446, 602 and 729, and phosphothreonine at position 599 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047." [PRO:DAN, Reactome:R-HSA-5672676, Reactome:R-HSA-5672679]
comment: Category=organism-modification. Note: A modified site indicated here (Ser-446) is referred to as Ser-445 in some manuscripts. [PRO:DAN, PMID:15710605]
synonym: "hBRAF/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000085665, Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5672676 "PR:000046509 located_in GO:0005829"
xref: Reactome:R-HSA-5672679 "PR:000046509 located_in GO:0005886"
is_a: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000046508
name: serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 4 (human)
def: "A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 365, 446 and 729 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-365/Ser-446/Ser-729, MOD:00046." [PRO:DAN, Reactome:R-HSA-5672667]
comment: Category=organism-modification. Note: A modified site indicated here (Ser-446) is referred to as Ser-445 in some manuscripts. [PRO:DAN, PMID:15710605]
synonym: "hBRAF/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000085665, Ser-365/Ser-446/Ser-729, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P15056, 2-766, Ser-365/Ser-446/Ser-729, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5672667 "PR:000046508 located_in GO:0005829"
is_a: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q07292
name: Raf homolog serine/threonine-protein kinase (worm)
def: "A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of worm." [OMA:Q07292, PRO:DNx]
comment: Category=organism-gene.
synonym: "raf-1" RELATED Gene-based [UniProtKB:Q07292]
synonym: "lin-45" RELATED Gene-based [UniProtKB:Q07292]
synonym: "Y73B6A.5" RELATED Gene-based [UniProtKB:Q07292]
synonym: "BRAF (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "abnormal cell lineage protein 45 (worm)" EXACT [UniProtKB:Q07292]
xref: UniProtKB:Q07292
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000004801 ! B-Raf proto-oncogene serine/threonine-protein kinase
relationship: has_gene_template WormBase:WBGene00003030 ! lin-45 (worm)

[Term]
id: PR:Q07292-1
name: Raf homolog serine/threonine-protein kinase isoform a (worm)
def: "A Raf homolog serine/threonine-protein kinase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07292-1." [PRO:DNx, UniProtKB:Q07292]
comment: Category=organism-sequence.
synonym: "BRAF/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07292-1
is_a: PR:Q07292 ! Raf homolog serine/threonine-protein kinase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q07292-3
name: Raf homolog serine/threonine-protein kinase isoform c (worm)
def: "A Raf homolog serine/threonine-protein kinase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07292-3." [PRO:DNx, UniProtKB:Q07292]
comment: Category=organism-sequence.
synonym: "BRAF/iso:c (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07292-3
is_a: PR:Q07292 ! Raf homolog serine/threonine-protein kinase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q04982-1
name: serine/threonine-protein kinase B-raf isoform Long (chicken)
def: "A serine/threonine-protein kinase B-raf (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04982-1." [PRO:DNx, UniProtKB:Q04982]
comment: Category=organism-sequence.
synonym: "chick-BRAF/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04982-1
is_a: PR:Q04982 ! serine/threonine-protein kinase B-raf (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q04982
name: serine/threonine-protein kinase B-raf (chicken)
def: "A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of chicken." [OMA:Q04982, PANTHER:PTHR23257:SF41, PRO:DNx]
comment: Category=organism-gene.
synonym: "BRAF" RELATED Gene-based [UniProtKB:Q04982]
synonym: "RMIL" RELATED Gene-based [UniProtKB:Q04982]
synonym: "chick-BRAF" EXACT PRO-short-label [PRO:DNx]
synonym: "proto-oncogene B-Raf (chicken)" EXACT [UniProtKB:Q04982]
synonym: "proto-oncogene c-Rmil (chicken)" EXACT [UniProtKB:Q04982]
synonym: "serine/threonine-protein kinase Rmil (chicken)" EXACT [UniProtKB:Q04982]
xref: UniProtKB:Q04982
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000004801 ! B-Raf proto-oncogene serine/threonine-protein kinase
relationship: has_gene_template NCBIGene:396239 ! BRAF (chicken)

[Term]
id: PR:P28028-1
name: serine/threonine-protein kinase B-raf isoform m1 (mouse)
def: "A serine/threonine-protein kinase B-raf (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28028-1." [PRO:DNx, UniProtKB:P28028]
comment: Category=organism-sequence.
synonym: "mBRAF/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28028-1
is_a: PR:P28028 ! serine/threonine-protein kinase B-raf (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P28028-3
name: serine/threonine-protein kinase B-raf isoform m3 (mouse)
def: "A serine/threonine-protein kinase B-raf (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28028-3." [PRO:DNx, UniProtKB:P28028]
comment: Category=organism-sequence.
synonym: "mBRAF/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28028-3
is_a: PR:P28028 ! serine/threonine-protein kinase B-raf (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049874
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 6 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-766. UniProtKB:P28028-1, Ser-766, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-766, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049875
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 7 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-787. UniProtKB:P28028-1, Ser-787, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-787, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049872
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 4 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-483 and Ser-484. UniProtKB:P28028-1, Ser-483/Ser-484, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-483/Ser-484, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049873
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 5 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-642. UniProtKB:P28028-1, Ser-642, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-642, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049870
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 2 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-316 and Ser-318. UniProtKB:P28028-1, Ser-316/Ser-318, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-316/Ser-318, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049871
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 3 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-348. UniProtKB:P28028-1, Ser-348, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-348, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P15056
name: serine/threonine-protein kinase B-raf (human)
def: "A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15056]
comment: Category=organism-gene.
synonym: "BRAF" RELATED Gene-based [UniProtKB:P15056]
synonym: "BRAF1" RELATED Gene-based [UniProtKB:P15056]
synonym: "RAFB1" RELATED Gene-based [UniProtKB:P15056]
synonym: "hBRAF" EXACT PRO-short-label [PRO:DNx]
synonym: "p94 (human)" BROAD [UniProtKB:P15056]
synonym: "proto-oncogene B-Raf (human)" EXACT [UniProtKB:P15056]
synonym: "v-Raf murine sarcoma viral oncogene homolog B1 (human)" EXACT [UniProtKB:P15056]
xref: DTO:03100047
xref: UniProtKB:P15056
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004801 ! B-Raf proto-oncogene serine/threonine-protein kinase
relationship: has_gene_template HGNC:1097 ! BRAF (human)

[Term]
id: PR:Q07292-2
name: Raf homolog serine/threonine-protein kinase isoform b (worm)
def: "A Raf homolog serine/threonine-protein kinase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07292-2." [PRO:DNx, UniProtKB:Q07292]
comment: Category=organism-sequence.
synonym: "BRAF/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07292-2
is_a: PR:Q07292 ! Raf homolog serine/threonine-protein kinase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:000046510
name: serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 6 (human)
def: "A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 446 and 729 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-446/Ser-729, MOD:00046." [PRO:DAN, Reactome:R-HSA-5672673]
comment: Category=organism-modification. Note: A modified site indicated here (Ser-446) is referred to as Ser-445 in some manuscripts. [PRO:DAN, PMID:15710605]
synonym: "hBRAF/InitMet-/Phos:6" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000085665, Ser-446/Ser-729, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DAN]
synonym: "UniProtKB:P15056, 2-766, Ser-446/Ser-729, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5672673 "PR:000046510 located_in GO:0005829"
xref: Reactome:R-HSA-8933622 "PR:000046510 located_in GO:0005886"
is_a: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P28028
name: serine/threonine-protein kinase B-raf (mouse)
def: "A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of mouse." [OMA:MOUSE18293, PRO:DNx]
comment: Category=organism-gene.
synonym: "Braf" RELATED Gene-based [UniProtKB:P28028]
synonym: "B-raf" RELATED Gene-based [UniProtKB:P28028]
synonym: "mBRAF" EXACT PRO-short-label [PRO:DNx]
synonym: "proto-oncogene B-Raf (mouse)" EXACT [UniProtKB:P28028]
xref: UniProtKB:P28028
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004801 ! B-Raf proto-oncogene serine/threonine-protein kinase
relationship: has_gene_template MGI:88190 ! Braf (mouse)

[Term]
id: PR:000045681
name: serine/threonine-protein kinase B-raf phosphorylated 1 (human)
def: "A serine/threonine-protein kinase B-raf (human) that has been phosphorylated at Thr-753. UniProtKB:P15056, Thr-753, MOD:00047." [PMID:16508002, iPTMnet:P15056]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:16508002). Status=unreviewed.
synonym: "hBRAF/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15056, Thr-753, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P15056 ! serine/threonine-protein kinase B-raf (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000004801
name: B-Raf proto-oncogene serine/threonine-protein kinase
def: "A protein that is a translation product of the human BRAF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "p94" BROAD [PRO:DNx]
synonym: "BRAF" EXACT PRO-short-label [PRO:DNx]
synonym: "B-raf" RELATED Gene-based []
synonym: "BRAF1" RELATED Gene-based []
synonym: "RAFB1" RELATED Gene-based []
synonym: "proto-oncogene B-Raf" EXACT []
synonym: "v-Raf murine sarcoma viral oncogene homolog B1" EXACT []
xref: IUPHARobj:1943
is_a: PR:000000001 ! protein

[Term]
id: PR:Q04982-2
name: serine/threonine-protein kinase B-raf isoform Short (chicken)
def: "A serine/threonine-protein kinase B-raf (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04982-2." [PRO:DNx, UniProtKB:Q04982]
comment: Category=organism-sequence.
synonym: "chick-BRAF/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04982-2
is_a: PR:Q04982 ! serine/threonine-protein kinase B-raf (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:000049869
name: serine/threonine-protein kinase B-raf isoform m1 phosphorylated 1 (mouse)
def: "A serine/threonine-protein kinase B-raf isoform m1 (mouse) that has been phosphorylated at Ser-135. UniProtKB:P28028-1, Ser-135, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mBRAF/iso:m1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28028-1, Ser-135, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P28028-1 ! serine/threonine-protein kinase B-raf isoform m1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000019146
name: B-Raf proto-oncogene serine/threonine-protein kinase, initiator methionine removed form
def: "A B-Raf proto-oncogene serine/threonine-protein kinase that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "BRAF/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000004801 ! B-Raf proto-oncogene serine/threonine-protein kinase
intersection_of: lacks_part PR:000021937 ! initiator methionine