[Term]
id: PR:P30307-5
name: M-phase inducer phosphatase 3 isoform h3 (human)
def: "An M-phase inducer phosphatase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30307-5." [PRO:DNx, UniProtKB:P30307]
comment: Category=organism-sequence.
synonym: "hCDC25C/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "M-phase inducer phosphatase 3 isoform CDC25C3 (human)" EXACT [UniProtKB:P30307]
xref: UniProtKB:P30307-5
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046661
name: M-phase inducer phosphatase 3 phosphorylated 3 (human)
def: "An M-phase inducer phosphatase 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-191 of the amino acid sequence represented by UniProtKB:P30307. UniProtKB:P30307, Ser-191, MOD:00046." [PRO:DNx, Reactome:R-HSA-6802968]
comment: Category=organism-modification.
synonym: "hCDC25C/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P30307, Ser-191, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6802968 "PR:000046661 located_in GO:0005654"
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P30307-3
name: M-phase inducer phosphatase 3 isoform h4 (human)
def: "An M-phase inducer phosphatase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30307-3." [PRO:DNx, UniProtKB:P30307]
comment: Category=organism-sequence.
synonym: "hCDC25C/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "M-phase inducer phosphatase 3 isoform CDC25C4 (human)" EXACT [UniProtKB:P30307]
xref: UniProtKB:P30307-3
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P30307-2
name: M-phase inducer phosphatase 3 isoform h2 (human)
def: "An M-phase inducer phosphatase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30307-2." [PRO:DNx, UniProtKB:P30307]
comment: Category=organism-sequence.
synonym: "hCDC25C/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "M-phase inducer phosphatase 3 isoform CDC25C2 (human)" EXACT [UniProtKB:P30307]
xref: UniProtKB:P30307-2
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P30307-1
name: M-phase inducer phosphatase 3 isoform h1 (human)
def: "An M-phase inducer phosphatase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30307-1." [PRO:DNx, UniProtKB:P30307]
comment: Category=organism-sequence.
synonym: "hCDC25C/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "M-phase inducer phosphatase 3 isoform CDC25C1 (human)" EXACT [UniProtKB:P30307]
xref: UniProtKB:P30307-1
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045745
name: M-phase inducer phosphatase 3 phosphorylated 2 (human)
def: "An M-phase inducer phosphatase 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-216 of the amino acid sequence represented by UniProtKB:P30307-1. Example: UniProtKB:P30307-1, Ser-216, MOD:00046." [PMID:10681541, PMID:10744722, PMID:10786669, PMID:14681223, PMID:15150265, PMID:16481012, PMID:9278511, PMID:9278512, PMID:9543386, PMID:9836640, iPTMnet:P30307]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10681541, PMID:10744722, PMID:10786669, PMID:14681223, PMID:15150265, PMID:16481012, PMID:9278511, PMID:9278512, PMID:9543386, PMID:9836640). Status=unreviewed.
synonym: "hCDC25C/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P30307-1, Ser-216, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-75003 "PR:000045745 located_in GO:0005829"
xref: Reactome:R-HSA-156496 "PR:000045745 located_in GO:0005654"
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P30307-4
name: M-phase inducer phosphatase 3 isoform h5 (human)
def: "An M-phase inducer phosphatase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30307-4." [PRO:DNx, UniProtKB:P30307]
comment: Category=organism-sequence.
synonym: "hCDC25C/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "M-phase inducer phosphatase 3 isoform CDC25C5 (human)" EXACT [UniProtKB:P30307]
synonym: "M-phase inducer phosphatase 3 isoform Cdc25Cdm (human)" EXACT [UniProtKB:P30307]
xref: UniProtKB:P30307-4
is_a: PR:P30307 ! M-phase inducer phosphatase 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P30307
name: M-phase inducer phosphatase 3 (human)
def: "An M-phase inducer phosphatase 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P30307]
comment: Category=organism-gene.
synonym: "CDC25C" RELATED Gene-based [UniProtKB:P30307]
synonym: "hCDC25C" EXACT PRO-short-label [PRO:DNx]
synonym: "dual specificity phosphatase Cdc25C (human)" EXACT [UniProtKB:P30307]
xref: Reactome:R-HSA-69741 "PR:P30307 located_in GO:0005654"
xref: Reactome:R-HSA-157879 "PR:P30307 located_in GO:0005829"
xref: UniProtKB:P30307
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005193 ! M-phase inducer phosphatase 3
relationship: has_gene_template HGNC:1727 ! CDC25C (human)

[Term]
id: PR:000035546
name: M-phase inducer phosphatase 3 phosphorylated 1 (human)
def: "An M-phase inducer phosphatase 3 phosphorylated 1 in human. UniProtKB:P30307, Ser-198, MOD:00046." [PMID:19503101, PRO:KER]
comment: Category=organism-modification. Kinase=("PLK1"; PR:P53350).
synonym: "hCDC25C/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P30307, Ser-198, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-156668 "PR:000035546 located_in GO:0005654"
xref: Reactome:R-HSA-8981697 "PR:000035546 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035545 ! M-phase inducer phosphatase 3 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000005193
name: M-phase inducer phosphatase 3
def: "A protein that is a translation product of the human CDC25C gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CDC25C" EXACT PRO-short-label [PRO:DNx]
synonym: "Cdc25m1" RELATED Gene-based []
synonym: "dual specificity phosphatase Cdc25C" EXACT []
is_a: PR:000000001 ! protein