[Term]
id: PR:P06681
name: complement C2 (human)
def: "A complement C2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P06681]
comment: Category=organism-gene.
synonym: "C2" RELATED Gene-based [UniProtKB:P06681]
synonym: "hC2" EXACT PRO-short-label [PRO:DNx]
synonym: "C3/C5 convertase (human)" BROAD [UniProtKB:P06681]
xref: UniProtKB:P06681
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004899 ! complement C2
relationship: has_gene_template HGNC:1248 ! C2 (human)

[Term]
id: PR:000004899
name: complement C2
def: "A protein that is a translation product of the human C2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "C2" EXACT PRO-short-label [PRO:DNx]
synonym: "C3/C5 convertase" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000046529
name: complement C2, signal peptide removed form (human)
def: "A complement C2 (human) that has had the signal peptide removed. UniProtKB:P06681, 21-752." [PRO:DNx, Reactome:R-HSA-166778]
comment: Category=organism-modification.
synonym: "hC2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000027610" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P06681, 21-752" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-166778 "PR:000046529 located_in GO:0005576"
intersection_of: PR:P06681 ! complement C2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06681-1
name: complement C2 isoform h1 (human)
def: "A complement C2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06681-1." [PRO:DNx, UniProtKB:P06681]
comment: Category=organism-sequence.
synonym: "hC2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06681-1
is_a: PR:P06681 ! complement C2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06681-3
name: complement C2 isoform h3 (human)
def: "A complement C2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06681-3." [PRO:DNx, UniProtKB:P06681]
comment: Category=organism-sequence.
synonym: "hC2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06681-3
is_a: PR:P06681 ! complement C2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06681-2
name: complement C2 isoform h2 (human)
def: "A complement C2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06681-2." [PRO:DNx, UniProtKB:P06681]
comment: Category=organism-sequence.
synonym: "hC2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06681-2
is_a: PR:P06681 ! complement C2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053590
name: complement C2 N-glycosylated 1 (human)
def: "A complement C2 (human) that has been N-glycosylated at the residue equivalent to Asn-651 of the amino acid sequence represented by UniProtKB:P06681-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P06681-1, Asn-651, MOD:00160~GNO:G00912UN." [GlyGen:P06681-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hC2/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06681-1, Asn-651, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06681 ! complement C2 (human)
relationship: has_part GNO:G00912UN ! G00912UN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053591
name: complement C2 N-glycosylated 2 (human)
def: "A complement C2 (human) that has been N-glycosylated at the residue equivalent to Asn-651 of the amino acid sequence represented by UniProtKB:P06681-1, in which the glycan composition is represented by GlyTouCan:G12580WI. Example: UniProtKB:P06681-1, Asn-651, MOD:00160~GNO:G12580WI." [GlyGen:P06681-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hC2/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06681-1, Asn-651, MOD:00160~GNO:G12580WI" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06681 ! complement C2 (human)
relationship: has_part GNO:G12580WI ! G12580WI
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens