[Term]
id: PR:Q54DM1
name: mitotic checkpoint protein bub3 (Dictyostelium discoideum)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54DM1, PANTHER:PTHR10971:SF5, PRO:DNx]
comment: Category=organism-gene.
synonym: "bub3" RELATED Gene-based [UniProtKB:Q54DM1]
synonym: "Dicty-BUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0292134" RELATED Gene-based [UniProtKB:Q54DM1]
xref: UniProtKB:Q54DM1
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template dictyBase:DDB_G0292134 ! bub3 (Dictyostelium discoideum)

[Term]
id: PR:000035454
name: mitotic checkpoint protein BUB3 unphosphorylated form (human)
def: "A mitotic checkpoint protein BUB3 unphosphorylated form in human." [PRO:KER]
comment: Category=organism-modification. Kinase=("BUB1"; PR:O43683).
synonym: "hBUB3/PhosRes-" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035453 ! mitotic checkpoint protein BUB3 unphosphorylated form

[Term]
id: PR:000035453
name: mitotic checkpoint protein BUB3 unphosphorylated form
def: "A mitotic checkpoint protein BUB3 that lacks phosphorylated residues." [PRO:KER]
comment: Category=modification.
synonym: "BUB3/PhosRes-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3

[Term]
id: PR:000038165
name: mitotic checkpoint protein BUB3 isoform 2
def: "A mitotic checkpoint protein BUB3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43684-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "BUB3/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004856 ! mitotic checkpoint protein BUB3

[Term]
id: PR:O43684
name: mitotic checkpoint protein BUB3 (human)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43684]
comment: Category=organism-gene.
synonym: "BUB3" RELATED Gene-based [UniProtKB:O43684]
synonym: "hBUB3" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-141416 "PR:O43684 located_in GO:0005829"
xref: UniProtKB:O43684
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template HGNC:1151 ! BUB3 (human)

[Term]
id: PR:O42860
name: mitotic checkpoint protein bub3 (Schizosaccharomyces pombe 972h-)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O42860, PRO:KER]
comment: Category=organism-gene.
synonym: "bub3" RELATED Gene-based [UniProtKB:O42860]
synonym: "SPAC23H3.08c" RELATED Gene-based [UniProtKB:O42860]
synonym: "Spom972h-BUB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O42860
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template PomBase:SPAC23H3.08c ! bub3 (Schizosaccharomyces pombe)

[Term]
id: PR:000045593
name: mitotic checkpoint protein BUB3 phosphorylated 2 (human)
def: "A mitotic checkpoint protein BUB3 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-207 of the amino acid sequence represented by UniProtKB:O43684-1. Example: UniProtKB:O43684-1, Tyr-207, MOD:00048." [PMID:24316223, iPTMnet:O43684]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:24316223). Status=unreviewed.
synonym: "hBUB3/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43684-1, Tyr-207, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O43684 ! mitotic checkpoint protein BUB3 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9YGY3
name: mitotic checkpoint protein BUB3 (frog)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of frog." [PRO:KER]
comment: Category=organism-gene.
synonym: "bub3" RELATED Gene-based [UniProtKB:Q9YGY3]
synonym: "xbub3" EXACT [UniProtKB:Q9YGY3]
synonym: "frog-BUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "WD repeat protein Bub3 (frog)" EXACT [UniProtKB:Q9YGY3]
xref: UniProtKB:Q9YGY3
intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template NCBIGene:399106 ! bub3 (frog)

[Term]
id: PR:O43684-2
name: mitotic checkpoint protein BUB3 isoform 2 (human)
def: "A mitotic checkpoint protein BUB3 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hBUB3/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43684-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038165 ! mitotic checkpoint protein BUB3 isoform 2

[Term]
id: PR:O43684-1
name: mitotic checkpoint protein BUB3 isoform h1 (human)
def: "A mitotic checkpoint protein BUB3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43684-1." [PRO:DNx, UniProtKB:O43684]
comment: Category=organism-sequence.
synonym: "hBUB3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43684-1
is_a: PR:O43684 ! mitotic checkpoint protein BUB3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9XWH0
name: mitotic checkpoint protein bub-3 (worm)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of worm." [OMA:Q9XWH0, PANTHER:PTHR10971:SF5, PRO:DNx]
comment: Category=organism-gene.
synonym: "bub-3" RELATED Gene-based [UniProtKB:Q9XWH0]
synonym: "Y54G9A.6" RELATED Gene-based [UniProtKB:Q9XWH0]
synonym: "BUB3 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "budding uninhibited by benzimidazole 3 (worm)" EXACT [UniProtKB:Q9XWH0]
xref: UniProtKB:Q9XWH0
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template WormBase:WBGene00013209 ! bub-3 (worm)

[Term]
id: PR:Q9WVA3-1
name: mitotic checkpoint protein BUB3 isoform 1 (mouse)
def: "A mitotic checkpoint protein BUB3 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mBUB3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9WVA3-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038165 ! mitotic checkpoint protein BUB3 isoform 2

[Term]
id: PR:Q9WVA3
name: mitotic checkpoint protein BUB3 (mouse)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of mouse." [OMA:Q9WVA3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bub3" RELATED Gene-based [UniProtKB:Q9WVA3]
synonym: "mBUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "WD repeat type I transmembrane protein A72.5 (mouse)" EXACT [UniProtKB:Q9WVA3]
xref: UniProtKB:Q9WVA3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template MGI:1343463 ! Bub3 (mouse)

[Term]
id: PR:000004856
name: mitotic checkpoint protein BUB3
def: "A protein that is a translation product of the human BUB3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "WD repeat type I transmembrane protein A72.5" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000035437
name: mitotic checkpoint protein BUB3 phosphorylated 1 (human)
def: "A mitotic checkpoint protein BUB3 phosphorylated 1 in human. Phosphorylated on the Ser residue within the motif D[YG]ISx[IV]K. UniProtKB:O43684, Ser-18, MOD:00046." [PMID:20057499, PRO:DAN, PRO:KER]
comment: Category=organism-modification. Kinase=("BUB1"; PR:O43683).
synonym: "hBUB3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43684, Ser-18, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035436 ! mitotic checkpoint protein BUB3 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000035436
name: mitotic checkpoint protein BUB3 phosphorylated 1
def: "A mitotic checkpoint protein BUB3 that has been phosphorylated by BUB1. Example: UniProtKB:O43684, Ser-18, MOD:00046." [PMID:20057499, PMID:7969164, PRO:DAN, PRO:KER]
comment: Category=modification.
synonym: "BUB3/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:Q9YGY3-2
name: mitotic checkpoint protein BUB3 isoform 2 (frog)
def: "A mitotic checkpoint protein BUB3 (frog) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9YGY3-2." [PRO:DNx, UniProtKB:Q9YGY3]
comment: Category=organism-sequence.
synonym: "frog-BUB3/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9YGY3-2
is_a: PR:Q9YGY3 ! mitotic checkpoint protein BUB3 (frog)
relationship: only_in_taxon NCBITaxon:8355 ! Xenopus laevis

[Term]
id: PR:000035438
name: cell cycle arrest protein BUB3 phosphorylated 1 (yeast)
def: "A mitotic checkpoint protein BUB3 phosphorylated 1 in yeast. UniProtKB:P26449, Ser-15, MOD:00046." [PMID:7969164, PRO:DAN, PRO:KER]
comment: Category=organism-modification. Kinase=("BUB1"; PR:000035401).
synonym: "yBUB3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P26449, Ser-15, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000035436 ! mitotic checkpoint protein BUB3 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:Q9YGY3-1
name: mitotic checkpoint protein BUB3 isoform 1 (frog)
def: "A mitotic checkpoint protein BUB3 (frog) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9YGY3-1." [PRO:DNx, UniProtKB:Q9YGY3]
comment: Category=organism-sequence.
synonym: "frog-BUB3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9YGY3-1
is_a: PR:Q9YGY3 ! mitotic checkpoint protein BUB3 (frog)
relationship: only_in_taxon NCBITaxon:8355 ! Xenopus laevis

[Term]
id: PR:P26449
name: cell cycle arrest protein BUB3 (yeast)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of yeast." [OMA:P26449, PRO:KER]
comment: Category=organism-gene.
synonym: "BUB3" RELATED Gene-based [UniProtKB:P26449]
synonym: "yBUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "OR26.16" RELATED Gene-based [UniProtKB:P26449]
synonym: "YOR026W" RELATED Gene-based [UniProtKB:P26449]
xref: UniProtKB:P26449
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000004856 ! mitotic checkpoint protein BUB3
relationship: has_gene_template SGD:S000005552 ! BUB3 (yeast)